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Country of origin: INDIA

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MRP 8.60

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ABZ 400MG TAB

ABZ 400Mg tablet
Uses and Benefits

Uses and Benefits

ABZ 400Mg tablet is an antiparasitic medication used in the treatment and prevention of parasitic infections caused by tapeworms, pinworms, roundworms and hookworms. It is used in treating serious infections of the gastrointestinal tract, liver, heart, lungs, bones, genital areas, skin, joints and other areas of the body caused by susceptible anaerobic bacteria. It is prescribed in treating trichomoniasis in both males and females, giardiasis, amoebic dysentery, anaerobic bacterial infection, antibiotic associated pseudomembranous colitis and in helicobacter pylori eradication therapy. However, the uses of this tablet mentioned here are not comprehensive, there may be other conditions for which the medication may be used upon your doctor’s discretion.

Composition

Composition

The active ingredient of ABZ 400Mg tablet is Albendazole 400Mg

Mechanism of Action of Drugs

Mechanism of Action of Drugs

Albendazole works by inhibiting the growth of bacteria, protozoa and other microorganisms that cause infections by damaging their DNA and disrupts certain vital functions in the worm’s body, thus resulting in draining the worm’s energy, eventually killing it.

Contraindications and Cautions

Contraindications and Caution

Patients with following conditions are suggested to seek advice from their healthcare professionals before using ABZ tablet:

  • Hypersensitivity to Albendazole and other nitroimidazoles
  • Concomitant use with disulfiram within the last 14 days
  • Pregnancy (1st trimester)
  • Caution:
  • History of seizure disorders
  • Colitis
  • Retinal damage
  • Neurologic toxicity
  • Blood dyscrasias
  • Cockayne syndrome
  • Hepatic impairment
  • Severe renal impairment or End stage renal disease
  • Pregnancy and lactation
Side Effects

Side and Adverse Effects

The following side effects may or may not occur during the usage of this tablet. ABZ 400Mg tablet is usually well tolerated when taken in the prescribed dosage guidelines. Most of the side effects are generally mild and you may experience one or more of the following symptoms:

  • Nausea
  • Vomiting
  • Difficulty in breathing
  • Epigastric discomfort
  • Abdominal cramps
  • Diarrhea
  • Headache
  • Dizziness
  • Dry mouth
  • Dark red-brown urine
  • Candidiasis
  • Weight loss
  • Difficulty in swallowing
  • Joint or muscle pain

Rare but more serious adverse effects may include:

  • Seizures
  • Peripheral and optic neuropathy
  • Aseptic meningitis
  • Hair loss or thinning of the hair
  • Sore throat and hoarseness
  • Blood dyscrasias
  • Peeling or blistering of skin
  • Toxic epidermal necrolysis
How to Use

How to Use

Take ABZ 400Mg tablet as instructed by your doctor. Take the tablet soon after opening it from the strip. Don’t break or crush chew the tablet.
Avoid missing or forgetting the dose. If you do, take it as soon as you remember; but if it’s almost time for your next dose, skip it and take it according to your normal schedule. Don’t swallow two doses at the same time which is dangerous to your health.
The tablet is best taken with or immediately after food. Take the tablet at the same time every day as it helps to maintain a consistent level of medicine in the body.
Do not change the dose or stop taking the medicine before completion of the course or without consulting your doctor. Continue to use this drug until completion of the maximum amount suggested even though the symptoms disappear after the medicine has begun. Stopping the medication too early can allow the growth of the bacteria to begin, which can lead to an infection relapse.

Overdosage

Avoid taking ABZ 400Mg tablet more than the prescribed dosage. In case of overdose, promptly seek medical advice. Depending on the dosage of the medicine, symptoms may vary in individuals, you may experience the following signs or symptoms:

  • Nausea
  • Vomiting
  • Increased liver enzymes
  • Ataxia
  • Slight disorientation
Warnings and Precautions

Warnings and Precautions

Use ABZ 400Mg tablet on the advice of medical practitioner. Complete avoidance of the medication may be required in the following conditions:

Kidney:

Caution is advised among patients with kidney problems. Dose adjustments of the tablet may be needed. Regular monitoring of kidney function tests is recommended while taking this tablet. If you have any renal problems, it is highly recommended that you consult your doctor before taking this medicine.

Liver:

Caution is advised among patients with liver problems. Dose adjustments of the medicine may be needed. If you have any hepatic problems, it is highly recommended that you consult doctor before the consumption of this medicine. Inform your doctor if you develop signs of jaundice like yellowing of skin and eyes, itching and clay-colored stools while taking this medicine.

Pregnancy:

ABZ 400Mg tablet is not recommended during the 1st trimester of pregnancy. Despite the fact that there are limited studies in humans, animal studies have shown adverse effects on the developing baby. It is recommended that you consult your doctor before consumption of this medicine.

Lactation:

The medicine should be used with caution during breastfeeding. There is a possible risk of infant diarrhea and oral thrush based upon the limited human data and no human data available to evaluate effects on milk production.

Alcohol:

Consumption of alcohol with ABZ tablet is not recommended for 3 days as it increases side effects such as tachycardia, dizziness, headache, nausea and vomiting. Any symptoms of abnormal reactions after taking injection should be reported to your doctor immediately.

Driving:

The medicine may decrease alertness, cause impaired judgement, affect your vision and make you feel dizzy, light headedness, so do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

Food:

Unless your doctor instructs otherwise there are no specific dietary requirements while taking this tablet.

Drug Interactions:

All medicines interact differently for person to person. Inform your doctor or pharmacist if you are taking any other medicines which includes over-the-counter drugs, herbal tonics, supplements and medicines that you buy without a prescription. Alert your doctor if you’re taking ABZ 400Mg tablet with cimetidine, dexamethasone, praziquantel, carbamazepine, atorvastatin, warfarin, ethinyl estradiol, phenytoin, digoxin, phenobarbital, ciclosporin, lithium, disulfiram.

Precautions
  • Do not use this tablet post the expiry date
  • Do not use the tablet for durations shorter or longer than suggested by your doctor
  • Store at room temperature (20-30 degree Celsius)
FDA Pregnancy Category

FDA Pregnancy Category

Category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


Drug Composition information
What is Albendazole for:

It is used to treat infections caused by worms.

How does Albendazole work:

Albendazole works to harm the worms and fight the infection.

How should Albendazole be used:

Take this exactly as directed by your doctor. Do not take more or less than instructed by your doctor. Take Albendazole at regular intervals as instructed. Do not skip any doses. Continue to take it even when you feel better. You must complete the entire course unless otherwise directed. If you do not complete the course, the infection may not clear completely. Depending on the type of infection, you may need to take Albendazole for any length of time, ranging from 1 day to 1 month. Follow your doctors instructions. Take Albendazole together with or immediately after a full meal.

Common side effects of Albendazole :

Stomach pain, nausea, vomiting, headache, dizziness, reversible hair loss.

What do I do if I miss a dose

Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. - Do not take 2 doses at the same time or extra doses.

What precautions should I take when taking Albendazole :

Alert your doctor if you are pregnant. Do not take Albendazole if you are pregnant. - It is important that you do not get pregnant while being treated with Albendazole. - You may wish to discuss birth control methods with your doctor or pharmacist, especially if you are taking Albendazole for a longer period, such as for a month. - Avoid pregnancy for at least 1 month after you stop taking Albendazole. - Alert your doctor if you are breastfeeding.

When do I need to seek medical help

Seek help if you think there was an overdose or signs of a very bad reaction to the drug. These include wheezing, chest tightness, fever, itching, bad cough, blue or gray skin color, seizures, or swelling of face, lips, tongue, or throat. - Signs of infection. These include a fever of 100.5°F (38°C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain. - Feeling very tired or weak. - Very bad belly pain. - Very bad headache. - Very upset stomach or throwing up. - Any bruising or bleeding. - Dark urine or yellow skin or eyes. - Not able to eat. - Any rash. - Side effect or health problem is not better or you are feeling worse.

Can I take Albendazole with other medicines:

Let your doctor know if you are taking a gastric medicine called cimetidine. - Always inform your doctor and pharmacist if you are taking any other medicines, including herbal tonics, supplements and medicines that you buy without a prescription.

Are there any food restrictions

Avoid Alcohol

How do I store Albendazole :

Store in a cool, dry place away from the reach of children. - Medicines must not be used past the expiry date.

Pregnancy Category

Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Therapeutic Classification

Antihelmintics


Frequently Asked Questions

Frequently Asked Questions
Q1. What is the use of the ABZ 400Mg tablet?

The tablet is an antiparasitic medication used in the treatment and prevention of parasitic infections caused by tapeworms, pinworms, roundworms and hookworms. It is used in treating serious infections of the gastrointestinal tract, liver, heart, lungs, bones, genital areas, skin, joints and other areas of the body caused by susceptible anaerobic bacteria. It is prescribed in treating trichomoniasis in both males and females, giardiasis, amoebic dysentery, anaerobic bacterial infection, antibiotic associated pseudomembranous colitis and in helicobacter pylori eradication therapy.

Q2. What are the side effects of the ABZ 400Mg tablet?

The tablet is well tolerated when taken in prescribed dosage guidelines. Most common side effects include nausea, vomiting, difficulty in breathing, epigastric discomfort, abdominal cramps, diarrhea, headache, dizziness, dry mouth, dark red-brown urine, candidiasis, weight loss, difficulty in swallowing, joint or muscle pain. Its use may also lead to extreme but uncommon side effects such as seizures, peripheral and optic neuropathy, aseptic meningitis, hair loss or thinning of the hair, sore throat and hoarseness, blood dyscrasias, peeling or blistering of skin, toxic epidermal necrolysis.

Q3. Should we take ABZ 400Mg tablet with food or without food?

The tablet is best taken with or immediately after food.

Q4. What are the precautions to be followed while taking the ABZ 400Mg tablet?

If you ever had impaired kidney function, sever liver impairment or heart disease, let your doctor know before taking this medicine. Inform your doctor about all the medicines you take to ensure that you are healthy. This medicine is contraindicated in patients with hypersensitivity to Albendazole and other nitroimidazoles, concomitant use with disulfiram within the last 14 days, pregnancy (1st trimester), Caution is advised among patients with history of seizure disorders, colitis, retinal damage, neurologic toxicity, blood dyscrasias, Cockayne syndrome, hepatic impairment, severe renal impairment or end stage renal disease, pregnancy and lactation.

Q5. Does ABZ 400Mg tablet make you sleepy?

The tablet may decrease alertness, cause impaired judgement, affect your vision and make you feel dizzy, light headedness. Do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

Q6. Is ABZ 400Mg tablet harmful? What does an overdose of ABZ 400Mg tablet lead to?

The tablet is usually well tolerated when taken in the recommended dosage guidelines. Overdose of the medicine leads to nausea, vomiting, ataxia, slight disorientation, increased liver enzymes.

Q7. Can I take ABZ 400Mg tablet during pregnancy?

The tablet is not recommended during the 1st trimester of pregnancy. Despite the fact that there are limited studies in humans, animal studies have shown adverse effects on the developing baby. It is recommended that you consult your doctor before consuming this medicine.

Q8. Can ABZ 400Mg tablet be taken without a doctor’s prescription?

No, do not take the medicine without doctor’s prescription.

Q9. Is it okay to drink alcohol while I am on the ABZ 400Mg tablet?

Consumption of alcohol with this medicine is not recommended for 3 days as it increases side effects such as tachycardia, dizziness, headache, nausea and vomiting. Any symptoms of abnormal reactions after taking the tablet should be reported to your doctor immediately.

Q10. How to store ABZ 400Mg tablet?

Store the medicine at room temperature (20-30 degree Celsius) in a cool and dry place. Keep the tablet according to the instructions mentioned on the pack or label. Store the medicine in the container or the pack it came in, tightly closed.

Q11. If I have trouble swallowing ABZ 400Mg tablet, can I mix it in water and drink it?

This tablet is designed to be swallowed with water. If you take them in a way they weren’t intended to be used, you could experience an overdose if the active constituent enters the blood stream too quickly. Alternatively, if it enters your body too slowly, it may never achieve a high enough concentration to be completely functional.

Q12. Can we give ABZ 400Mg tablet to children?

If used according to the directions given by your doctor, it is safe to be used in children.

Q13. By when should I start seeing the results of the ABZ 400Mg tablet?

The amount of time required for this medicine to show its action is 1-2 hours after administration. You will start to feel better in 2-4 days after taking the tablet.

Q14. How long does the effect of ABZ 400Mg tablet last?

The amount of time for which this medicine remains active on the body is for about 8 hours.

Q15. Can we take ABZ 400Mg tablet daily? If yes, how many tablets can we take everyday?

Medicines should always be taken under medical supervision. Take the medicine exactly as prescribed by your doctor: for dosage and duration. Most recommended dose is once a day.

Q16. For how many days should I take the ABZ 400Mg tablet?

The number of days that any medicine must be taken varies from patient to patient; and case to case. Continue to use the medicine until completion of the maximum amount prescribed, even though the symptoms disappear after Albendazole has begun. Stopping the medication too early can allow the growth of the bacteria to begin, which can lead to an infection relapse.

Q17. When should I take ABZ 400Mg tablet?

Use the medicine exactly as prescribed by your doctor for the dosage and duration.

Note: All of the above information is for reference purpose only. It is always recommended that you consult a medical professional.

Seller Information
Manufactured By

INDOCO REMEDIES LTD

at 86-a, l.b.s. marg mulund (w)mumbai 400080

Packed By

INDOCO REMEDIES LTD

at 86-a, l.b.s. marg mulund (w)mumbai 400080

Applicable Offers

  • 20% Discount
    On prescription medicines, orders above Rs 1000 T & C
  • 10% Discount
    On prescription medicines, orders above Rs 200 T & C

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