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MRP 55

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BIORAN 15GM GEL

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Delivery by Nov 30, 2020

BIORAN 15GM GEL
Bioran Gel 15gm
Uses and Benefits

Uses and Benefits

Bioran Gel 15gm is a nonsteroidal anti-inflammatory drug (NSAID) gel used for the topical application used in the treatment and prevention of pains such as osteoarthritis, backache, musculoskeletal pains, psoriatic arthritis, osteochondrosis with the radicular syndrome. However, the uses mentioned here are not exhaustive. There may be other conditions for which this medication may be used upon a doctor’s discretion.

Composition

Composition

The active ingredient of Bioran Gel 15gm is Diclofenac 1% w/w.

Mechanism of Action of Drugs

Mechanism of Action of Diclofenac:

Diclofenac acts by inhibiting the prostaglandin synthesis. Prostaglandins are basically compounds that get produced in huge numbers, as a response to pain, injury or infection. The large production of prostaglandins causes inflammation associated with redness, swelling, pain and fever. Thus by inhibiting their synthesis, Diclofenac treats inflammation and reduces pain.

Contraindications and Cautions

Contraindications and Caution

Patients with the following conditions are suggested to seek advice from their health care professionals before using the Bioran Gel 15gm:

  • Hypersensitivity to any of the excipients used in the Dynapar gel such as Diclofenac
  • Renal impairment
  • Hepatic impairment
  • Asthma
  • Fluid retention
  • GI bleeding
Side Effects

Side and Adverse Effects

The following side effects may or may not occur during the usage of this gel. It is generally well tolerated when applied in the prescribed dosage guidelines. More common ones are generally mild and may include:

  • Diarrhea
  • Constipation
  • Rash
  • Drowsiness

Rare but more serious adverse effects may include:

  • Irritability
  • Blurred vision
  • Anemia
  • Exfoliative dermatitis
  • Stevens-johnson syndrome
How to Use

Wash your hands and the affected area well, before usage of the gel. Wipe dry.
Gently apply a thin layer of Bioran Gel 15gm topically on the affected area – not rub it harshly.
Contact with the eyes may cause a burning sensation. To avoid the same, wash your hands thoroughly after the application.
Dosage: 3-4 times in a day or as recommended by your doctor/healthcare professional or a pharmacist.

Overdosage

Avoid applying more than the prescribed dosage. In case of an accidental overdose, promptly seek medical advice. Depending on the dosage, symptoms may vary but you may experience anyone or more of the following signs or symptoms:

  • Lethargy
  • Drowsiness
  • Nausea
  • Vomiting
Warnings and Precautions

Pregnancy:

Do not use this medicine without informing your doctor if you are pregnant or planning to become pregnant – there are no studies on humans whether the drug may affect an unborn or not.

Lactation:

May be used while breastfeeding based on minimal maternal systemic absorption in the body.

Precautions
  • Avoid contact with eyes and mucous membrane.
  • Strictly for topical use: do not consume the gel orally.
  • Keep it away from sight and reach of children .
  • Do not apply on the open skin wounds, infections, inflammations, or exfoliative dermatitis.
FDA Pregnancy Category

FDA Pregnancy Category

Category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


Drug Composition information
What is Diclofenac for:

This medication is an NSAID, prescribed for severe pain. This medication decreases the hormones that cause inflammation and pain in the body.

How does Diclofenac work:

Diclofenac blocks chemicals that cause pain and swelling.

How should Diclofenac be used:

PO- The recommended dosage is 100-200 mgday in divided doses.Topical- Apply the gel (4 g) to the affected area, 4 times daily. It comes as a tablet to take by mouth, with food.It also comes as a gel to apply topically.

Common side effects of Diclofenac :

Headache. Belly pain. Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. Hard stools (constipation). Drinking more liquids, working out, or adding fiber to your diet may help. Talk with your doctor about a stool softener or laxative. Loose stools (diarrhea). Harm to the liver may rarely happen.

What do I do if I miss a dose

Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Many times this drug is taken on an as needed basis

What precautions should I take when taking Diclofenac :

If you have an allergy to diclofenac or any other part of this drug. Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you are more than 24 weeks pregnant.

When do I need to seek medical help

If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Chest pain or pressure. Change in strength on 1 side is greater than the other, trouble speaking or thinking, change in balance, or blurred eyesight. Very upset stomach or throwing up. Very bad belly pain. Very bad swelling or pain of hands or feet. A big weight gain. Black, tarry, or bloody stools. Blood in the urine. Very loose stools (diarrhea). Not able to eat. Any bruising or bleeding. Yellow skin or eyes. Any rash. Side effect or health problem is not better or you are feeling worse.

Can I take Diclofenac with other medicines:

Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.

Are there any food restrictions

Avoid Alcohol

How do I store Diclofenac :

Store it at room temperature and in an airtight container. Keep away from excess heat and moisture.

Pregnancy Category

Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Therapeutic Classification

Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) , Non-Opioid Analgesics & Antipyretics

Applicable Offers

  • 20% Discount
    On prescription medicines, orders above Rs 1000 T & C
  • 10% Discount
    On prescription medicines, orders above Rs 200 T & C
  • MedPlus Wallet
    20% Instant Discount MedPlus Wallet T & C

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