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Uses and Benefits

Uses and Benefits

Alprax Z Tablet 0.25mg is used to treat anxiety disorders and anxiety associated with depression, panic disorder with agoraphobia. Besides, it is also used to treat disturbed biorhythms, and sleep disorders. However, the uses mentioned here are not exhaustive. There may be other conditions for which this medication may be used upon a doctor’s discretion.


The active ingredients of Alprax Z Tablet 0.25mg are Alprazolam 0.25mg and Melatonin 3mg.

Mechanism of Action of Drugs

Mechanism of Action of Drugs

Alprazolam belongs to a class of medications called benzodiazepines which acts on the nervous system (brain and nerves) to produce a calming effect thereby relieving pain and anxiety disorders.

Melatonin helps in managing sleep disorders.

Contraindications and Cautions

Contraindications and Caution

Patients with the following conditions are suggested to seek advice from their health care professionals before taking the Alprax Z Tablet 0.25mg:

  • Hypersensitivity to any of the ingredients used in the Alprax Z Tablet 0.25mg such as Alprazolam and Melatonin
  • Avoid abrupt withdrawal
  • Caution:
  • Pulmonary impairment
  • Sleep apnea
  • CNS depression
  • Alcohol use
  • Alcohol or drug abuse history
  • Seizure history
  • Renal impairment
  • Hepatic impairment
  • Elderly or debilitated patients
  • Depression
  • Smoking habit changes
  • Elevated gastric PH
  • Salivary flow decreased
  • PKU
Side Effects

Side and Adverse Effects

The following side effects may or may not occur during the usage of this Alprax Z Tablet 0.25mg. It is generally well tolerated when taken in the prescribed dosage guidelines. More common ones are generally mild and may include:

  • Drowsiness
  • Fatigue
  • Impaired vision
  • Irritability
  • Amnesia
  • Appetite changes
  • Confusion
  • Dizziness
  • Impaired concentration
  • Xerostomia
  • Libido changes
  • Urinary retention
  • Menstrual irregularities
  • Sialorrhea
  • Hypotension
  • Rash
  • Diplopia
  • LFT’s elevated
  • Disinhibition
  • Incontinence
  • Disturbance in normal cardiac rhythm.

Rare but more serious adverse effects may include:

  • Respiratory depression
  • Dependency, abuse
  • Seizures
  • Suicidality
  • Tachycardia
  • Hypotension
  • Syncope
  • CNS stimulation, paradoxical
  • Stevens-johnson syndrome
  • Angioedema
How to Use

How to Use

Do not exceed the dose prescribed by your doctor.
Swallow the tablet whole immediately after opening it from the strip. Do not break/chew/cut it instead.
Avoid missing/forgetting a dose. If you do, take it as soon as you remember; but if it is almost time for your next dose, skip it and take it according to your normal schedule. Don’t consume two doses at the same time which may be dangerous to your health.
Alprax Z Tablet 0.25mg should be taken either with or without food. However, to reduce side effects, take it immediately after meals – this reduce sleepiness and drowsiness.
Take the medication at the prescribed time and dosage.


Avoid taking more than the prescribed dosage. In case of an accidental overdose, promptly seek medical advice. Depending on the dosage, symptoms may vary but you may experience one or more of the following signs or symptoms:

  • CNS depression ranges from depression to coma
  • Mental confusion
  • Lethargy
  • Ataxia
  • Hypotonia
  • Hypotension
  • Respiratory depression
  • Rarely coma and death
Warnings and Precautions

Warnings and Precautions

Take Alprax Z Tablet 0.25mg only on the advice of a medical practitioner. Dosage adjustment or complete avoidance of the medication may be required in the following conditions:


Do not take Alprax Z Tablet 0.25mg if you are pregnant or planning to become pregnant. However, consider taking only if it is suggested by your doctor.


Do not take this tablet if you are a nursing mother because this drug can pass into breast milk and can harm a breastfeeding infant.


Since consuming this medicine would induce sleep/cause dizziness. Do not drive, operate heavy machinery or involve in any works which may demand your attention/physical strength.


Increased bioavailability with grapefruit juice and enhanced CNS depressant effect with alcohol.

Drug Interactions:

Caution always advised when used with other drugs. Therefore, always inform your doctor about your current list of medication(s) (if any) during the treatment.

  • Keep the medicine out of sight and reach of children.
  • Store at room temperature away from heat and moisture.
  • Do not use Alprax Z Tablet 0.25mg beyond its expiry.
FDA Pregnancy Category

FDA Pregnancy Category

Category N: No information available.

Drug Composition information
What is Alprazolam for:

It is used to treat anxiety and panic attacks.

How does Alprazolam work:

It works by decreasing abnormal excitement in the brain.

How should Alprazolam be used:

Take Alprazolam exactly as directed by your doctor. Do not take more or less than instructed by your doctor. Do not take Alprazolam for a longer period of time than instructed by your doctor. In some medical conditions, such as anxiety, panic attacks and insomnia, it is not advisable to take Alprazolam long-term. See your doctor if Alprazolam does not seem to help you. If you are taking Alprazolam as a sleeping pill, you should take it only when you have problems sleeping and when you are able to sleep for 7-8 hours without being interrupted. Take it just before you go to bed. - If you have been taking Alprazolam over a certain period of time, do not stop taking Alprazolam suddenly as this may cause withdrawal symptoms such as seizures, cramps, vomiting, sweating and tremors. Your doctor will reduce the dose of Alprazolam gradually before stopping it completely. Follow your doctors instructions carefully. - You may take Alprazolam with or without food. However, taking it immediately after food may reduce the side effects of drowsiness and sleepiness. - If you have been given the slow-release tablet (usually marked as XR or SR), swallow it whole. Do not chew, crush or break it.

Common side effects of Alprazolam :

Feeling lightheaded, sleepy, having blurred eyesight, or a change in thinking clearly; Dry mouth; Change in sex ability; Feeling tired or weak; Change in balance.

What do I do if I miss a dose

Take a missed dose as soon as you think about it. - If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. - Many times this drug is taken on an as needed basis.

What precautions should I take when taking Alprazolam :

Alert your doctor if you are pregnant or if you become pregnant while being treated with Alprazolam. Do not take Alprazolam if you are pregnant. - It is important that you do not get pregnant while being treated with Alprazolam. - Use appropriate birth control. - Alert your doctor if you are breastfeeding. Do not breastfeed while being treated with Alprazolam. - Alert your doctor if you ever had an allergic reaction to sleeping pills such as diazepam, midazolam, lorazepam and others. - Alert your doctor if you have liver disease or an eye disease known as glaucoma. - Alert your doctor if you have lung or breathing problems such as sleep apnea, myasthenia gravis or if you are at risk of falls. - Do not give Alprazolam to children, unless specifically instructed by the childs doctor. - Alprazolam is not meant for children younger than 18 years old.

When do I need to seek medical help

Seek help if you have signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Inform doctor if you experience any bruising or bleeding, any rash, or if any side effect or health problem is not better or you are feeling worse.

Can I take Alprazolam with other medicines:

Do not take Alprazolam with antifungal medications, especially itraconazole and ketoconazole. - Alert your doctor quickly if you are taking any of these medicines: - other sleeping pills. - any medicines that cause drowsiness such as opioid (morphine-like) pain-killers, antihistamines and medicines for mood and personality disorders. - antidepressants such as fluoxetine, nefazodone, fluvoxamine, sertraline, paroxetine. - antibiotics such as rifampicin, erythromycin, clarithromycin, telithromycin, doxycycline, isoniazid. - epilepsy (fits or seizure) medicines such as phenytoin, carbamazepine, phenobarbitone. - heart or blood pressure medicines such as diltiazem, nifedipine, nicardipine, verapamil, quinidine, amiodarone - AIDS (HIV) medicines. - birth control pills. - gastric medicines such as cimetidine. - asthma medicines such as theophylline. Always inform your doctor and pharmacist if you are taking any other medicines, including herbal tonics, supplements and medicines that you buy without a prescription.

Are there any food restrictions

Avoid alcohol and grapefruit juice.

How do I store Alprazolam :

Store in a cool, dry place away from the reach of children. - Medicines must not be used past the expiry date.

Pregnancy Category

Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Therapeutic Classification

Hypnotics & Sedatives, Anxiolytics

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indrad -382721,dist mehsana,india

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indrad -382721,dist mehsana,india

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