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Combiflam Icyhot 55Gm Spray

Country of origin: INDIA

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MRP 192.48

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Combiflam Icyhot 55Gm Spray

Combiflam ICYHOT Spray 55gm
Uses and Benefits

Uses and Benefits

Combiflam ICYHOT Spray 55gm is a non-steroidal anti-inflammatory drug (NSAID) medication for topical application. This Spray is used in the treatment and prevention of pains such as osteoarthritis, backache, musculoskeletal pains, psoriatic arthritis, and osteochondrosis with the radicular syndrome. However, the uses mentioned here are not exhaustive. There may be other conditions for which this medication may be used upon a doctor’s discretion.



The active ingredients of Combiflam ICYHOT Spray 55gm are Diclofenac 1.16% w/w, Linseed Oil 3% w/w, Menthol 5% w/w, and Methyl Salicylate 10% w/w.

Mechanism of Action of Drugs

Mechanism of Action of Drugs

Diclofenac acts by inhibiting both leukocyte migration and the enzyme cyclooxygenase (cox-1 and cox-2) leading to the peripheral inhibition of prostaglandin synthesis. Prostaglandins areĀ  compounds which basically activate pain receptors. Thus, when Diclofenac inhibits the synthesis of prostaglandins, the analgesic effect of Diclofenac has been produced.

Linseed oil diminishes skin rashes, skin irritation, and redness.

On the other hand, Menthol provides a cooling effect on the skin, post-application.

Lastly, Methyl Salicylate works by giving a temporary analgesic effect.

Contraindications and Cautions

Contraindications and Caution

Patients with the following conditions are suggested to seek advice from their health care professionals before using the Spray:

  • Hypersensitivity to any of the components used in the Combiflam ICYHOT Spray 55gm such as Diclofenac, Linseed, Menthol, and Methylsalicylate
  • Caution:
  • Renal impairment
  • Hepatic impairment
  • Asthma
  • Fluid retention
  • GI bleeding
Side Effects

Side and Adverse Effects

The following side effects may or may not occur during the usage of this Combiflam ICYHOT Spray 55gm. It is generally well tolerated when used in the prescribed dosage guidelines. More common ones are generally mild and may include:

  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Rash
  • Drowsiness

Rare but more serious adverse effects may include:

  • irritability
  • Blurred vision
  • Anemia
  • Exfoliative dermatitis
  • Stevens-johnson syndrome
How to Use

How to Use

Wash your hands as well as the affected area well, before the application. Wipe dry. Shake and press the spray gently on the affected area. Contact with the eyes may cause irritation or burning sensation. Hence, to avoid this, wash your hands well, post-application as well.

Do not spray on the broken,damaged or on open wounds.
Use the spray whenever required (SOS).


Avoid using more than the prescribed dosage. In case of an accidental overdose, promptly seek medical advice. Depending on the dosage, symptoms may vary but you may experience one or more of the following signs or symptoms:

  • Lethargy
  • Drowsiness
  • Nausea
  • Vomiting
Warnings and Precautions

Warnings and Precautions

Apply Combiflam ICYHOT Spray 55gm only on the advice of a medical practitioner. Dosage adjustment or complete avoidance of the medication may be required in the following conditions:

Drug Interactions:

Caution always advised when used with other medicines especially when used with other creams, ointments, and Sprays, etc.

  • Avoid contact with eyes and mucous membrane.
  • Strictly for topical use: do not consume the Spray orally.
  • Keep it away from sight and reach of children.
  • Do not apply on the open skin wounds, infections, inflammations, or exfoliative dermatitis.
  • Do not use the medicine beyond its expiry.
FDA Pregnancy Category

FDA Pregnancy Category

Category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant the use of the drug in pregnant women despite potential risks.

Seller Information
Manufactured By


gala no 3,4,5,6b & 6c,7f city link warehsg,complex building no 120-121 vill.vadpe bhiwandi-thane 421302,mahrashtra,india

Packed By


gala no 3,4,5,6b & 6c,7f city link warehsg,complex building no 120-121 vill.vadpe bhiwandi-thane 421302,mahrashtra,india

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