This medication is a tricyclic antidepressant (TCA), prescribed for obsessive-compulsive disorder. It increases the amount of serotonin that needs to maintain mental balance.
Clomipramine raises chemicals in the brain. With low mood (depression), sleep and eating habits may get better fast. Other signs may take up to 4 to 6 weeks to get better.
Adult- Oral- The recommended dose range is 25 to 150mgday. It comes as a tablet and capsule to take by mouth, with food.
Feeling lightheaded, sleepy, having blurred eyesight, or a change in thinking clearly. Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how this drug affects you. Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing. Hard stools (constipation). Drinking more liquids, working out, or adding fiber to your diet may help. Talk with your doctor about a stool softener or laxative. Dry mouth. Good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. See a dentist often.
Take a missed dose as soon as you think about it. - If it is close to the time for your next dose, skip the missed dose and go back to your normal time. - Do not take 2 doses at the same time or extra doses. - Do not change the dose or stop this drug. - Talk with the doctor.
Alert your doctor if you have any kind of heart disease or a recent heart attack. Alert your doctor if you have bipolar disorder, mania, glaucoma (high pressure in the eye) or difficulty passing urine. It is also important to inform your doctor if you are pregnant or if you become pregnant while being treated with Clomipramine. Do not breastfeed while being treated with Clomipramine. Do not take Clomipramine if you are taking or have taken other mood medicines known as monoamine oxidase inhibitors (MAOIs) in the last 14 days. Some examples of MAOIs include isocarboxazid, phenelzine, moclobemide, selegiline and tranylcypromine. Alert your doctor immediately if you are taking or have taken any of these medicines or other MAOIs.
If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. If you are planning to harm yourself or the want to harm yourself gets worse. Very bad dizziness or passing out. Change in thinking clearly and with logic. Very nervous and excitable. Not able to pass urine. Feeling very tired or weak. Any rash. Side effect or health problem is not better or you are feeling worse.
Do not take Clomipramine if you are taking or have taken other mood medicines known as monoamine oxidase inhibitors (MAOIs) in the last 14 days. Some examples of MAOIs include isocarboxazid, phenelzine, moclobemide, selegiline and tranylcypromine. Alert your doctor immediately if you are taking or have taken any of these medicines or other MAOIs. Alert your doctor if you are taking any of these medicines: - any other antidepressants. - blood pressure medicines such as clonidine, guanethidine, debrisoquine and bethanidine. - selegiline (a medicine used to treat Parkinson’s disease). You will also need to inform your doctor if you are taking any of these: - any other medicines used to treat depression and other mood disorders, especially lithium, fluoxetine or alprazolam. - epilepsy (fits) medicines. - hay fever, allergy or travel sickness medicines. - cimetidine (a gastric medicine). - heart medicines such as digoxin, propafenone, flecainide, and quinidine. - disulfiram (a medicine used to treat alcohol addiction). - blood-thinners such as warfarin. - methylphenidate (a medicine used to treat attention deficit hyperactive disorder). - birth control pills. Always inform your doctor and pharmacist if you are taking any other medicines, including herbal tonics, supplements and medicines that you buy without a prescription.
Store it at room temperature and away from moisture.
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
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