It is used to treat low mood (depression). It is used to stop or prevent migraine headaches. It is used to ease long-term pain problems including diabetic and other neuropathies. It is used to treat anxiety. It is used to treat eating problems. It is used to treat panic attacks.
Amitriptyline affects chemicals in the brain. With low mood (depression), sleep and eating habits may get better fast. Other signs may take up to 4 to 6 weeks to get better.
Take Amitriptyline exactly as directed by your doctor. Do not take more or less than instructed by your doctor. - You may take Amitriptyline with or without food. - Amitriptyline must be taken regularly for it to work well. You may see the benefits of Amitriptyline only after 2-4 weeks. Do not be discouraged if you do not feel better soon after taking the medicine. Do not stop taking Amitriptyline unless instructed by your doctor. You may feel unwell if Amitriptyline is stopped suddenly.
Feeling lightheaded, sleepy, having blurred eyesight, or a change in thinking clearly; Feeling dizzy; Hard stools (constipation); Dry mouth; Change in color of urine to blue or green
Take a missed dose as soon as you think about it. - If it is close to the time for your next dose, skip the missed dose and go back to your normal time. - Do not take 2 doses at the same time or extra doses. - Do not change the dose or stop this drug. - Talk with the doctor.
Alert your doctor if you have bipolar disorder, mania, heart disease or severe liver disease. - It is also important to let your doctor know if you are pregnant, planning to get pregnant, or breastfeeding. - Alert your doctor if you have taken other mood medicines known as monoamine oxidase inhibitors (MAOIs) in the last 14 days. - Some examples of MAOIs include phenelzine, moclobemide and tranylcypromine. - Alert your doctor if you are being treated with a gastric reflux medicine known as cisapride.
Seek help if you think there was an overdose or signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Seek help if you are planning to harm yourself or the want to harm yourself gets worse. - A fast heartbeat. - Very bad dizziness or passing out. Change in thinking clearly and with logic. - Not able to pass urine. - Feeling very tired or weak. - Very nervous and excitable. - Any rash. Side effect or health problem is not better or you are feeling worse.
Alert your doctor if you are taking any of these medicines: - monoamine oxidase inhibitors (also used to treat depression) such as moclobemide, phenelzine, and tranylcypromine. - cisapride (a gastric reflux medicine). - selegiline (a medicine for Parkinson’s disease). - linezolid (an antibiotic). - artemether and lumefantrine (malaria medicines). You will also need to inform your doctor if you are taking any of these: - other antidepressants, sedatives or anxiety medicines. - any other mood medicines. - epilepsy medicines. - blood pressure medicines such as gaunethidine, debrisoquine, betanidine and clonidine - anticholinergics, commonly used to treat runny nose, allergies, travel sickness, such as chlorpheniramine, promethazine, hydroxyzine, and dimenhydrinate. - cimetidine (a stomach medicine). - heart medicines such as quinidine and flecainide. - disulfuram (a medicine used to treat alcoholism). - painkillers such as tramadol, morphine or fentanyl Always inform your doctor and pharmacist if you are taking any other medicines, including herbal tonics, supplements and medicines that you buy without a prescription.
Store in a cool, dry place, protected from light, and away from the reach of children. - Medicines must not be used past the expiry date. - If you have been given Amitriptyline syrup, throw it away 6 months after opening.
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
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