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      CLOZOTIC 5ML EAR DROPS Out of Stock Get Notified

       Clozotic 5ml ear drops
      Uses and Benefits

      Uses and Benefits

      Clozotic 5ML ear drops is a combination medicine used to treat ear infections caused by microorganisms such as bacteria and fungus characterised by symptoms such as redness and swelling of the external and middle part of the ear, hearing loss, fluid mixed with pus discharge, etc. It works by inhibiting and killing the growth of bacteria and fungus, thus relieving itching, discomfort, irritation and pain in the ear. However, the uses of this ear drops mentioned here are not exhaustive, there may be other conditions for which the medication may be used upon your doctor’s discretion.

      Composition

      Composition

      The active ingredients of Clozotic 5ML ear drops are Beclometasone (0.025% W/V), Chloramphenicol (5% W/V), Clotrimazole (1% W/V) and Lidocaine (1.73% W/V)

      Mechanism of Action of Drugs

      Mechanism of Action of Drugs

      Mechanism of Action of Drugs:
      Clozotic ear drops is a combination of four medicines, used to treat bacterial and fungal infections in ear. Beclometasone is a steroid which works by blocking the production of prostaglandins (chemical messengers) that cause pain and make ear red, swollen and itchy. Chloramphenicol is an antibiotic that involves in inhibition of bacterial protein synthesis by binding to 30S ribosomes, eventually killing the bacteria by damaging DNA.
      Clotrimazole is an anti-fungal drug that changes the permeability of the cell wall of the fungal cells and prevents their growth. It binds to the phospholipids of the membrane and inhibits the fungal CYP450 activity, thereby decreasing ergosterol biosynthesis that are essential for the development of the cell membrane. This results in the death of cells due to the loss of intracellular sections. Lidocaine is a local anaesthetic that decreases pain sensation by blocking pain signals from the nerves to the brain.

      Contraindications and Cautions

      Contraindications and Caution

      Patients with following conditions are suggested to seek advice from their healthcare professionals before using Clozotic ear drops.

      • Hypersensitivity to any of the ingredients used in the ear drops
      •  Epilepsy
      • Caution: Caution is advised among patients with following conditions:
      •  Psychiatric disorders
      •  Systemic infection (flu, fever, blood pressure)
      •  Severe renal and hepatic impairment
      •  Pregnancy and lactation
      Side and Adverse Effects

      The following side effects may or may not occur during the usage of Clozotic ear drops. It is usually well tolerated when used in the prescribed dosage guidelines. Most side effects are temporary and usually subsides on their own. However, consult your doctor if they persist for a longer duration. More common side effects include:

      • Itching at the application site
      • Mild irritation inside the ear
      •  Burning or stinging sensation
      • Redness
      How to Use

      How to Use

      Use Clozotic ear drops as instructed by your doctor. Do not use this ear drops for durations shorter or longer than suggested by your doctor. Continue to use this drug until completion of the maximum amount prescribed even though the symptoms disappear after medicine has begun. Stopping the medication too early can allow the growth of the fungus to begin, which can lead to an infection relapse.
      Follow all the instructions mentioned on the label before usage. Wash your hands thoroughly before and after instilling Clozotic ear drops. Tilt your head towards one side and place ear drops in the ear canal and keep head tilted for 2-3 minutes to let the drops soak in the ear. Repeat for the other ear if required after 5 minutes. Use the exact number of drops recommended by your doctor.

      Overdosage

      void using Clozotic ear drops more than required. If you notice any unusual or abnormal reactions after taking the medicine, promptly seek medical attention. Consult your doctor if you experience any allergic reaction. Symptoms of over dose may include:

      • Burning sensation
      •  Severe itching
      • Eczema
      Warnings and Precautions

      Use Clozotic ear drops on the advice of your medical practitioner. Complete avoidance of the ear drops may be required in the following conditions:

      Kidney:

      Since there is not enough reliable information about the safety of using this ear drops for renal patients, consult your doctor if you have renal problems and stay on the safe side.

      Liver:

      Since there is not enough reliable information about the safety of using this ear drops for hepatic patients, consult your doctor if you have liver problems and stay on the safe side.

      Pregnancy:

      Clozotic ear drops is not considered safe to use in pregnant women unless the potential benefits outweigh the risks involved. Animal studies have shown no or low adverse effects on fetus; however, there are limited human studies. It is recommended that you consult your doctor before using this ear drops.

      Lactation:

      This medicine is not considered safe to use in nursing mothers unless the potential benefits outweigh the risks involved. Since the effect of the medicine on infants is not clearly established, we recommend that you to consult your doctor before using the ear drops.

      Alcohol:

      Since there is not enough reliable information about the interaction of Clozotic ear drops with alcohol, consult your doctor and stay on the safe side.

      Driving:

      Clozotic ear drops do not cause drowsiness or dizziness. Since there is not enough reliable information about the safety of using this ear drops, consult your doctor and stay on the safe side.

      Food:

      There are no known food interactions with Clozotic ear drops.

      Drug Interactions:

      There are no known drug interactions with Clozotic ear drops. Check with your medical professional about all the possible interactions of other topical corticosteroids or drugs you’re taking.

      Precautions
      • Do not use the open bottle for more than one month
      • Do not touch the tip of the dropper to avoid contamination
      •  Do not use this medication for durations shorter or longer than suggested by your doctor
      •  Store at room temperature (20-30 degree Celsius)
      FDA Pregnancy Category

      FDA Pregnancy Category

      Category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


      Drug Composition information
      What is Chloramphenicol for:

      This medication is an antibiotic, prescribed for certain types of bacterial infection. It kills or slows the growth of sensitive bacteria.

      How does Chloramphenicol work:

      Chloramphenicol works to harm the bacteria and fight the infection.

      How should Chloramphenicol be used:

      Adult: PO- The recommended dose is 50 mgkgday in 4 divided doses, may increase to 100 mgkgday in more severe infections. Eye Drops: As 0.5% solution: Instill 1 or 2 drops 2 hourly. It comes as a tablet to take by mouth, on an empty stomach. It also comes as eye drops to instill into the affected eyes as directed by your physician.

      Common side effects of Chloramphenicol :

      Bad taste in your mouth. This most often goes back to normal. Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. Loose stools (diarrhea). Yogurt or probiotics may help. You may get these products at health food stores or in some pharmacies. Anemia, low white blood cell count, and low platelet count may rarely happen. Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing. For women, vaginal yeast infection. Report itching or discharge. A small number of people may have low blood pressure or more acid in the blood.

      What do I do if I miss a dose

      Call your doctor to find out what to do.

      What precautions should I take when taking Chloramphenicol :

      If you have an allergy to chloramphenicol or any other part of this drug. - Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. - If you have any of these health problems: Bone marrow disease, liver disease, low blood cell count, or poor kidney function. - If you have G6PD deficiency.

      When do I need to seek medical help

      If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Very bad dizziness or passing out. Very upset stomach or throwing up. Feeling very tired or weak. Very loose stools (diarrhea), even after drug is stopped. Any bruising or bleeding. Any rash. Side effect or health problem is not better or you are feeling worse.

      Can I take Chloramphenicol with other medicines:

      Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.

      Are there any food restrictions

      Avoid Alcohol

      How do I store Chloramphenicol :

      Store it at controlled room temperature (15-30oC).

      Pregnancy Category

      Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

      Therapeutic Classification

      Chloramphenicols, Eye Anti-Infectives & Antiseptics, Ear Anti-Infectives & Antiseptics


      Frequently Asked Questions

      Frequently Asked Questions
      Q1. What is the use of Clozotic 5ML Ear drops?

      Clozotic 5ML ear drops is combination medicine used to treat ear infections caused by microorganisms such as bacteria and fungus characterised by symptoms such as redness and swelling of the external and middle part of the ear, hearing loss, fluid mixed with pus discharge, etc. It works by inhibiting and killing the growth of bacteria and fungus, thus relieving itching, discomfort, irritation and pain in the ear.

      Q2. Can we use this ear drops daily?

      Use this medicine exactly as directed on the label, or as prescribed by your doctor. Do not use this medicine in larger or smaller amounts or for longer than recommended.

      Q3. How many times this medicine can be used in a day?

      Use the medicine exactly as prescribed by your doctor for the dosage and duration. The usual dose is 2-4 drops. However, depending on the underlying condition, it may differ from person to person.

      Q4. What are the side effects of this ear drops?

      The ear drops are well tolerated when used in prescribed dosage guidelines. Most common side effects include itching at the application site, mild irritation inside the ear, burning or stinging sensation, redness. Most side effects are temporary and usually subsides on their own. However, consult your doctor if they persist for a longer duration.

      Q5. Does this medication make you sleepy?

      Clozotic ear drops do not cause drowsiness or dizziness. Since there is not enough reliable information about the safety of using this ear drops, consult your doctor and stay on the safe side.

      Q.6. When should I use this medicine?

      Use the ear drops exactly as prescribed by your doctor for the dosage and duration.

      Q7. Is this medicine harmful for health?

      Clozotic ear drops is usually well tolerated when used in the recommended dosage guidelines. Over dose of the medicine may lead to burning sensation, severe itching.

      Q8. Can we use this on empty stomach or should take it with food?

      Usage of the ear drops does not depend on food.

      Q9. What are the precautions I need to follow while using Clozotic ear drops?

      If you ever had impaired kidney function, liver impairment or heart disease, let your doctor know before using this medicine. Inform your doctor about all the medicines you take to ensure that you are healthy. Caution is advised among patients who have an allergy to any components used in the ear drops, epilepsy, psychiatric disorders, systemic infection (flu, fever, blood pressure), severe renal and hepatic impairment, pregnancy and lactation.

      Q10. Can we give this medicine to a child?

      If used according to the directions given by your doctor, it is safe to be used by children.

      Q11. How long does the effect of medicine last?

      The duration required for the medicine to show its effect in the body depends on the intended use and the clinical condition of the patient.

      Q12. Can I use this ear drops during pregnancy?

      Clozotic ear drops are not considered safe to use in pregnant women unless the potential benefits outweigh the risks involved. Animal studies have shown no or low adverse effects on fetus; however, there are limited human studies. It is recommended that you consult your doctor before using this ear drops.

      Q13. At what time can I use the ear drops?

      To get the most benefits, use the medicine 2-3 times a day and you should not quit unless your doctor suggests.

      Q14. Can I use this ear drops without a doctor’s prescription?

      No, do not use the medicine without doctor’s prescription.

      Q15. Is it okay to drink alcohol while I am using this medicine?

      Since there is not enough reliable information about the interaction of Clozotic ear drops with alcohol, consult your doctor and stay on the safe side.

      Q16. How to store the medicine?

      Store the medicine at room temperature (15-30 degree Celsius) in a cool and dry place. Keep the ear drops according to the instructions mentioned on the pack or label. Store the medicine in the container or the pack it came in, tightly closed.

      Q17. How is the best way to use ear drops?

      Clozotic ear drops must be used for external purpose only. Applying this ear drops to open cavities may result in severe irritation and redness.

      Q18. For how long should I apply the medicine?

      Continue to use the medicine until completion of the maximum amount prescribed by your physician, even though the symptoms disappear after medicine has begun.

      Q19. By when should I start seeing results of the medicine?

      The amount of time required for this medicine to show its action is not clinically determined. You will start to feel better in 1-2 days after using the ear drops. But continue to use the ear drops until completion of the maximum amount prescribed by your physician, even though the symptoms disappear after medicine has begun.

      Q20. What are the alternate medicines to Clozotic 5ML ear drops?

      CANDIBIOTIC EAR 5ML DROPS, EARGESIC 10ML EAR DROPS

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