Alpha-lipoic acid is a vitamin-like chemical called an antioxidant. Alpha-lipoic acid is used for diabetes and nerve-related symptoms of diabetes including burning, pain, and numbness in the legs and arms. Alpha-lipoic acid is also used for memory loss, chronic fatigue syndrome (CFS), HIV/AIDS, cancer, liver disease, diseases of the heart and blood vessels (including a disorder called cardiac autonomic neuropathy) and Lyme disease.It is also used to treat eye-related disorders, such as damage to the retina, cataracts, glaucoma, and an eye disease called Wilson’s disease.
Alpha-lipoic acid seems to help prevent certain kinds of cell damage in the body, and also restores vitamin levels such as vitamin E and vitamin C. There is also evidence that alpha-lipoic acid can improve the function and conduction of neurons in diabetes.Alpha-lipoic acid is used in the body to break down carbohydrates and to make energy for the other organs in the body.Alpha-lipoic acid seems to work as an antioxidant, which means that it might provide protection to the brain under conditions of damage or injury. The antioxidant effects might also be helpful in certain liver diseases.
For treating type 2 diabetes and improving symptoms such as burning, pain, and numbness in the legs and arms. Use the medicine daily as directed by the physician
Alpha-lipoic acid is possibly safe for most adults when taken by mouth , when used intravenously or when applied to the skin. People taking alpha-lipoic acid by mouth might get a rash. People at risk for thiamine deficiency should take a thiamine supplement.People with diabetes should be careful to check their blood sugar levels because alpha-lipoic acid might lower blood sugar.
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Although not all side effects are known, alpha-lipoic acid is thought to be possibly safe when taken as directed.
Stop taking alpha-lipoic acid and call your doctor at once if you have:
Low blood sugar-headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery; or a light-headed feeling, like you might pass out.
Common side effects may include:nausea; or skin rash.
Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra alpha-lipoic acid to make up the missed dose.
Alpha-lipoic acid can decrease blood sugar levels. Your diabetes medications might need to be adjusted by your healthcare provider.Alcohol can lower the amount of thiamine (vitamin B1) in the body. Taking alpha-lipoic acid when there is a shortage of thiamine might cause serious health problems. If you drink a lot of alcohol and take alpha-lipoic acid too, you should take a thiamine supplement.Taking alpha-lipoic acid might interfere with treatments for under-active or over-active thyroid.
Avoid using alpha-lipoic acid together with other herbal/health supplements that can also lower your blood sugar. This includes devil's claw, fenugreek, garlic, guar gum, horse chestnut, Panax ginseng, psyllium, and Siberian ginseng.
Consult your doctor if you have:
liver disease;
diabetes (alpha-lipoic acid can cause low blood sugar);
a thyroid disorder;
a thiamine deficiency (thiamine is a form of vitamin B); or
if you drink large amounts of alcohol.
Medications for cancer (Chemotherapy) interacts with Alpha-Lipoic acid. Alpha-lipoic acid is an antioxidant. There is some concern that antioxidants might decrease the effectiveness of some medications used for cancers.
Medications for diabetes (Antidiabetes drugs) interacts with Alpha-Lipoic acid. Alpha-lipoic acid might decrease blood sugar. Diabetes medications are also used to lower blood sugar. Taking alpha-lipoic acid along with diabetes medications might cause your blood sugar to go too low.
Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.
Do not take alpha-lipoic acid without medical advice if you are using any of the following medications: Insulin or oral diabetes medicine; Medicines to treat underactive thyroid, such as levothyroxine (Synthroid) and others; or Cancer medicines (chemotherapy).
Store at room temperature away from moisture and heat.
Pregnancy Category:N. Not enough is known about the use of alpha-lipoic acid during pregnancy and breast-feeding. Stay on the safe side and avoid use.
Supplements & Adjuvant Therapy
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