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Country of origin: INDIA

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Cremaffin Plus Syrup 225ml
Uses and Benefits

Uses and Benefits

Cremaffin Plus Syrup 225ml is used as a laxative which promotes the movement of intestine and evacuation of fecal matter or bowel movement without exerting pressure to eliminate the feces and used also as a purgative which forms watery stools to relieve from constipation and rectal pain while expelling the fecal matter. This medicine also helps to neutralize the acid in the stomach. However, the uses mentioned here are not exhaustive. There may be other conditions for which this medication may be used upon doctor’s discretion.



The active ingredients of Cremaffin Plus Syrup 225ml are Liquid Paraffin 1.25ml, Magnesium Hydroxide 3.75ml, and Sodium Picosulphate 3.33mg/5ml.

Mechanism of Action of Drugs

Mechanism of Action of Drugs

Magnesium Hydrochloride neutralizes hyperacidity in the stomach and also works as a laxative when taken in high doses.

Sodium Picosulphate triggers the walls of the large intestine and rectum by this the muscles contract and moves the matter of the intestine through the rectum and the colon eliminates all the feces in the intestine. This is how it relieves from constipation.

Contraindications and Cautions

Contraindications and Caution

Patients with the following conditions are suggested to seek advice from their health care professionals before using the Cremaffin Plus Syrup 225ml:

  • Hypersensitivity to any of the ingredients used in the Cremaffin Plus syrup such as Liquid Paraffin, Magnesium Hydroxide, and Sodium
  • Picosulphate
  • Renal failure
  • Colostomy or ileostomy
  • Intestinal perforation
  • GI Obstruction
  • Toxic colitis
  • Toxic megacolon or ileus
  • Gastric retention
  • Caution:
  • GI Obstruction
  • GI Bleeding
  • Renal impairment
  • Severe ulcerative colitis
  • Arrhythmia risk
  • Renal impairment
  • Concurrent Nephrotoxic agent use
  • Seizure risk
  • Aspiration risk
  • Impaired gag reflex
  • History or concurrent antibiotic use
Side Effects

Side and Adverse Effects

The following side effects may or may not occur during the usage of Cremaffin Plus Syrup 225ml. It is generally well tolerated when taken in the prescribed dosage guidelines. More common ones are generally mild and may include:

  • Diarrhea
  • Abdominal pain
  • Dehydration
  • Nausea
  • Vomiting
  • Granulomatous reaction
  • Headache
  • Hyponatremia
  • Hypokalemia
  • Hypermagnesemia
  • Hypocalcemia
  • Hypochloremia

Rare but more serious adverse effects may include:

  • Hypermagnesemia
  • Electrolyte imbalance (Severe)
  • Renal impairment
  • Seizures
  • Arrhythmia
  • Ischemic colitis
  • Colonic Mucosal aphthous ulcer
How to Use

How to Use

Do not exceed the dose prescribed by the doctor.
Cremaffin Plus Syrup 225ml is meant for oral administration. Shake the bottle well before using.
Dosage can be administered with the cap that comes along with the container.
Avoid missing or forgetting a dose. If you do, take it as soon as you remember; but if it is time for your next dose, skip it and take it according to your normal schedule. Don’t consume two doses at the same time which is dangerous to your health.
Dosage as suggested by your doctor or follow the instructions given on the prescription.
Usually taken at bedtime or in the morning before breakfast; Dosage as suggested by your doctor or follow the directions given on the prescription.


Avoid taking more than the prescribed dosage. In case of an accidental overdose, look for any new symptoms. If you observe any, promptly seek medical advice or report it to the nearby poison control center.

Warnings and Precautions

Warnings and Precautions

Take only on the advice of a medical practitioner. Dosage adjustment or complete avoidance of the medication may be required in the following conditions:


Do not take this syrup if you have any renal problems. Talk to your doctor before the consumption of the Cremaffin Plus syrup 225ml.


Check with your doctor once if you have any hepatic problems before taking the syrup.


Do not take this medicine without your doctor’s advice if you are pregnant or planning to become pregnant.


Check with your doctor once if you are a nursing mother before taking the syrup because it is not known whether this medicine may pass into breast milk or not or are it could harm an infant.

Drug Interactions:

Caution always advised when used with other medicines, your current list of medication which you start or stop or your previous list of medication.

  • Keep the medicine out of sight and reach of childreen.
  • Store at room temperature away from heat and moisture.
  • Do not use the Cremaffin Plus syrup beyond its expiry.
FDA Pregnancy Category

FDA Pregnancy Category

Category N: No information available.

Seller Information
Manufactured By


abbott india ltd,3-4 corporarte park,sion-trombay road,mumbai-400071

Packed By


abbott india ltd,3-4 corporarte park,sion-trombay road,mumbai-400071

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