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      Country of origin: INDIA

      Seller Information

      1 Units/pack

      MRP 10.35

      Inclusive of all Taxes

      FLAT 20% OFF On bills above 1000.0
      AF 150MG TAB

      AF 150MG tablet
      Uses and Benefits

      Uses and Benefits

      AF 150MG tablet is an anti-fungal medicine used to treat infections caused by fungi and certain yeasts. It is prescribed for oropharyngeal candidiasis (fungal infection in the mouth), oesophageal candidiasis (infection of oesophagus or food pipe causing painful swallowing), vaginal candidiasis (infection causing pain, itching and burning sensation with unusual discharge in the genital organs), cryptococcal meningitis (infection that affects the delicate membrane that covers brain and spinal cord caused by Cryptococcus strain), urinary tract infection, peritonitis (fungal infection causing inflammation of thin layer of tissue that covers the inside of abdomen and most organs present in the abdomen), candidemia (a condition in which the fungus enters blood stream and from the blood to eyes, liver, brain causing invasive candidemia). It is also for treating fungal infections of fingernails and toenails. This medicine acts by stopping the growth and multiplication of these organisms. However, the uses mentioned here are not comprehensive, there may be other conditions for which the medication may be used upon your doctor’s discretion.

      Composition

      Composition

      The active ingredient of AF tablet is Fluconazole 150MG

      Mechanism of Action of Drugs

      Mechanism of Action of Drugs

      Fluconazole changes the permeability of the cell wall of the fungal cells and prevents their growth. It binds to the phospholipids of the membrane and inhibits the fungal CYP450 activity, thereby decreasing ergosterol biosynthesis that are essential for the development of the cell membrane. This results in the death of cells due to the loss of intracellular sections.

      Contraindications and Cautions

      Contraindications and Caution

      Patients with following conditions are suggested to seek advice from their healthcare professionals before using AF 150MG tablet:

      • Hypersensitivity to any of the ingredients used in the tablet and other antifungals
      • Ventricular dysfunction
      • Severe renal impairment
      • Concomitant use with QT interval prolonging drugs
      • Caution:
      • Ischaemic or valvular disease
      • Reduces gastric acidity
      • Cystic fibrosis
      • Hepatic impairment
      • Weak immune system
      • Children and elderly
      • Pregnancy and lactation
      Side Effects

      Side and Adverse Effects

      AF 150MG tablet is usually well tolerated when used in the prescribed dosage guidelines. Most side effects are temporary and usually subsides on their own. However, consult your doctor if they persist for a longer duration. You may experience one or more of the following symptoms:

      • Headache
      • Dizziness
      • Drowsiness
      • Tiredness
      • Increased blood pressure
      • Nausea, vomiting
      • Stomach pain
      • Diarrhea
      • Constipation
      • Hair loss

      Rare but more serious adverse effects may include:

      • Abnormal liver functions
      • Hypokalaemia
      • Jaundice
      • Menstrual disorder
      • Metallic taste in mouth
      How to Use

      How to Use

      Take AF 150MG tablet as instructed by your doctor. Swallow the tablet whole with water, immediately after opening it from the strip. Do not break or crush or chew the tablet.
      Avoid missing or forgetting the dose. If you do, take it as soon as you remember; but if it’s almost time for your next dose, skip it and take it according to your normal schedule. Don’t swallow two doses at the same time which is dangerous to your health.
      This tablet can be taken with or without food. Take the tablet at the same time every day as it helps to maintain a consistent level of medicine in the body.
      Do not change the dose or stop taking the medicine before completion of the course or without consulting your doctor. Continue to use this drug until completion of the maximum amount suggested even though the symptoms disappear after the medicine has begun. Stopping the medication too early can allow the growth of the fungus to begin, which can lead to an infection relapse.

      Overdosage

      Avoid taking more than the prescribed dosage. If you notice any unusual or abnormal reactions after taking the tablet, promptly seek medical attention. Depending on the dosage of AF 150MG tablet, symptoms vary in individuals, you may experience one or more of the following symptoms:

      • Short of breath
      • Cough with mucus
      • Fast heartbeats
      • Hypertension
      • Rapid weight gain
      • Sleep problems
      • Acute liver failure
      Warnings and Precautions

      Warnings and Precautions

      Use this tablet on the advice of medical practitioner. Complete avoidance of the AF tablet may be required in the following conditions:

      Kidney:

      Extreme caution is advised among people with kidney problems. Close monitoring of kidney function and adjustments of dose of the medicine may be needed based on the clinical condition of the patient. If you have any renal problems, it is highly recommended that you consult doctor before the consumption of this tablet.

      Liver:

      Caution is advised among people with liver problems. Dose adjustments of the tablet may be needed. If you have any hepatic problems, it is highly recommended that you consult doctor before the consumption of this medicine. Inform your doctor if you develop signs of jaundice like yellowing of skin and eyes, itching and clay-colored stools while taking this tablet.

      Pregnancy:

      This medicine should be used with caution during pregnancy. Despite the fact that there are limited studies in human beings, animal studies have shown harmful effects on the developing baby. It is recommended that you consult your doctor before consuming this medicine.

      Lactation:

      This medicine is not considered safe to use in nursing mothers unless the potential benefits outweigh the risks involved. Since the effect of the medicine on infants is not clearly established, we recommend that you to consult your doctor before consuming the tablet.

      Alcohol:

      Consumption of alcohol with this tablet is not recommended as it increases side effects such as gastrointestinal bleeding, dizziness, light headedness. Any symptoms of abnormal reactions after taking the tablet should be reported to your doctor immediately.

      Driving:

      This medicine may decrease alertness, cause impaired judgement, affect your vision and make you feel dizzy. Do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

      Food:

      There are no known food interactions with this medicine.

      Drug Interactions:

      Inform your doctor or pharmacist if you are taking any other medicines which includes over-the-counter drugs, herbal tonics, supplements and medicines that you buy without a prescription. Alert your doctor if you’re taking AF 150MG tablet with anti-psychotic medications (lurasidone, pimozide), cholesterol-lowering medicines (lovastatin, simvastatin), ergot medicines (methylergonovine, ergotamine), alprazolam, carbamazepine, antineoplastic agents (busulfan, vinca alkaloids) immunosuppressants (ciclosporins, tacrolimus), corticosteroids (fluticasone, dexamethasone). Avoid taking antacids within one hour or two hours after you take the tablet as few antacids can make it harder for your body to absorb the medicine.

      Precautions
      • Do not use this tablet post the expiry date
      • Do not use this medication for durations shorter or longer than suggested by your doctor
      • Store at room temperature (20-30 degree Celsius)
      FDA Pregnancy Category

      FDA Pregnancy Category

      Category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


      Drug Composition information
      What is Fluconazole for:

      This medication is an antifungal agent, prescribed for vaginal candidiasis, pneumonia, meningitis and fungal infections of the mouth, throat, liver, kidneys, heart, urinary tract and abdomen. It works by slowing the growth of fungi that cause infection.

      How does Fluconazole work:

      Fluconazole works to harm the yeast and fight the infection.

      How should Fluconazole be used:

      PO- The recommended dose range is 50-400 mg daily. It comes as a tablet to take by mouth, with or without food once a day. It also comes as eye drops to instill into affected eyes.

      Common side effects of Fluconazole :

      Headache. Belly pain. Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar- free gum may help. Loose stools (diarrhea).

      What do I do if I miss a dose

      Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.

      What precautions should I take when taking Fluconazole :

      If you have an allergy to fluconazole or any other part of this drug. Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs

      When do I need to seek medical help

      If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Very bad belly pain. Very upset stomach or throwing up. Very loose stools (diarrhea). Not able to eat. Dark urine or yellow skin or eyes. Feeling very tired or weak. For women, if you get pregnant while taking this drug. Any rash. Side effect or health problem is not better or you are feeling worse.

      Can I take Fluconazole with other medicines:

      Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.

      Are there any food restrictions

      Avoid Alcohol

      How do I store Fluconazole :

      Store it at controlled room temperature (30°C), and in an airtight container. Keep away from children.

      Pregnancy Category

      Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

      Therapeutic Classification

      Antifungals


      Frequently Asked Questions

      Frequently Asked Questions
      Q1. What is the use of the AF 150MG tablet?

      The tablet is an anti-fungal medicine used to treat infections caused by fungi and certain yeasts. It is prescribed for oropharyngeal candidiasis (fungal infection in the mouth), oesophageal candidiasis (infection of oesophagus or food pipe causing painful swallowing), vaginal candidiasis (infection causing pain, itching and burning sensation with unusual discharge in the genital organs), cryptococcal meningitis (infection that affects the delicate membrane that covers brain and spinal cord caused by Cryptococcus strain), urinary tract infection, peritonitis (fungal infection causing inflammation of thin layer of tissue that covers the inside of abdomen and most organs present in the abdomen), candidemia (a condition in which the fungus enters blood stream and from the blood to eyes, liver, brain causing invasive candidemia). It is also for treating fungal infections of fingernails and toenails. This medicine acts by stopping the growth and multiplication of these organisms.

      Q2. What are the side effects of the AF 150MG tablet?

      The tablet is well tolerated when taken in prescribed dosage guidelines. Most common side effects include headache, nausea, vomiting, dizziness, drowsiness, tiredness, increased blood pressure, abdominal pain, diarrhea, constipation, hair loss. Its use may also lead to extreme but uncommon side effects such as abnormal liver functions, yellowing of skin or eyes, loss of hearing, hypokalaemia, menstrual disorder, weight loss, chest tightness, metallic taste in mouth.

      Q3. Should we take AF 150MG tablet with food or without food?

      The tablet can be taken with or without food.

      Q4. What are the precautions to be followed while taking the AF 150MG tablet?

      If you ever had impaired kidney function, liver impairment or heart disease, let your doctor know before taking this medicine. Inform your doctor about all the medicines you take to ensure that you are healthy. Caution is advised for patients with hypersensitivity to ingredients in the tablet and other azoles, ventricular dysfunction, severe renal impairment, ischaemic or valvular disease, reduces gastric acidity, cystic fibrosis, hepatic impairment, weak immune system, children elderly, pregnancy and lactation.

      Q5. Does AF 150MG tablet make you sleepy?

      This medicine may decrease alertness, cause impaired judgement, affect your vision and make you feel dizzy. Do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

      Q6. Is AF 150MG tablet harmful? What does an overdose of AF 150MG tablet lead to?

      The tablet is usually well tolerated when taken in the recommended dosage guidelines. Over dose of the medicine may lead to short of breath, cough with mucus, fast heartbeats, hypertension, rapid weight gain, sleep problems, acute liver failure.

      Q7. Can I take AF 150MG tablet during pregnancy?

      This medicine should be used with caution during pregnancy. Despite the fact that there are limited studies in human beings, animal studies have shown harmful effects on the developing baby. It is recommended that you consult your doctor before consuming this medicine.

      Q8. Can AF 150MG tablet be taken without a doctor’s prescription?

      No, do not take the medicine without doctor’s prescription.

      Q9. Is it okay to drink alcohol while I am on the AF 150MG tablet?

      Consumption of alcohol with this tablet is not recommended as it increases side effects such as gastrointestinal bleeding, dizziness, light headedness. Any symptoms of abnormal reactions after taking the tablet should be reported to your doctor immediately.

      Q10. How to store AF 150MG tablet?

      Store the medicine at room temperature (20-30 degree Celsius) in a cool and dry place. Keep the tablet according to the instructions mentioned on the pack or label. Store the medicine in the container or the pack it came in, tightly closed.

      Q11. If I have trouble swallowing AF 150MG tablet, can I mix it in water and drink it?

      This tablet is designed to be swallowed with water. If you take them in a way they weren’t intended to be used, you could experience an overdose if the active constituent enters the blood stream too quickly. Alternatively, if it enters your body too slowly, it may never achieve a high enough concentration to be completely functional.

      Q12. Can we give AF 150MG tablet to children?

      If used according to the directions given by your doctor, it is safe to be used by children.

      Q13. By when should I start seeing the results of the AF 150MG tablet?

      The amount of time required for this medicine to show its action is not clinically determined. You will start to feel better in 2-4 days after taking the tablet.

      Q14. How long does the effect of AF 150MG tablet last?

      The amount of time for which this medicine remains active on the body is not clinically determined.

      Q15. Can we take AF 150MG tablet daily? If yes, how many tablets can we take everyday?

      Medicines should always be taken under medical supervision. Take the medicine exactly as prescribed by your doctor: for dosage and duration. Most recommended dose is two tablets a day.

      Q16. For how many days should I take the AF 150MG tablet?

      The number of days that any medicine must be taken varies from patient to patient; and case to case. So always stick to your doctor’s suggestion about how many days to take this medicine.

      Q17. When should I take AF 150MG tablet?

      Use the medicine exactly as prescribed by your doctor for the dosage and duration.

      Note: All of the above information is for reference purpose only. It is always recommended that you consult a medical professional.

      Seller Information
      Manufactured By

      SYSTOPIC LABORATORIES PVT LTD

      101, pragati chambers, commercial complex, ranjit nagar, new delhi-110008

      Packed By

      SYSTOPIC LABORATORIES PVT LTD

      101, pragati chambers, commercial complex, ranjit nagar, new delhi-110008

      Applicable Offers

      • 20% Discount
        On prescription medicines, orders above Rs 1000 T & C

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