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Ano Metrogyl Cream 20gm
Uses and Benefits

Uses and Benefits

Ano Metrogyl Cream 20gm is a combination of 3 drugs used to treat anorectal pain or itching and also to treat a wide variety of wounds. However, the uses mentioned here are not exhaustive. There may be other conditions for which this medication may be used upon doctor’s discretion.

Composition

Composition

The active ingredients of Ano Metrogyl Cream 20gm are Lignocaine or Xylocaine or Lidocaine 4%w/w, Metronidazole 1% w/w, and Sucralfate 7% w/w.

Mechanism of Action of Drugs

Mechanism of Action of Drugs

Lignocaine also is known as Lidocaine or Xylocaine. It is a local anesthetic which works by blocking the pathway of pain signals by withholding the NA movement entering the nerve endings at the site of pain.

Metronidazole is a biologically inactive compound which can be metabolized in the body (prodrug) to produce its effect. This acts by withholding the bacterial nucleic acid synthesis and helps in the ramification of bacterial cell death.

Sucralfate is used as an anesthetic and also helps to form a protective barrier at wound sites by adhering to wound proteins.

Contraindications and Cautions

Contraindications and Caution

Patients with the following conditions are suggested to seek advice from their health care professionals before using the Ano Metrogyl Cream 20gm:

  • Hypersensitivity to any of the ingredients used in the Ano Metrogyl Cream 20gm such as Lignocaine, Metronidazole and Sucralfate
  • Disulfiram use within any 14 days
  • Broken or inflammed skin
  • Treatment site infection
  • Caution:
  • Cockayne syndrome
  • CNS disorder
  • Blood dyscrasia
  • Hepatic impairment
  • Hepatic impairment
  • Sepsis
  • Shock (Severe)
  • Heart block
  • Rash
  • Skin temperature increased
  • Acutely ill or debilitated patients
Side Effects

Side and Adverse Effects

The following side effects may or may not occur during the usage of Ano Metrogyl Cream 20gm. It is generally well tolerated when taken in the prescribed dosage guidelines. More common ones are generally mild and may include:

  • Nausea
  • Vomiting
  • Epigastric discomfort
  • Abdominal cramps
  • Diarrhea
  • Headache
  • Dizziness
  • Dark red-brown urine
  • Candidiasis
  • Drowsiness
  • Pruritus
  • Skin rash

Rare but more serious adverse effects may include:

  • Seizures
  • Aseptic meningitis
  • Peripheral neuropathy
  • Optic neuropathy
  • Encephalopathy
  • Stevens-johnson syndrome
  • Leukopenia
  • Thrombocytopenia
  • Carcinogenicity
  • Pancreatitis
How to Use

How to Use

Do not exceed the dose prescribed by your doctor. Wash your hands the the rectum well, before use. Apply a thin film of Ano Metrogyl Cream 20gm to the rectum or anus part when pain arrives or follow the directions given by your physician. Ensure that you wash your hands after the application as well – avoid the contact of the medicine with the eyes since the contact of it with the eyes may cause irritation or burning sensation in the eyes.

Overdosage

Avoid taking more than the prescribed dosage. In case of an accidental overdose, look for any new symptoms. If you observe any, promptly seek medical advice or report it to the near by poison control centre.

Warnings and Precautions

Warnings and Precautions

Take Ano Metrogyl Cream 20gm only on the advice of a medical practitioner. Dosage adjustment or complete avoidance of the medication may be required in the following conditions:

Liver:

Inform your doctor if you have any hepatic problems before using the cream.

Pregnancy:

Do not take this medicine without talking to your doctor if you are pregnant or planning to become pregnant.

Lactation:

Consult your doctor before breastfeeding an infant because it is not known whether this drug may harm an breastfed infant are not.

Drug Interactions:

Caution always advised when used with other medicines such as over the counter medicines, herbal supplements, and vitamins. Tell your doctor the medicines which you are currently using or which you start or stop.

Precautions
  • Keep this medication out of sight and reach of children.
  • Store in a cool and hygienic place, away from heat and moisture.
  • Do not use the medicine beyond its expiry date.
  • Recap the cream after its use.
FDA Pregnancy Category

FDA Pregnancy Category

Category B: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.


Drug Composition information
Therapeutic Classification

Anaesthetics- Local & General

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