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Country of origin: INDIA

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30 Units/pack

MRP 208.35

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FLAT 20% OFF On bills above 1000.0
DOXINATE TAB

Doxinate tablet
Uses and Benefits

Uses and Benefits

Doxinate tablet belongs to group of medicines called anti-emetics. It is used to treat and prevent symptoms such as nausea, vomiting, headaches associated with pregnancy. It prevents the feeling of nausea and morning sickness in pregnant women. The medicine also provides nutrition to the body. However, the uses mentioned here are not exhaustive. There may be other conditions for which the medication may be used upon your doctor’s discretion.

Composition

Composition

The active ingredients of Doxinate tablet are Doxylamine succinate 10MG and Pyridoxine 10MG

Mechanism of Action of Drugs

Mechanism of Action of Drugs

Doxylamine succinate is a histamine H-1 receptor antagonist that works by blocking the natural substance (histamine) in the body, thereby preventing nausea and vomiting. It acts on the vomiting centre in the brain to prevent vomiting sensation. Pyridoxine works by restoring the levels of vitamin B6 in the body and treats nausea and vomiting during pregnancy. It also helps in the release of glycogen stored in the liver and muscles.

Contraindications and Cautions

Contraindications and Caution

Patients with following conditions are suggested to seek advice from their healthcare professionals before using Doxinate tablet:

  • Hypersensitivity to any of the ingredients used in the tablet
  • Severe liver disease
  • Alcohol dependence
  • Premature infants or full-term neonates
  • Caution:
  • Angle closure glaucoma
  • Urinary retention
  • Prostatic hypertrophy
  • Pyloroduodenal obstruction
  • Epilepsy
  • Hepatic impairment
  • Elderly and lactation
Side Effects

Side and Adverse Effects

The following side effects may or may not occur during the usage of Doxinate tablet. It is usually well tolerated when taken in the recommended dosage guidelines. Most of the side effects are generally mild and you may experience one or more of the following symptoms:

  • Drowsiness
  • Unusual weakness and tiredness
  • Muscle stiffness and trembling
  • Irregular heartbeat
  • Headache
  • Dry mouth
  • Dizziness
  • Constipation
  • Sweating

Rare but more serious adverse effects may include:

  • Blood disorders
  • Convulsions
  • Hair loss
  • Hypotension
  • Urinary retention
How to Use

How to Use

Take Doxinate tablet as instructed by your doctor. Swallow the tablet whole with water, immediately after opening it from the strip. Do not break or crush or chew the tablet.
Avoid missing or forgetting the dose. If you do, take it as soon as you remember; but if it’s almost time for your next dose, skip it and take it according to your normal schedule. Don’t swallow two doses at the same time which is dangerous to your health.
The tablet should be taken on an empty stomach. Take the tablet at the same time as it helps to maintain a consistent level of medicine in the body. The tablet is usually taken twice a day.
Do not change the dose or stop taking the medicine before completion of the course or without consulting your doctor. Continue to use this drug until completion of the maximum amount suggested.

Overdosage

Avoid taking medicine more than the prescribed dosage. If you notice any unusual or abnormal reactions after taking the tablet, promptly seek medical attention. Depending on the dosage of Doxinate tablet, symptoms vary in individuals, you may experience one or more of the following symptoms:

  • Consciousness alterations ranging from somnolence to stupor and coma
  • Myalgia
  • Loss of coordination
  • Extrapyramidal symptoms
  • Seizures (young children)
Warnings and Precautions

Warnings and Precautions

Use this tablet only on the advice of medical practitioner. Dose adjustments or complete avoidance of the Doxinate tablet may be required in the following conditions:

Kidney:

The tablet is safe to use in patients with kidney problems. Adjustments of dose of the medicine may not be needed. If you have any renal problems, it is highly recommended that you consult doctor before the consumption of this medicine.

Liver:

Caution is advised among people with liver problems. Dose adjustments of the tablet may be needed. If you have any hepatic problems, it is highly recommended that you consult doctor before the consumption of this medicine.

Pregnancy:

Doxinate tablet is considered safe to use during pregnancy as there is no risk of fetal harm. However, consult your doctor if you are pregnant and stay on the safe side.

Lactation:

The medicine is likely safe to use during breastfeeding. Limited human data suggests that the medication may pass through the breastmilk and does not represent any significant risk to the baby. Prolonged use of the tablet may cause sleepiness and other effects in the baby.

Alcohol:

Consumption of alcohol with Doxinate tablet is not recommended as it increases side effects and causes extreme drowsiness, dizziness, light headedness. Any symptoms of abnormal reactions after taking the tablet should be reported to your doctor immediately.

Driving:

The medicine may decrease alertness, cause impaired judgement, affect your vision and make you feel dizzy, light headedness, so do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

Food:

There are no known food interactions with this tablet.

Drug Interactions:

All medicines interact differently for person to person. Inform your doctor or pharmacist if you are taking any other medicines which includes over-the-counter drugs, herbal tonics, supplements and medicines that you buy without a prescription. Alert your doctor if you are taking Doxinate tablet with phenytoin, levodopa, phenobarbitone, amitriptyline, diazepam, chlorpromazine, fluoxetine, aminoglycosides, monoamine oxidase inhibitors.

Precautions
  • Do not use this tablet post the expiry date
  • Do not use this medication for durations longer than suggested by your doctor
  • Store at room temperature (20-30 degree Celsius)
FDA Pregnancy Category

FDA Pregnancy Category

Category A: Adequate and well-controlled human studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters)


Drug Composition information
What is Doxylamine Succinate for:

This medication is a sedating antihistamine, prescribed for short-term treatment of insomnia (difficulty falling asleep or staying asleep). It is also used in combination with decongestants and other medications to relieve sneezing, runny nose, and nasal congestion caused by the common cold. It is used for morning sickness of pregnancy along with vitamin B6 in some countries.

How does Doxylamine Succinate work:

Doxylamine calms the brain.

How should Doxylamine Succinate be used:

Adult: PO- 10-20 mg at bedtime. Child: PO 5mg at bedtime. It comes as a tablet to take by mouth for sleep with or without food, and in combination with other medications as a liquid and liquid-filled capsule to treat symptoms of the common cold.

Common side effects of Doxylamine Succinate :

Feeling lightheaded, sleepy, having blurred eyesight, or a change in thinking clearly. Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how this drug affects you. Hard stools (constipation). Drinking more liquids, working out, or adding fiber to your diet may help. Talk with your doctor about a stool softener or laxative. Dry mouth. Good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. See a dentist often.

What do I do if I miss a dose

Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.

What precautions should I take when taking Doxylamine Succinate :

If you have an allergy to doxylamine or any other part of this drug. - Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.

When do I need to seek medical help

If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Not able to pass urine. Feeling very tired or weak. Any rash. Side effect or health problem is not better or you are feeling worse.

Can I take Doxylamine Succinate with other medicines:

Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.

Are there any food restrictions

Avoid Alcohol

How do I store Doxylamine Succinate :

Keep it in an airtight container, and out of reach of children. Store it at room temperature and away from excess heat and moisture.

Pregnancy Category

Category A : Adequate and well-controlled human studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).

Therapeutic Classification

Antihistamines & Antiallergics


Frequently Asked Questions

Frequently Asked Questions
Q1. What is the use of the Doxinate tablet?

The tablet belongs to group of medicines called anti-emetics. It is used to treat and prevent symptoms such as nausea, vomiting, headaches associated with pregnancy. It prevents the feeling of nausea and morning sickness in pregnant women. The medicine also provides nutrition to the body.

Q2. What are the side effects of the Doxinate tablet?

The tablet is well tolerated when taken in prescribed dosage guidelines. Most common side effects include drowsiness, stomach discomfort, sweating, unusual weakness and tiredness, muscle stiffness and trembling, irregular heartbeat, headache, dry mouth, dizziness, constipation. Its use may also lead to uncommon side effects such as urinary retention, blood disorders, convulsions, hair loss, hypotension.

Q3. Should we take Doxinate tablet with food or without food?

The tablet should be taken on an empty stomach.

Q4. What are the precautions to be followed while taking the Doxinate tablet?

If you ever had impaired kidney function, sever liver impairment or heart disease, let your doctor know before taking this medicine. Inform your doctor about all the medicines you take to ensure that you are healthy. This medicine is contraindicated in patients with hypersensitivity to any of the ingredients used in the tablet, severe liver disease, alcohol dependence, premature infants or full-term neonates. Caution is advised among patients with angle closure glaucoma, urinary retention, prostatic hypertrophy, pyloroduodenal obstruction, epilepsy, hepatic impairment, elderly and lactation.

Q5. Does Doxinate tablet make you sleepy?

The tablet may decrease alertness, cause impaired judgement, affect your vision and make you feel dizzy, difficulty in concentration, fatigue, light headedness, so do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

Q6. Is Doxinate tablet harmful? What does an overdose of Doxinate tablet lead to?

The tablet is usually well tolerated when taken in the recommended dosage guidelines. Over dose of the medicine may lead to consciousness alterations ranging from somnolence to stupor and coma, myalgia, loss of coordination, extrapyramidal symptoms, seizures (young children).

Q7. Can I take Doxinate tablet during pregnancy?

The tablet is considered safe to use during pregnancy as there is no risk of fetal harm. However, consult your doctor if you are pregnant and stay on the safe side.

Q8. Can Doxinate tablet be taken without a doctor’s prescription?

No, do not take the medicine without doctor’s prescription.

Q9. Is it okay to drink alcohol while I am on the Doxinate tablet?

Consumption of alcohol with this medicine is not recommended as it increases side effects such as difficulty in breathing, dizziness, light headedness. Any symptoms of abnormal reactions after taking the tablet should be reported to your doctor immediately.

Q10. How to store Doxinate tablet?

Store the medicine at room temperature (25-30 degree Celsius) in a cool and dry place. Keep the tablet according to the instructions mentioned on the pack or label. Store the medicine in the container or the pack it came in, tightly closed.

Q11. If I have trouble swallowing Doxinate tablet, can I mix it in water and drink it?

This tablet is designed to be swallowed with water. If you take them in a way they weren’t intended to be used, you could experience an overdose if the active constituent enters the blood stream too quickly. Alternatively, if it enters your body too slowly, it may never achieve a high enough concentration to be completely functional.

Q12. Can we give Doxinate tablet to children?

This tablet is not recommended for children since the safety and efficacy of use are not clinically established.

Q13. By when should I start seeing the results of the Doxinate tablet?

The amount of time required for this medicine to show its action in the body is clinically not established.

Q14. How long does the effect of Doxinate tablet last?

The duration for which this medicine remains active in the body is clinically not established.

Q15. Can we take Doxinate tablet daily? If yes, how many tablets can we take everyday?

Medicines should always be taken under medical supervision. Take the medicine exactly as prescribed by your doctor: for dosage and duration. Most recommended dose is two tablets per day.

Q16. For how many days should I take the Doxinate tablet?

The number of days that any medicine must be taken varies from patient to patient; and case to case. So always stick to your doctor’s suggestion about how many days to take this medicine.

Q17. When should I take Doxinate tablet?

Use the medicine exactly as prescribed by your doctor for the dosage and duration.

Note: All of the above information is for reference purpose only. It is always recommended that you consult a medical professional.

Seller Information
Manufactured By

SVIZERA HEALTHCARE

(a div of maneesh pharmaceuticals ltd)29-33 anoitary industrial piots gowandi,mumbai 400043

Packed By

SVIZERA HEALTHCARE

(a div of maneesh pharmaceuticals ltd)29-33 anoitary industrial piots gowandi,mumbai 400043

Applicable Offers

  • 20% Discount
    On prescription medicines, orders above Rs 1000 T & C
  • 10% Discount
    On prescription medicines, orders above Rs 200 T & C

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