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CALPOL T TAB

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MRP 76.85

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15 Units/pack

CALPOL T TAB
Calpol T Tablet
Uses and Benefits

Uses and Benefits

Calpol T Tablet is most commonly used to treat fever and mild to moderate and moderately severe chronic pains such as muscle ache, headache, toothache, arthritis, backache, menstrual cramps, postoperative and post-immunization pyrexia. However, the uses mentioned here are not exhaustive. There may be other conditions for which this medication may be used upon doctor’s discretion.

Composition

Composition

The active ingredients of Calpol T Tablet are Paracetamol (also known as Acetaminophen) 325mg and Tramadol 37.5mg.

Mechanism of Action of Drugs

Mechanism of Action of Drugs

Paracetamol (or Acetaminophen) primarily acts as an analgesic and antipyretic agent. Further, it also has anti-inflammatory properties to a certain extent. It produces an analgesic effect by increasing pain threshold and antipyresis by acting on the hypothalamic heat-regulating center.

Tramadol linked with the group of drugs called opioid analgesics acts on the sites of CNS to block or inhibit the transmission of pain signals.

Contraindications and Cautions

Contraindications and Caution

Patients with the following conditions are suggested to seek advice from their health care professionals before taking the Calpol T Tablet:

  • Hypersenstivity to any of the components used in the Calpol T Tablet such as Paracetamol (Acetaminophen) and Tramadol
  • Uncontrolled epilepsy
    Acute or severe bronchial asthma
    Severe renal and hepatic impairment

Caution:

  • Hepatic impairment
  • Malnutrition
  • Hypovolemia
  • Chronic alcohol use
Side Effects

Side and Adverse Effects

The following side effects may or may not occur during the usage of this tablet. It is generally well tolerated when taken in the prescribed dosage guidelines. More common ones are generally mild and may include:

  • Nausea
  • Skin rash
  • Tinnitus
  • Dryness of mouth
  • Decreased appetite
  • Mouth ulcer
  • Gastric problems
  • Palpitation
  • Dizziness
  • Headache
  • Abdominal discomfort
  • Asthenia
  • Diarrhea
  • Flatulence
  • Depression
  • Dysphoria
  • Coordination disturbance
  • Allergic reaction
  • Pruritus
  • Dermatitis
  • Angioedema

Rare but more serious adverse effects may include:

  • Thrombocytopenia
  • Hypokalemia
  • Anemia
  • Hepatotoxicity
  • Anaphylaxis
  • Renal tubular necrosis, acute
  • Respiratory depression
  • Seizures
  • Cognitive dysfunction
  • Hallucinations
  • Toxic epidermal necrolysis
  • Vasodilation
  • Orthostatic Hypotension
  • Steven-Johnson syndrome
  • Syncope
  • Menstrual disorde
  • Tachycardia
  • Peripheral ischemia
  • Menopausal symptoms
  • Micturition difficulty
  • Haematuria
How to Use

How to Use

Do not exceed the dose prescribed by your doctor. Swallow the tablet whole, immediately after opening the tablet from the strip. Do not break or chew the Calpol T Tablet whole.
Avoid missing or forgetting a dose. If you do, take it as soon as you remember; but if it is time for your next dose, skip it and take it according to your normal schedule. Do no swallow two doses at the same time which is dangerous to your health.
Take Calpol T Tablet with or without food preferably after food to avoid GI disturbance.
Take the dosage as recommended by your doctor.
For children talk to your doctor before giving Calpol T Tablet.

Overdosage

Avoid taking more than the prescribed dosage. In case of an accidental overdose, promptly seek medical advice. Depending on the dosage, symptoms may vary but you may experience one or more of the following signs or symptoms:

  • Abdominal pain
  • Yellow skin
  • Blood clotting
  • Confusion
  • Hypoglycemia
  • Miosis
  • Vomiting
  • Cold and Clammy skin
  • Cardiac collapse
  • Coma
  • Lactic acidosis
  • Cardiac arrest
  • Lethargy
  • Flaccid skeletal muscle
  • Hypotension
Warnings and Precautions

Warnings and Precautions

Take Calpol T Tablet only on the advice of a medical practitioner. Dosage adjustment or complete avoidance of the medication may be required in the following conditions:

Kidney:

Caution advised among people with renal problems. If you have any, it is highly recommended that you consult your doctor before the consumption of this medicine.

Liver:

Caution advised among people with hepatic problems. If you have any, it is highly recommended that you consult your doctor before the consumption of this medicine.

Pregnancy:

Paracetamol: This drug may be used during pregnancy, no known risk of fetal harm. However, consider taking the tablet if suggested by a doctor.
Tramadol: Do not take this medicine if you are pregnant or planning to get pregnant because this drug crosses through the blood-brain barrier and there is a risk of fetal harm. However, do not take the medicine until unless suggested by a doctor.

Lactation:

Paracetamol: This may be used while breastfeeding, no known risk of infant harm based on human data and there are no human studies are available to estimate effects on milk production.
Tramadol: Do not take this medicine if you are a nursing mother, it is expected that this medicine may pass into breast milk and harm a breastfed infant.

Alcohol:

Do not take Calpol T Tablet along with alcohol as it may increase the hepatic risk.

Drug Interactions:

Affected by delayed gastric emptying, analgesic-associated nephropathy, methemoglobinemia, carbamazepine along with tramadol may reduce the analgesic effect of tramadol. Caution advised with serotonin syndrome risk, CYP2D6 inhibitors, and CYP3A4 inhibitors.

Precautions
  • Keep the medicine out of sight and reach of children.
  • Keep the medicine in a cool and neat place, away from heat and moisture.
  • Do not use the medicine beyond its expiry.
  • Do not use the medicine if the tablet strip is torn or the tablet is broken.
  • Do not use this medicine with other paracetamol containing medicines.
FDA Pregnancy Category

FDA Pregnancy Category

Category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


Drug Composition information
What is Paracetamol for:

It is used to used to relieve mild to moderate pain and to reduce fever.

How does Paracetamol work:

Paracetamol blocks chemicals that cause pain. It lowers fever by changing the bodys thermostat in the brain.

How should Paracetamol be used:

Take this as directed by your doctor. Do not take more than instructed by your doctor. Never take more than 1000 mg at any one time and no more than 4 times in one day. The dose for a child is different from the adult dose. Be sure to check with your doctor or pharmacist before giving this medicine to a child. It may be taken with or without food. If you need pain relief fast, take it on an empty stomach as food may slow down the absorption. You may stop taking it when you have no more pain or fever. Take it only when you need to.

Common side effects of Paracetamol :

Upset stomach or throwing up. Harm to the liver may rarely happen.

What do I do if I miss a dose

Many times this drug is taken on an as needed basis.

What precautions should I take when taking Paracetamol :

Do not take this drug if you had an allergy to this or similar drugs in the past. Do not take it if you have liver or kidney failure.

When do I need to seek medical help

Seek help if you are having an allergic reaction to the drug. Signs include rash, difficulty breathing, swelling of the lips, face, tongue; or hives. Symptoms of an overdose may include nausea; vomiting; loss of appetite; sweating; extreme tiredness; unusual bleeding or bruising; pain in the stomach; yellowing of the skin. Contact an emergency centre immediately if you suspect overdose.

Can I take Paracetamol with other medicines:

Alert your doctor if you are taking blood-thinning medicines such as warfarin.

Are there any food restrictions

Avoid Alcohol

How do I store Paracetamol :

Store in a cool, dry place away from the reach of children. - Medicines must not be used past the expiry date.

Pregnancy Category

Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Therapeutic Classification

Non-Opioid Analgesics & Antipyretics

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