This medication is a proton pump inhibitor (PPI), prescribed for gastroesophageal reflux disease (GERD). With amoxicillin and clarithromycin it is used for treatment of Helicobacter pylori infection and duodenal ulcer. It is also used to aid in reduction in occurrence of gastric ulcers associated with continuous NSAID therapy, and in Zollinger-Ellison syndrome. It blocks the production of stomach acid.
Esomeprazole helps avoid harm to the GI (gastrointestinal) tract caused by stomach acid or infection.
GERD: 20 or 40 mg is given once daily for 4-8 weeks. In children ages 1-11, the dose is 10 or 20 mg daily. H. pylori: 40 mg is administered once daily in combination with amoxicillin and clarithromycin for 10 days. NSAID-induced ulcers: 20 to 40 mg daily for 6 months. Zollinger-Ellison syndrome is treated with 40 mg twice daily. It comes as a tablet or capsule to take by mouth, once a day, one hour before meal.
Headache. Loose stools (diarrhea). Hip, spine, or wrist fractures may rarely happen.
Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.
If you have an allergy to esomeprazole or any other part of this drug. Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Very bad dizziness or passing out. A fast heartbeat. Very loose stools (diarrhea). Very bad belly pain. Very bad bone pain. Very bad muscle pain or weakness. Any bruising or bleeding. Seizures. Any rash. Side effect or health problem is not better or you are feeling worse.
Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.
Injection: Powder for injection: Store at (20 - 25°C). Protect from light. Reconstituted solution for injection should be stored at room temperature up to 30°C and administered within 12 hr after preparation.
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.
Antacids, Antireflux Agents & Antiulcerants
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