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    • 1 Units/pack

      MRP 11.68

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      4D tablet
      Uses and Benefits

      Uses and Benefits

      4D tablet is a combination anti-tubercular medicine that helps to treat tuberculosis which is a lung disease caused by Mycobacterium tuberculosis. It stops the growth of infection causing bacteria and reduces the spread of infection. However, the uses of this tablet mentioned here are not comprehensive, there may be other conditions for which the medication may be used upon your doctor’s discretion.

      Composition

      Composition

      The active ingredients of 4D tablet are Ethambutol 800 MG, Isoniazid (INH) 300 MG, Pyrazinamide 750 MG and Rifampicin 450 MG

      Mechanism of Action of Drugs

      Mechanism of Action of Drugs

      Ethambutol and isoniazid are antibiotics that works by preventing synthesis of essential proteins required by bacteria that causes tuberculosis, to carry out vital functions, thereby stopping bacterial growth and prevents spreading of infection. Rifampicin works by interfering with the bacterial DNA synthesis and inactivates bacterial enzymes (RNA-polymerase) and stops the growth of bacteria. Pyrazinamide works by altering the pH in the bacterial cells and stops its growth.

      Contraindications and Cautions

      Contraindications and Caution

      Patients with following conditions are suggested to seek advice from their healthcare professionals before using 4Dtablet:

      • Hypersensitivity to any of the components used in the tablet
      • Optic and retrobulbar neuritis
      • Severe hepatic impairment
      • Concomitant use with antiviral medications
      • Acute gout
      • Caution:
      • Ocular disease (diabetic retinopathy, cataracts)
      • Diabetes mellitus
      • Peripheral neuropathy
      • Renal and hepatic impairment
      • Children
      • Pregnancy and lactation
      Side Effects

      Side and Adverse Effects

      4D tablet is usually well tolerated when used in the prescribed dosage guidelines. Most side effects are temporary and usually subsides on their own. However, consult your doctor if they persist for a longer duration. You may experience one or more of the following symptoms:

      • Color blindness
      • Visual impairment
      • Pain and swelling of joints
      • Chills
      • Headache
      • Loss of appetite
      • Nausea or vomiting
      • Rash
      • Sweating
      • Salivation
      • Increased liver enzymes
      • Fever
      • Dark colored urine
      • Sweating
      • Watery eyes
      • Increased uric acid level in blood
      How to Use

      How to Use

      Take 4D tablet as instructed by your doctor. Swallow the tablet whole with water, immediately after opening it from the strip. Do not break or crush or chew the tablet.
      Avoid missing or forgetting the dose. If you do, take it as soon as you remember; but if it’s almost time for your next dose, skip it and take it according to your normal schedule. Don’t swallow two doses at the same time which is dangerous to your health.
      The tablet should be taken on an empty stomach at least 1-2 hours before or after a meal since food decreases the absorption of the medicine. Take the tablet at the same time every day as it helps to maintain a consistent level of medicine in the body.
      Do not change the dose or stop taking the medicine before completion of the course or without consulting your doctor. Continue to use this drug until completion of the maximum amount suggested even though the symptoms disappear after the medicine has begun. Stopping the medication too early can allow the growth of the bacteria to begin, which can lead to an infection relapse.

      Overdosage

      Avoid taking 4D tablet more than the prescribed dosage. In case of overdose, promptly seek medical advice. Depending on the dosage of the medicine, symptoms may vary in individuals, you may experience the following signs or symptoms:

      • Loss of vision or blurred vision
      • Skin rash
      • Peripheral neuropathy (Burning or tingling sensation of hands and feet)
      • Jaundice
      • Unusual bleeding or bruising
      • Hepatotoxicity
      Warnings and Precautions

      Warnings and Precautions

      Use 4D tablet on the advice of medical practitioner. Complete avoidance of the medication may be required in the following conditions:

      Kidney:

      Caution is advised among patients with severe renal impairment. Dose adjustments of the tablet may be needed. Regular monitoring of kidney function tests is recommended while taking this tablet. If you have any renal problems, it is highly recommended that you consult your doctor before taking this medicine.

      Liver:

      Extreme caution is advised among patients with moderate to severe liver disease. We highly recommend that you consult your doctor before the use. Inform your doctor if you develop signs of jaundice like yellowing of skin and eyes, itching and clay-colored stools while taking this tablet.

      Pregnancy:

      This medicine is not considered safe to use in pregnant women unless the potential benefits outweigh the risks involved. Despite the fact that there are limited studies in humans, animal studies have shown no or low adverse effects on the developing baby. It is recommended that you consult your doctor before consuming this tablet.

      Lactation:

      This medication is passed to infants through mother’s milk. Breastfed infants should be closely monitored. Since limited information is available about the safety of taking this tablet, consult your doctor if you are nursing mother and stay on the safe side.

      Alcohol:

      Consumption of alcohol with this tablet is not recommended as it may significantly increase the side effects of the medicine like severe abdominal pain, yellowing of the skin or eyes, flushing, increased heartbeat, chest pain and low blood pressure (disulfiram reaction). If you notice any unusual or abnormal reactions after taking the medicine, report to your doctor immediately.

      Driving:

      This medicine may decrease alertness, cause impaired judgement, affect your vision and make you feel dizzy, difficulty in concentration, fatigue. Do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

      Food:

      Tyramine rich food such as smoked fish, meats cheese should be avoided.

      Drug Interactions:

      All medicines interact differently for person to person. Inform your doctor or pharmacist if you are taking any other medicines which includes over-the-counter drugs, herbal tonics, supplements and medicines that you buy without a prescription. Alert your doctor if you’re taking 4D tablet along with propranolol, pimozide, methotrexate, halothane, citalopram, warfarin, clopidogrel, leflunomide, teriflunomide, antacids, cholera vaccine, atorvastatin, aluminium hydroxide.

      Precautions
      • Do not use this tablet post the expiry date
      • Do not use the tablet for durations shorter or longer than suggested by your doctor
      • Store at room temperature (20-30 degree Celsius)
      FDA Pregnancy Category

      FDA Pregnancy Category

      Category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


      Drug Composition information
      What is Ethambutol for:

      It is used to treat TB (tuberculosis).

      How does Ethambutol work:

      Ethambutol works to harm the bacteria and fight the infection.

      How should Ethambutol be used:

      To gain the most benefit, do not miss doses. Use as you have been told, even if you are feeling better. Take with or without food. Take with food if it causes an upset stomach.

      Common side effects of Ethambutol :

      Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. - Change in eyesight may rarely happen. Eyesight most often gets back to normal when this drug is stopped.

      What do I do if I miss a dose

      Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.

      What precautions should I take when taking Ethambutol :

      If you have an allergy to ethambutol or any other part of this drug. Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you have swelling in the eye.

      When do I need to seek medical help

      If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. If you have red-green color blindness. Change in thinking clearly and with logic. Very upset stomach or throwing up. Sudden change in eyesight, eye pain, or irritation. Any rash. Side effect or health problem is not better or you are feeling worse.

      Can I take Ethambutol with other medicines:

      Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.

      Are there any food restrictions

      Avoid Alcohol

      How do I store Ethambutol :

      Store in a cool, dry place away from the reach of children. - Medicines must not be used past the expiry date.

      Pregnancy Category

      Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.

      Therapeutic Classification

      Anti-TB Agents


      Frequently Asked Questions

      Frequently Asked Questions
      Q1. What is the use of the 4D tablet?

      The tablet is a combination anti-tubercular medicine that helps to treat tuberculosis which is a lung disease caused by Mycobacterium tuberculosis. It stops the growth of infection causing bacteria and reduces the spread of infection.

      Q2. What are the side effects of the 4D tablet?

      The tablet is well tolerated when taken in prescribed dosage guidelines. Most common side effects include color blindness, visual impairment, pain and swelling of joints, chills, salivation, watery eyes, increased uric acid leve in blood, sweating, increased liver enzymes, rash, fever, dark colored urine, headache, loss of appetite, nausea or vomiting.

      Q3. Should we take 4D tablet with food or without food?

      The tablet should be taken on an empty stomach at least 1-2 hours before or after a meal since food decreases the absorption of the medicine.

      Q4. What are the precautions to be followed while taking the 4D tablet?

      Tell your doctor if you have an allergy to any ingredients used in the tablet. Inform your doctor about all the medicines you take to ensure that you are healthy. This medicine is contraindicated in patients with hypersensitivity to any of the components used in the tablet, optic and retrobulbar neuritis, severe hepatic impairment, acute gout, concomitant use with antiviral medications. Caution is advised among patients with ocular disease (diabetic retinopathy, cataracts), diabetes mellitus, peripheral neuropathy, renal and hepatic impairment, children, pregnancy and lactation.

      Q5. Does 4D tablet make you sleepy?

      This medicine may decrease alertness, cause impaired judgement, affect your vision and make you feel dizzy, difficulty in concentration, fatigue. Do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

      Q6. Is 4D tablet harmful? What does an overdose of 4D tablet lead to?

      The tablet is usually well tolerated when taken in the recommended dosage guidelines. Over dose of the medicine may lead to loss of vision, skin rash, peripheral neuropathy (burning or tingling sensation of hands and feet). unusual bleeding or bruising, jaundice, hepatoxicity.

      Q7. Can I take 4D tablet during pregnancy?

      This medicine is not considered safe to use in pregnant women unless the potential benefits outweigh the risks involved. Despite the fact that there are limited studies in humans, animal studies have shown no or low adverse effects on the developing baby. It is recommended that you consult your doctor before consuming this tablet./p>

      Q8. Can 4D tablet be taken without a doctor’s prescription?

      No, do not take the medicine without doctor’s prescription.

      Q9. Is it okay to drink alcohol while I am on the 4D tablet?

      Consumption of alcohol with this tablet is not recommended as it may significantly increase the side effects of the medicine like severe abdominal pain, yellowing of the skin or eyes, flushing, increased heartbeat, chest pain and low blood pressure (disulfiram reaction). If you notice any unusual or abnormal reactions after taking the medicine, report to your doctor immediately.

      Q10. How to store 4D tablet?

      Store the medicine at room temperature (20-30 degree Celsius) in a cool and dry place. Keep the tablet according to the instructions mentioned on the pack or label. Store the medicine in the container or the pack it came in, tightly closed.

      Q11. If I have trouble swallowing 4D tablet, can I mix it in water and drink it?

      This tablet is designed to be swallowed with water. If you take them in a way they weren’t intended to be used, you could experience an overdose if the active constituent enters the blood stream too quickly. Alternatively, if it enters your body too slowly, it may never achieve a high enough concentration to be completely functional.

      Q12. Can we give 4D tablet to children?

      If used according to the directions given by your doctor, it is safe to be used by children.

      Q13. By when should I start seeing the results of the 4D tablet?

      The amount of time required for this medicine to show its action is within 2-4 hours of administration.

      Q14. How long does the effect of 4D tablet last?

      The amount of time for which this medicine remains active on the body is for about 8-10 hours.

      Q15. Can we take 4D tablet daily? If yes, how many tablets can we take everyday?

      Medicines should always be taken under medical supervision. Take the medicine exactly as prescribed by your doctor: for dosage and duration. Most recommended dose is once a day.

      Q16. For how many days should I take the 4D tablet?

      The number of days that any medicine must be taken varies from patient to patient; and case to case. So always stick to your doctor’s suggestion about how many days to take this medicine.

      Q17. When should I take 4D tablet?

      Use the medicine exactly as prescribed by your doctor for the dosage and duration.

      Note: All of the above information is for reference purpose only. It is always recommended that you consult a medical professional.

      Seller Information
      Manufactured By

      NOVARTIS INDIA LTD

      inspire bkc, g block,6 & 7 floor, bkc main road,,bandra (e) mumbai 400051

      Packed By

      NOVARTIS INDIA LTD

      inspire bkc, g block,6 & 7 floor, bkc main road,,bandra (e) mumbai 400051

      Applicable Offers

      • 20% Discount
        On prescription medicines, orders above Rs 1000 T & C

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