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      Country of origin: INDIA

      Seller Information

      10 Units/pack

      MRP 598.96

      Inclusive of all Taxes

      FLAT 20% OFF On bills above 1000.0
      FIBRISTONE 25MG TAB Out of Stock Get Notified

      Fibristone 25MG tablet
      Uses and Benefits

      Uses and Benefits

      Fibristone 25MG tablet contains Mifepristone which belongs to the category of progestins, is used for terminating pregnancies which are less than 10 weeks old. It is used for labor induction in case of foetal death or before surgical procedures are performed to terminate a pregnancy. It is also used for the management of high blood glucose levels in patients with high level of cortisol (Cushing’s syndrome) coupled with type 2 diabetes mellitus or glucose intolerance. However, the uses mentioned here are not comprehensive, there may be other conditions for which the medication may be used upon your doctor’s discretion.

      Composition

      Composition

      The active ingredient of Fibristone 25MG tablet is Mifepristone 25 MG

      Mechanism of Action of Drugs

      Mechanism of Action of Drugs

      Mifepristone is a synthetic steroid which blocks the effects of progesterone (a natural female hormone) by competitively binding to intracellular progesterone receptor, helping in termination of pregnancy. Without progesterone, the lining of uterus breaks as it does during menstrual period and stops the growth of pregnancy. It also blocks cortisol receptors and helps in controlling high blood glucose levels in patients with Cushing’s syndrome.

      Contraindications and Cautions

      Contraindications and Caution

      Patients with following conditions are suggested to seek advice from their healthcare professionals before taking Fibristone 25MG tablet:

      • Hypersensitivity to any of the ingredients used in the tablet
      • Confirmed or suspected ectopic pregnancy
      • Undiagnosed adrenal mass
      • Chronic adrenal failure
      • Uncontrolled severe asthma
      • Porphyria
      • Haemorrhagic disorder
      • History of unexplained vaginal bleeding, endometrial hyperplasia or endometrial carcinoma
      • Caution:
      • Cardiovascular disorders
      • Anaemia
      • Severe vaginal bleeding
      • Hyperglycaemia
      • Risk of infections
      • Hepatic and renal impairment
      • Hypokalaemia
      • Use of glucocorticoids medicine
      • Lactation
      Side Effects

      Side and Adverse Effects

      Fibristone 25MG tablet is usually well tolerated when used in the prescribed dosage guidelines. Most side effects are temporary and usually subsides on their own. However, consult your doctor if they persist for a longer duration. You may experience one or more of the following symptoms:

      • Breast pain/tender breasts
      • Nausea
      • Vomiting
      • Uterine cramps
      • Infection following abortion
      • Painful, heavy or irregular periods
      • Headache
      • Abdominal pain and cramps
      • Diarrhoea
      • Dizziness
      • Unusual weakness and tiredness
      • Loss of strength
      How to Use

      How to Use

      Take Fibristone 25MG tablet as instructed by your doctor. Swallow the tablet whole with water, immediately after opening it from the strip. Do not break or crush or chew the tablet.
      Avoid missing or forgetting the dose. If you do, take it as soon as you remember; but if it’s almost time for your next dose, skip it and take it according to your normal schedule. Don’t swallow two doses at the same time which is dangerous to your health.
      The tablet can be taken with or without food. Take the tablet at the same time every day as it helps to maintain a consistent level of medicine in the body.
      Do not change the dose or stop taking the medicine before completion of the course or without consulting your doctor. Continue to use this drug until completion of the maximum amount suggested.

      Overdosage

      Avoid taking more than the recommended dosage. In case of accidental overdose, promptly seek medical advice. Depending on the dosage of Fibristone 25MG tablet, symptoms vary in individuals, you may experience one or more of the following symptoms:

      • Hypokalaemia
      • Dry mouth
      • Peripheral oedema
      • Abdominal cramps
      • Pain extremity
      • Hypertension
      Warnings and Precautions

      Warnings and Precautions

      Take Fibristone 25MG tablet only on the advice of medical practitioner. Dosage adjustments or complete avoidance of the medication may be required in the following conditions:

      Kidney:

      Since there is not enough reliable information about the safety of taking this medicine for renal patients, consult your doctor if you an impairment of normal kidney function and stay on the safe side.

      Liver:

      Since there is not enough reliable information about the safety of taking this medicine for hepatic patients, consult your doctor if you an impairment of normal liver function and stay on the safe side.

      Pregnancy:

      It is not recommended during pregnancy as it is known to cause harm to the fetus. We suggest you to consult your doctor before consuming this medicine.

      Lactation:

      This medicine is not considered safe to use in nursing mothers unless the potential benefits outweigh the risks involved. Since the effect of the medicine on infants is not clearly established, we recommend that you to consult your doctor before consuming the tablet.

      Alcohol:

      Interaction of alcohol with this tablet is unknown. Any symptoms of abnormal reactions after taking the medicine should be reported to your doctor immediately.

      Driving:

      The tablet may decrease alertness, affect your vision and make you feel dizzy, light headedness. Do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

      Food:

      Avoid grape fruit juice.

      Drug Interactions:

      All medicines interact differently for person to person. Inform your doctor or pharmacist if you are taking any other medicines which includes over-the-counter drugs, herbal tonics, supplements and medicines that you buy without a prescription. Alert your doctor if you are taking Fibristone 25MG tablet with carbamazepine, rifampicin, efavirenz, fluconazole, lorazepam, phenobarbital, phenytoin, ritonavir, nevirapine, citalopram, fluvoxamine, triazolam, testosterone.

      Precautions
      • Do not use this medicine past the expiry date
      • Store at room temperature (25-30 degree Celsius)
      • Keep the medicine out of reach of children
      FDA Pregnancy Category

      FDA Pregnancy Category

      Category X: Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits


      Drug Composition information
      What is Mifepristone for:

      This medication is a synthetic steroid, used alone or together with another medication, to end an early pregnancy (within 7 weeks of the start of a womans last menstrual period). It blocks the hormone needed for pregnancy to continue.

      How does Mifepristone work:

      It is also indicated for high blood sugar levels (hyperglycemia) in adults with endogenous Cushing’s syndrome.

      How should Mifepristone be used:

      If using to end pregnancy: - This drug must be taken exactly as you have been told. - If using for high blood sugar: - Take with food. Swallow whole. Do not chew, break, or crush.

      Common side effects of Mifepristone :

      Dizziness. Headache. Feeling tired or weak. Belly pain. Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. Not hungry. Loose stools (diarrhea). Vaginal bleeding. There may be more bleeding than from a heavy period. Low blood sugar. Signs include anger, shaking, a fast heartbeat, confusion, or sweating. Keep hard candies, glucose tablets, liquid glucose, or juice on hand for low blood sugar.

      What do I do if I miss a dose

      If using to end pregnancy: - Call your doctor to find out what to do. If using for high blood sugar: - Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.

      What precautions should I take when taking Mifepristone :

      If you have an allergy to mifepristone or any other part of this drug. Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you are taking a blood thinner or are on a long-term steroid, such as prednisone. If you are breast-feeding. If using to end pregnancy: - If you have any of these health problems: Adrenal failure, bleeding problems, porphyrias, or pregnancy where the fertilized egg was not in a normal position. If you have an IUD (intrauterine device) in place. If you are not able to follow what your doctor gives you or you are not able to get to an ER (emergency room) if you need one. If you are more than 7 weeks pregnant. If using for high blood sugar: - If you have any of these health problems: - Change in the cells lining your uterus, endometrial cancer, or vaginal bleeding. If you do not have Cushing’s syndrome. If you are pregnant or may be pregnant.

      When do I need to seek medical help

      If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Signs of infection. These include a fever of 100.5°F (38°C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain. Bleeding a lot (soaking 1 pad per hour). Very bad dizziness or passing out. A fast heartbeat. Signs of low blood pressure. Signs of low blood sugar. Very bad belly pain. Very upset stomach or throwing up. Very loose stools (diarrhea). Weakness with or without belly pain and fever. Feeling very tired or weak. For women, period changes. These include lots of bleeding, spotting, or bleeding between cycles. Very bad muscle pain or weakness. Any rash. Side effect or health problem is not better or you are feeling worse.

      Can I take Mifepristone with other medicines:

      Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.

      Are there any food restrictions

      Avoid Alcohol

      How do I store Mifepristone :

      Store in a cool, dry place away from the reach of children. - Medicines must not be used past the expiry date.

      Pregnancy Category

      Category X : Studies in animals or humans have demonstrated fetal abnormalities andor there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.

      Therapeutic Classification

      Drugs Acting on the Uterus


      Frequently Asked Questions

      Frequently Asked Questions
      Q1. What is the use of the Fibristone 25MG tablet?

      It contains Mifepristone which belongs to the category of progestins, is used for terminating pregnancies which are less than 10 weeks old. It is used for labor induction in case of foetal death or before surgical procedures are performed to terminate a pregnancy. It is also used for the management of high blood glucose levels in patients with high level of cortisol (Cushing’s syndrome) coupled with type 2 diabetes mellitus or glucose intolerance.

      Q2. What are the side effects of the Fibristone 25MG tablet?

      This medicine is well tolerated when taken in prescribed dosage guidelines. Most common side effects breast pain/tender breasts, nausea, vomiting, uterine cramps, infection following abortion, painful, heavy or irregular periods, headache, abdominal pain and cramps, diarrhoea, dizziness, unusual weakness and tiredness, loss of strength.

      Q3. Should we take Fibristone 25MG tablet with food or without food?

      The tablet can be taken with or without food.

      Q4. What are the precautions to be followed while taking the Fibristone 25MG tablet?

      If you ever had impaired kidney function, severe liver impairment or heart disease, let your doctor know before taking this medicine. Inform your doctor about all the medicines you take to ensure that you are healthy. This medicine is contraindicated in patients with hypersensitivity to any of the ingredients used in the tablet, confirmed or suspected ectopic pregnancy, undiagnosed adrenal mass, chronic adrenal failure, uncontrolled severe asthma, porphyria, haemorrhagic disorder, history of unexplained vaginal bleeding, endometrial hyperplasia or endometrial carcinoma. Caution is advised among patients with cardiovascular disorders, anaemia, severe vaginal bleeding, hyperglycaemia, risk of infections, hepatic and renal impairment, hypokalaemia, use of glucocorticoids medicine, children, lactation.

      Q5. Does Fibristone 25MG tablet make you sleepy?

      This medicine may decrease alertness, cause impaired judgement, affect your vision and make you feel dizzy. Do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

      Q6. Is Fibristone 25MG tablet harmful? What does an overdose of Fibristone 25MG tablet lead to?

      The tablet is usually well tolerated when taken in the recommended dosage guidelines. Overdose of this medicine leads to hypokalaemia, dry mouth, peripheral oedema, abdominal cramps, pain extremity, hypertension.

      Q7. Can I take Fibristone 25MG tablet during pregnancy?

      It is not recommended during pregnancy as it is known to cause harm to the fetus. We suggest you to consult your doctor before consuming this medicine.

      Q8. Can Fibristone 25MG tablet be taken without a doctor’s prescription?

      No, do not take the medicine without doctor’s prescription.

      Q9. Is it okay to drink alcohol while I am on the Fibristone 25MG tablet?

      Interaction of alcohol with this tablet is unknown. Any symptoms of abnormal reactions after taking the medicine should be reported to your doctor immediately.

      Q10. How to store Fibristone 25MG tablet?

      Store the medicine at room temperature (20-30 degree Celsius) in a cool and dry place. Keep the tablet according to the instructions mentioned on the pack or label. Store the medicine in the container or the pack it came in, tightly closed.

      Q11. If I have trouble swallowing Fibristone 25MG tablet, can I mix it in water and drink it?

      This tablet is designed to be swallowed with water. If you take them in a way they weren’t intended to be used, you could experience an overdose if the active constituent enters the blood stream too quickly. Alternatively, if it enters your body too slowly, it may never achieve a high enough concentration to be completely functional.

      Q12. Can we give Fibristone 25MG tablet to children?

      This tablet is strictly not recommended for children between 12-18 years of age.

      Q13. By when should I start seeing the results of the Fibristone 25MG tablet?

      The amount of time required for the tablet to show its effect in the body is within 1-2 hours of administration.

      Q14. How long does the effect of Fibristone 25MG tablet last?

      The duration for which this medicine remains active in the body is for about 7-10 days.

      Q15. Can we take Fibristone 25MG tablet daily? If yes, how many tablets can we take everyday?

      Medicines should always be taken under medical supervision. Take the medicine exactly as prescribed by your doctor: for dosage and duration. Most recommended dose is one tablet a day.

      Q16. For how many days should I take the Fibristone 25MG tablet?

      The number of days that any medicine must be taken varies from patient to patient; and case to case. So always stick to your doctor’s suggestion about how many days to take this medicine.

      Q17. When should I take Fibristone 25MG tablet?

      Take the medicine exactly as prescribed by your doctor for the dosage and duration.

      Note: All of the above information is for reference purpose only. It is always recommended that you consult a medical professional.

      Seller Information
      Manufactured By

      JAGSONPAL PHARMACEUTICALS PVT LTD

      t-210 j,shahpur jat,new delhi-110049 at kh no 596/1,roorkee-dehradun highway,kishanpur,roorkee-247667(u.k.)

      Packed By

      JAGSONPAL PHARMACEUTICALS PVT LTD

      t-210 j,shahpur jat,new delhi-110049 at kh no 596/1,roorkee-dehradun highway,kishanpur,roorkee-247667(u.k.)

      Applicable Offers

      • 20% Discount
        On prescription medicines, orders above Rs 1000 T & C

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