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ECOSPRIN GOLD 10MG CAP

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MRP 89.72

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15 Units/pack

ECOSPRIN GOLD 10MG CAP
Ecosprin Gold Capsule 10mg
Uses and Benefits

Uses and Benefits

Ecosprin Gold Capsule 10mg is used in the treatment of mild to moderate pain and fever (for temporary relief) and also in relieving from pain and inflammation associated with musculoskeletal and joint disorders, juvenile rheumatoid arthritis. This capsule also helps to reduce clots in the blood vessels, reduces bad cholesterol in the body and risk of death or nonfatal myocardial infarction in patients with preceding infarction or unstable angina pectoris (chest pain). However, the uses mentioned here are not exhaustive. There may be other conditions for which this medication may be used upon doctor’s discretion.

Composition

Composition

The active ingredients of Ecosprin Gold Capsule 10mg are Atorvastatin 10mg, Clopidogrel 75mg and Aspirin (also known as Acetylsalicylic Acid ASA)) 75mg.

Mechanism of Action of Drugs

Mechanism of Action of Drugs

Atorvastatin helps to reduce bad cholesterol LDL and raises the good cholesterol HDL in the body.

Clopidogrel withholds the binding of ADP to platelet P2Y12; thus reducing the platelet aggregation and as a result, prevents blood clots.

With its analgesic, anti-inflammatory, antipyretic and anti-platelet properties, Aspirin irreversibly withholds cyclooxygenase, reduces thromboxane A2 and prostaglandin synthesis. Prostaglandins are the components responsible for inflammation, pain and platelet aggregation. Thus by reducing the synthesis of these, the inflammation is controlled.

Contraindications and Cautions

Contraindications and Caution

Patients with the following conditions are suggested to seek advice from their health care professionals before taking Ecosprin Gold Capsule 10mg:

  • Hypersensitivity to any of the ingredients used in the Ecosprin Gold capsule such as Atorvastatin, Clopidogrel, and Aspirin or Acetylsalicylic acid(ASA)
  • ASA or NSAID induced asthma or urticaria
  • GI Bleeding
  • Coagulation disorder
  • G6PD deficiency
  • HTN Uncontrolled
  • Caution:
  • Thrombocytopenia
  • Surgery or trauma
  • Intracranial lesion
  • GERD
  • Gout
  • Renal impairment
  • Hepatic impairment
  • Sodium restriction
  • PUD
  • Diabetes mellitus
  • Hypothyroidism
  • Ocular disease
  • GI Disorder
  • Elective surgery within 5 days
  • Rauma
  • Mod severe renal impairment
Side Effects

Side and Adverse Effects

The following side effects may or may not occur during the usage of this Ecosprin Gold Capsule 10mg. It is generally well tolerated when taken in the prescribed dosage guidelines. More common ones are generally mild and may include:

  • Dyspepsia
  • Nausea
  • Vomiting
  • Abdominal Pain
  • Tinnitus
  • Dizziness
  • Hyperuricemia
  • Bleeding
  • Ecchymosis
  • Constipation
  • Diarrhea
  • Headache
  • Arthritis
  • Diarrhea
  • Extremity pain
  • Muscle spasms
  • Flatulence
  • Insomnia
  • Urticaria
  • Myalgia
  • Cognitive impairment

Rare but more serious adverse effects may include:

  • Anaphylaxis reaction
  • Angioedema
  • Bronchospasm
  • Bleeding severe
  • GI perforation
  • Ulcer
  • DIC
  • Pancytopenia
  • Thrombocytopenia
  • Agranulocytosis
  • Aplastic anemia
  • Hypoprothrombinemia
  • Nephrotoxicity
  • Hepatotoxicity
  • Salicylism
  • Reye syndrome
  • Tendon rupture
  • Acute renal failure
  • Hepatotoxicity
  • Photosensitivity
  • Stevens-johnson syndrome
  • Leukopenia
  • TTP
  • Erythema multifome
  • Stevens-johnson syndrome
  • Toxic epidermal necrolysis
How to Use

How to Use

Do not exceed Ecosprin Gold Capsule 10mg dose prescribed by your doctor.
Swallow Ecosprin Gold Capsule 10mg whole, immediately after opening the capsule from the strip. Do not break/cut/chew Ecosprin Gold Capsule.
Avoid missing a dose. If you do, take it as soon as you remember; but if it is time for your next dose, skip it and take it according to your normal schedule. Don’t swallow two doses at the same time which is dangerous to your health.
Ecosprin Gold capsule 10mg may be taken with food.
Dosage as directed by your physician or follow the instructions given on the prescription.

Overdosage

Avoid taking more than the prescribed dosage. In case of an accidental overdose, seek prompt medical advice. Depending on the dosage, symptoms may vary but you may experience one or more of the following signs or symptoms:

  • Hyperventilation
  • Fever
  • Restlessness
  • Coma
  • CV collapse
  • Respiratory failure
  • Prolonged bleeding
  • Bleeding complications
Warnings and Precautions

Warnings and Precautions

Take Ecosprin Gold Capsule only on the advice of a medical practitioner. Dosage adjustment or complete avoidance of the medication may be required in the following conditions:

Kidney:

Inform your doctor if you have any renal issues, before taking Ecosprin Gold Capsule 10mg.

Liver:

Inform your doctor if you have any hepatic problems, before taking the Ecosprin Gold capsule.

Pregnancy:

Atorvastatin: Do not use this medicine during pregnancy. There have been noted chances of teratogenicity based on limited or conflicting human data and also delayed fetal development based on mechanism of action of the drug.
Clopidogrel: There are no risks noted based on animal data and limited human data. Hence it may be used during pregnancy. However, there is a noted risk of maternal hemorrhage based on the mechanism of action of drugs.
Aspirin: May be used during pregnancy. However, avoid taking a high dose in 3rd trimester. No risks have been observed in case of low dose aspirin.

Lactation:

Atorvastatin: There are no human data available to evaluate risks on breastfed infants nor is there any information available to evaluate effects of the medicine on milk production. Hence, to be on the afer side, it is suggested that you consider an alternative.

Clopidogrel: Caution advised during lactation – risks are low based on drug properties and limited human data. And, no human data available to evaluate effects on milk production.
Aspirin: No risk noted when used in moderation. Therefore, the medicine may be used during breastfeeding an infant. However, there could possibly be a risk factor attached when consumed in high doses – thus it is recommended to look for an alternative for analgesic use. In any case, no human data is available to evaluate effects on milk production.

Alcohol:

Avoid drinking alcohol which may lead to risk of stomach or intestinal bleeding.

Food interactions:

Foods which are rich in vitamins may increase urinary excretion. And grape fruit juice may increase risk of myopathy or rhabdomyolysis.

Drug Interactions:

Vericella vaccine live, Dichlorphenamide, Ketorolac, Influenza nasal vaccine live, apart from it alcohol, corticosteroids, analgin, Phenylbutazone and Oxyphenbutazone, Oxyphenbutazone may increase risk of GI ulceration.
And also improves myopathy and rhabdomyolysis with itraconazole, clarithromycin, fenofibrate, cholchicines, fixed combination of lopinavir/ritonavir, may significantly increase AUC and peak plasma concentration of digoxin and increased AUC for norethindrone and ethinyl estradiol, and Increased risk of GI Bleeding when used with anticoagulants, other anti-platelets, NSAID’s, SSRI’s, and lastly Anti-platelet effect may get reduced when used with Esomeprazole and Omeprazole.

Precautions
  • Keep the medicine out of sight and reach of children.
  • Keep the medicine in a dry and hygienic place away from moisture and heat.
  • Do not use the medicine beyond its expiry.
    Do not use the Ecosprin Gold Capsule 10mg if the strip is torn or the capsule is broken.
FDA Pregnancy Category

FDA Pregnancy Category

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Drug Composition information
What is Aspirin for:

It is used to reduce fever and to relieve mild to moderate pain. It is used to relieve symptoms of rheumatoid arthritis, osteoarthritis, SLE and certain other rheumatological and immune conditions. It is used to prevent heart attacks. It is used to reduce the risk of death in people who are experiencing or recently experienced a heart attack. It is used to prevent certain kinds of strokes (Brain strokes).

How does Aspirin work:

It works by stopping the production of certain natural substances that cause fever, pain, and swelling (Inflammation). It prevents clots by reducing the stickiness of platelets.

How should Aspirin be used:

Take aspirin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Swallow the extended release tablets whole with a full glass of water. Do not break, crush, or chew them. Swallow the tablets with a full glass of water.

Common side effects of Aspirin :

Nausea, vomiting, stomach pain, heartburn

What do I do if I miss a dose

Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses.

What precautions should I take when taking Aspirin :

Tell your doctor if you are allergic to aspirin, other medications for pain and fever, dye, or any other medications. If you are taking aspirin on a regular basis to prevent heart attack or stroke, do not take ibuprofen to treat pain or fever without talking to your doctor. Tell your doctor if you ever had asthma, heartburn, anemia, bleeding problems, kidney or liver disease. Tell your doctor if you are pregnant or if you are having surgery including dental procedures.

When do I need to seek medical help

Seek help if you think there was an overdose or signs of a very bad reaction to the drug. These include wheezing, chest tightness, fever, itching, bad cough, blue or gray skin color, seizures, or swelling of face, lips, tongue, or throat. Seek help is a side effect or health problem is not better or you are feeling worse.

Can I take Aspirin with other medicines:

Sometimes drugs are not safe when you take them with certain other drugs and food. Taking them together can cause bad side effects. Be sure to talk to your doctor about all the drugs you take.

Are there any food restrictions

Avoid Alcohol

How do I store Aspirin :

Store in a cool, dry place away from the reach of children. - Medicines must not be used past the expiry date.

Pregnancy Category

Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Therapeutic Classification

Anticoagulants and Antiplatelets

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