2 B12 TAB

Uses and Benefits

2 B12 tablet is a nutritional and dietary supplement prescribed for the treatment of vitamin B deficiency, anaemias of nutritional supplements, pregnancy, infancy or childhood, megaloblastic anaemia and peripheral neuropathies. The capsule improves nerve conduction and speed, which reduces nerve pain and improves neuropathy and regulates blood calcium levels in the body. The tablet helps in reducing tiredness, fatigue, protects cells from oxidative stress and keeps your skin, hair and nails healthy. It makes up the deficiencies in the body and protection of cells from wear and tear. However, the uses of the tablet mentioned here are not exhaustive, there may be other reasons or situations in which the medicine might be used.

Composition

2 B12 tablet is a combination of Adenosyl cobalamin (750Mg), Folic acid (1.5Mg), Mecobalamin (750Mcg), Vitamin B1 (5Mg), Vitamin B2 (5Mg) and Vitamin B6 (3Mg)

Mechanism of Action of Drugs

2 B12 tablet contains B-complex vitamins that work together to help build a stronger immune system and maintain overall health. Thiamine (Vitamin B1) helps to produce certain neurotransmitters and carry out multiple enzyme processes. Riboflavin (Vitamin B2) plays an important role in the breakdown of carbohydrates, proteins, and fats to produce energy and is necessary for coenzymes activation, tissue respiration, and synthesis of macromolecules. Pyridoxine (Vitamin B6) aids in improving metabolism, strengthening immunity, and supporting the function of the nervous system. Mecobalamin strengthens our nervous system and plays a key part in DNA synthesis and maturation. Folic acid helps in lowering elevated homocysteine levels and also plays a key role in helping the body make red blood cells, thus helps in treating anaemias.

Contraindications and Caution

Patients with following conditions are suggested to seek advice from their healthcare professionals before taking 2 B12 tablet:

• Hypersensitivity to any of the active ingredients or excipients used in the tablet
• Damaged gastrointestinal tract
• Systemic mastocytosis
• Undiagnosed megaloblastic anaemia

• Caution:
• Phenylketonuria
• Alcohol dependence
• Pernicious anaemia
• Immunocompromised patients
• Hepatic impairment
• Renal impairment
• Diabetes mellitus
• Pregnancy and lactation

Side and Adverse Effects

The following side effects may or may not occur during the usage of 2 B12 tablet. When taken in the recommended dosage guidelines, it is usually well tolerated. You may experience one or more of the following side effects:

• Nausea
• Abdominal cramps
• Diarrhea
• Stomach upset
• Loss of appetite
• Vomiting
• Flatulence
• Headache
• Flushing
• Metallic taste

Rare but more serious adverse effects may include:

• Bronchospasm
• Weight loss
• Anorexia
• Diaphoresis
• Acute renal failure

How to Use

Take 2 B12 tablet as instructed by your doctor. Swallow the tablet whole with water, immediately after opening it from the strip. Do not break or crush or chew the tablet.
Avoid missing or forgetting the dose. If you do, take it as soon as you remember; but if it’s almost time for your next dose, skip it and take it according to your normal schedule. Don’t swallow two doses at the same time which is dangerous to your health.
Take the tablet once daily preferably after food. Take the tablet at the same time every day as it helps to maintain a consistent level of medicine in the body.
Do not change the dose or stop taking the medicine before completion of the course or without consulting your doctor. Continue to use this drug until completion of the maximum amount suggested.

Warnings and Precautions

Take 2 B12 tablet on the advice of medical practitioner. Dosage adjustments or complete avoidance of the medication may be required in the following conditions:

Kidney:

Since there is not enough reliable information about the safety of taking this tablet for renal patients, consult your doctor if you have kidney problems and stay on the safe side.

Liver:

Since there is not enough reliable information about the safety of taking this tablet for hepatic patients, consult your doctor if you have hepatic problems and stay on the safe side.

Pregnancy:

Use of this medicine in pregnancy is not considered safe in pregnant women unless the potential benefits outweigh the risks involved. Since limited information is available about the safety of taking 2 B12 tablet, consult your doctor if you are pregnant.

Lactation:

This medication is passed to infants through mother’s milk. Breastfed infants should be closely monitored. Since limited information is available about the safety of taking this tablet, consult your doctor if you are nursing mother and stay on the safe side.

Alcohol:

Consumption of alcohol with this medicine is not recommended as it increases side effects such as of the medicine. Any symptoms of abnormal reactions after taking the tablet should be reported to your doctor immediately. If you consume alcohol on regular basis, relevant dose adjustments may be necessary depending on your clinical condition.

Driving:

This medicine does not cause drowsiness or dizziness. If you notice any abnormal reactions after taking the tablet, do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

Food:

There are no known food interactions with this tablet.

Drug Interactions:

All medicines interact differently for person to person. Inform your doctor or pharmacist if you are taking any other medicines which includes over-the-counter drugs, herbal tonics, supplements and medicines that you buy without a prescription. Alert your doctor if you are taking 2 B12 tablet with aspirin, barbiturates, cimetidine, ciprofloxacin, antibiotics (chloramphenicol), anti-seizure drugs (phenytoin), cisplatin, altretamine, methotrexate.

FDA Pregnancy Category

Category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.