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Deriphyllin OD Tablet 450mg
Uses and Benefits

Uses and Benefits

Deriphyllin OD Tablet 450mg is used to treat asthma, acute bronchospasm, and chronic bronchospasm. It helps relieve wheezing, emphysema and other respiratory problems. However, the uses mentioned here are not exhaustive. There may be other conditions for which this medication may be used upon doctor’s discretion.



The active ingredients of Deriphyllin OD Tablet 450mg are Etofylline 346mg and Theophylline 104mg.

Mechanism of Action of Drugs

Mechanism of Action of Drugs

Etofylline is used to treat asthma and chronic obstructive pulmonary diseases.

Theophylline is used as a bronchodilator which helps by relaxing the muscles in chest, lungs and reduces the sensitivity in the lungs to allergens and other sources of bronchospasm.

Contraindications and Cautions

Contraindications and Caution

Patients with the following conditions are suggested to seek advice from their health care professional before taking the Tablet:

  • Hypersensitivity to any of the ingredients used in the Tablet such as Etofylline and Theophylline
  • Caution:
  • PUD active
  • Seizure disorder
  • Arrhythmias
  • Pulmonary edema, acute
  • Cor pulmonale
  • Hepatic impairment
  • Hypothyroidism
  • Febrile
  • Sepsis with multi-organ failure
  • Shock
  • Smoking habit changes
  • Neonates in infants
Side Effects

Side and Adverse Effects

The following side effects may or may not occur during the usage of Deriphyllin OD Tablet 450mg. It is generally well tolerated when taken in the prescribed dosage guidelines. More common ones are generally mild and may include:

  • Nausea
  • Vomiting
  • Headache
  • Insomnia
  • Diarrhea
  • Irritability
  • Restlessness
  • Tremor
  • Diuresis, transient

Rare but more serious adverse effects may include:

  • Arrhythmias
  • Hypotension
  • Shock
  • Exfoliative dermatitis
How to Use

How to Use

Do not exceed the dose prescribed by your doctor. Swallow the Deriphyllin OD Tablet 450mg whole, immediately after opening the tablet from the strip. Do not break/crush/ chew the tablet.

Avoid missing or forgetting a dose. If you do, take it as soon as you remember; but if it is almost time for your next dose, skip it and take it according to your normal schedule. Don’t consume two doses at the same time which is dangerous to your health.

Take the Deriphyllin OD Tablet 450mg with or without food. May be taken with meals to reduce GI discomfort. Take the Deriphyllin OD Tablet 450mg at the prescribed time and dosage.


Avoid taking more than the prescribed dosage. In case of an accidental overdose, promptly seek medical advice. Depending on the dosage, symptoms may vary but you may experience one or more of the following signs or symptoms:

  • Tachycardia
  • Fever
  • Anorexia
  • Nausea
  • Occasional vomiting
  • Diarrhea
  • Insomnia
  • Irritability
  • Restlessness
  • Agitated maniacal behavior
  • Extreme thirst
  • Tinnitus
  • Palpitations
  • Arrhythmias
  • Delirium
  • Muscle twitching
  • Severe dehydration
  • Albuminuria
  • Emesis of coffee ground material
  • Hyperthermia
  • Profuse Diaphoresis
  • Seizures result in death
Warnings and Precautions

Warnings and Precautions

Take Deriphyllin OD Tablet 450mg only on the advice of a medical practitioner. Dosage adjustment or complete avoidance of the medication may be required in the following conditions:


Caution advised among people with hepatic problems. If you have any, it is highly recommended that you consult your doctor before the consumption of this Deriphyllin OD Tablet 450mg.


Do not take the medicine if you are pregnant or likely to get pregnant because safety during pregnancy is unknown. However, consider taking the tablet if suggested by a healthcare professional.


Inform your doctor if you are a nursing mother because safety during lactation has not yet established.


Increased renal clearance with alcohol.


Decreased absorption of drug with food.

Drug Interactions:

Caution always advised when used with other medication. Therefore, inform your doctor about your current list of medication which you start or stop.

  • Keep the Deriphyllin OD Tablet 450mg out of sight and reach of children.
  • Store at 20-250C away from heat and moisture.
  • Do not use Deriphyllin OD Tablet 450mg beyond its expiry.
  • Do not accept the torn strip or a broken tablet.
FDA Pregnancy Category

FDA Pregnancy Category

Category N: No information available.

Drug Composition information
What is Theophylline for:

This medication is a bronchodilator, prescribed for asthma, chronic bronchitis, emphysema, and other lung diseases. It works by relaxing the muscle around the airways in the lungs.

How does Theophylline work:

Theophylline calms lung muscles. It protects the airways from irritants. It makes the diaphragm stronger.

How should Theophylline be used:

It comes as a tablet and capsule to take by mouth with or without food. The recommended dose is 400 or 600 mg once a day in the morning or evening.

Common side effects of Theophylline :

Nervous and excitable. Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

What do I do if I miss a dose

Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.

What precautions should I take when taking Theophylline :

If you have an allergy to theophylline or any other part of this drug. Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.

When do I need to seek medical help

If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. A fast heartbeat. Very bad dizziness or passing out. Very nervous and excitable. Very upset stomach or throwing up. Peak flow measurement low. Any rash. Side effect or health problem is not better or you are feeling worse.

Can I take Theophylline with other medicines:

Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.

Are there any food restrictions

Avoid Alcohol. Avoid taking large amount of caffeinated beverages. It may affect blood sugar level; monitor sugar level regularly while taking this medication.

How do I store Theophylline :

Store in a cool, dry place away from the reach of children. - Medicines must not be used past the expiry date.

Pregnancy Category

Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Therapeutic Classification

Antiasthmatic & COPD Preparations

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