AMFIGHT 50MG INJ

What is Amphotericin B liposomal for:

Amphotericin B liposomal is used for treating fungal infections in certain patients, including patients who cannot use other forms of amphotericin B. It is used to treat cryptococcal meningitis in HIV patients and to treat certain protozoal infections (visceral leishmaniasis). It may also be used for other conditions as determined by your doctor.

How does Amphotericin B liposomal work:

Amphotericin B is an antifungal antibiotic. It works by killing the fungus and preventing its reproduction.

How should Amphotericin B liposomal be used:

Amphotericin B is usually administered as an injection at your doctor's office, hospital, or clinic. If you are using it at home, carefully follow the injection procedures taught to you by your health care provider.

Common side effects of Amphotericin B liposomal :

Check with your doctor if any of these side effects persist or become bothersome: Chills; coughing; fever; headache; loss of appetite; muscle or joint pain; nausea; rapid heartbeat; sleeplessness; stomach pain; weight loss. Seek medical attention right away if any of these side effects occur: Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); blood in the urine; chest pain; convulsions; dark, bloody stools; decreased urination; diarrhea; dizziness; easy bruising or bleeding; fast breathing; fast or irregular heartbeat; hearing loss; pain, redness, or inflammation at the injection site; swelling of the hands or feet; unusual tiredness or weakness; vomiting; yellowing of eyes or skin.

What do I do if I miss a dose

If you miss a dose of amphotericin b liposome, contact your doctor immediately.

What precautions should I take when taking Amphotericin B liposomal :

If amphotericin b liposome contains particles or is discolored, or if the vial is cracked or damaged in any way, do not use it. Do not use amphotericin b if:
you are allergic to any ingredient in amphotericin b liposome (including soy)
you are taking an azole antifungal (eg, ketoconazole)
Important safety information:
Amphotericin b liposome may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to amphotericin b liposome. Using amphotericin b liposome alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
It is important to use amphotericin b liposome for the full course of treatment. Failure to do so may decrease the effectiveness of amphotericin b liposome and may increase the risk that the fungus will no longer be sensitive to amphotericin b liposome and will not be able to be treated by this or certain other antibiotics in the future.
To reduce side effects, your doctor may prescribe other medicines before the administration of amphotericin b liposome.
LAB TESTS, including kidney function, liver function, blood counts, and serum electrolytes, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
Use amphotericin b liposome with extreme caution in CHILDREN younger than 1 month of age. Safety and effectiveness in this age group have not been confirmed.
To clear up your infection completely, continue using amphotericin b liposome for the full course of treatment even if you feel better in a few days. Do not miss any doses.
Keep this product, as well as syringes and needles, out of the reach of children. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for proper disposal.

When do I need to seek medical help

Tell your doctor if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have kidney problems.

Can I take Amphotericin B liposomal with other medicines:

Some medicines may interact with amphotericin b liposome. Tell your health care provider if you are taking any other medicines, especially any of the following:
Azole antifungals (eg, ketoconazole) because the effectiveness of amphotericin b liposome may be decreased
Aminoglycoside antibiotics (eg, gentamicin), antineoplastic medicines (eg, cisplatin), cyclosporine, or pentamidine because side effects, such as kidney problems, may occur
Leukocyte transfusions because side effects, such as lung problems, may occur
Corticosteroids (eg, prednisone) or corticotropin because side effects, such as heart problems, may occur
Digoxin, flucytosine, skeletal muscle relaxants (eg, tubocurarine), or zidovudine because side effects and toxic effects may be increased.

How do I store Amphotericin B liposomal :

Store unused vials of amphotericin b liposome at room temperature, up to 25 degrees C. After mixing, follow the storage instructions provided by your doctor or other health care provider. Store away from heat, moisture, and light. Do not store in the bathroom. Keep amphotericin b liposome out of the reach of children and away from pets.

Pregnancy Category

Pregnancy Category:
If you become pregnant while taking amphotericin b liposome, discuss with your doctor the benefits and risks of using amphotericin b liposome during pregnancy. It is unknown if amphotericin b liposome is excreted in breast milk. Do not breast-feed while taking amphotericin b liposome.

Therapeutic Classification

Antifungals