What is Hydrochlorothiazide for:
This medication is a thiazide diuretic, prescribed for high blood pressure (hypertension) and edema.
How does Hydrochlorothiazide work:
It helps the kidneys to remove fluid from the body.
How should Hydrochlorothiazide be used:
It comes as a tablet and liquid to take by mouth, with food. dult- HTN- The recommended dose is 12.5 to 50 mg once daily.
Edema- The recommended dose is 25-100 mg once daily or in divided doses.
Common side effects of Hydrochlorothiazide :
Low potassium levels. Signs include feeling tired, weak, numbness, or tingling; muscle cramps; hard stools (constipation); throwing up; or a fast heartbeat. Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing. Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. Dry mouth. Good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. See a dentist often.
What do I do if I miss a dose
Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses.
What precautions should I take when taking Hydrochlorothiazide :
If you have an allergy to hydrochlorothiazide or any other part of this drug. Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you have a sulfa (sulfonamide) allergy, talk with your doctor. If you have kidney disease. If you are pregnant or may be pregnant.
When do I need to seek medical help
If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Signs of low potassium. Very bad dizziness or passing out. Very upset stomach or throwing up. Not able to pass urine. Sudden change in eyesight, eye pain, or irritation. Any rash. Side effect or health problem is not better or you are feeling worse.
Can I take Hydrochlorothiazide with other medicines:
Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.
Are there any food restrictions
Avoid Alcohol
How do I store Hydrochlorothiazide :
Store in a cool, dry place away from the reach of children. - Medicines must not be used past the expiry date.
Pregnancy Category
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.
Therapeutic Classification
Diuretics
What is Aliskiren for:
It is used for treating hypertension (high blood pressure)
How does Aliskiren work:
Aliskiren is a direct renin inhibitor. It works by blocking of the action of a hormone called renin in the body there by relaxing blood vessels, which in turn lowers blood pressure and helps the heart to pump blood more easily.
How should Aliskiren be used:
Take aliskiren with or without food. However, take it the same way each time. If you take aliskiren on an empty stomach, always take it on an empty stomach. If you take it with food, always take it with food. You will need to take care not to become dehydrated while you are taking aliskiren. This may increase your risk of low blood pressure. Take aliskiren on a regular schedule to get the most benefit from it. Aliskiren works best if it is taken at the same time each day.
Common side effects of Aliskiren :
Check with your doctor if any of these side effects persist or become bothersome: Back pain; cough; diarrhea, dizziness; flu-like symptoms (eg, headache, muscle or joint aches, tiredness).
Seek medical attention immediately if any of these side effects occur: Severe allergic reactions (rash; hives; itching; difficulty breathing or swallowing; tightness in the chest; swelling of the hands, eyes, mouth, face, lips, throat, or tongue; unusual hoarseness); decreased urination; irregular heartbeat; seizures; stomach pain; symptoms of liver problems (eg, yellowing of the skin or eyes; dark urine; pale stools; severe or persistent nausea, stomach pain, or loss of appetite); symptoms of low blood pressure (eg, fainting, severe dizziness, light-headedness); vomiting.
What do I do if I miss a dose
Continue to take aliskiren even if you feel well. Do not miss any doses. If you however miss a dose of aliskiren, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
What precautions should I take when taking Aliskiren :
Do not use if you are allergic to any ingredient in aliskiren, you have a history of angioedema (swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or hoarseness) caused by treatment with aliskiren or another product that contains aliskiren
you are pregnant
you have either diabetes or kidney problems and you are also taking an angiotensin-converting enzyme (ACE) inhibitor (eg, lisinopril) or an angiotensin receptor blocker (ARB) (eg, losartan)
you are taking cyclosporine or itraconazole.
When do I need to seek medical help
Some medical conditions may interact with Aliskiren. Tell your doctor if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are able to become pregnant
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
you have a history of angioedema (swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or hoarseness), especially when taking an ACE inhibitor (eg, lisinopril) or an ARB (eg, losartan)
if you have a history of gout or high blood uric acid levels, heart problems (eg, heart failure), diabetes, kidney problems (eg, renal artery stenosis), stroke, heart attack, seizures, or low blood pressure
if you are dehydrated, have low blood volume, or receive dialysis treatment
if you have high blood potassium levels or low blood sodium levels, or if you are on a low-salt (sodium) diet
if you are taking another medicine for high blood pressure or heart problems.
Can I take Aliskiren with other medicines:
Tell your health care provider if you are taking any other medicines, especially any of the following:
Diuretics (eg, furosemide, hydrochlorothiazide) because the risk of low blood pressure may be increased
Atorvastatin, azole antifungals (eg, itraconazole, ketoconazole), or cyclosporine because they may increase the risk of aliskiren's side effects, including low blood pressure
Potassium-sparing diuretics (eg, spironolactone) or potassium supplements because the risk of high blood potassium levels may be increased
Nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen, indomethacin, celecoxib) because they may decrease aliskiren's effectiveness and the risk of kidney problems and high blood potassium levels may be increased
ACE inhibitors (eg, lisinopril) or ARBs (eg, losartan) because the risk of certain side effects (eg, kidney problems, high blood potassium levels, low blood pressure) may be increased.
How do I store Aliskiren :
Store aliskiren at room temperature, between 15 and 30 degrees C. Store in the original packing, away from heat, moisture, and light. Do not store in the bathroom. Keep aliskiren out of the reach of children and away from pets.
Pregnancy Category
Pregnancy category D: Aliskiren may cause birth defects or fetal death if you take it while you are pregnant. If you think you may be pregnant, contact your doctor right away. It is not known if this medicine is found in breast milk. Do not breast-feed while taking aliskiren.
Therapeutic Classification
ACE InhibitorsDirect Renin Inhibitors
