Country of origin: INDIA
| FIVE DERM 15GM CREAM |
Five Derm 15GM cream is combination of medicines used to treat various skin infections caused by fungus and bacteria and certain yeasts. It is used to treat infections caused by Epidermophyton floccosum, Trichophyton spp., and Microsporum spp. These infections caused could be infection of feet, ringworm infection, or infection in groin and buttocks. It is used for the topical treatment of tinea corporis, tinea cruris and tinea pedis and in the treatment of cutaneous candidiasis, seborrheic dermatitis and scalp psoriasis, characterised by symptoms such as red, scaly, itchy patches of skin on the scalp and persistent dandruff. This cream is also used in the treatment of cryptococcal infection and infections caused by Blastomyces, Aspergillus, histoplasma. However, the uses of this cream mentioned here are not exhaustive, there may be other conditions for which the medication may be used upon your doctor’s discretion.
The active ingredients of Five Derm 15GM cream are Clobetasol propionate (0.05% W/W), Iodochlorhydroxyquinoline (1% W/W), Ketoconazole (2% W/W), Neomycin (0.1% W/W) and Tolnaftate (2% W/W)
Clobetasol propionate is a steroid which works by blocking the production of prostaglandins (chemical messengers) that make skin red, swollen and itchy. Iodochlorhydroxyquinoline is an antibiotic that kills bacteria and fungus by damaging the DNA.
Ketoconazole and Tolnaftate are anti-fungal drugs that changes the permeability of the cell wall of the fungal cells and prevents their growth. It binds to the phospholipids of the membrane and inhibits the fungal CYP450 activity, thereby decreasing ergosterol biosynthesis that are essential for the development of the cell membrane. This results in the death of cells due to the loss of intracellular sections.
Neomycin is an antibiotic that stops the growth of bacteria on the skin by preventing the synthesis of essential proteins required by bacteria to carry out its vital functions.
Patients with following conditions are suggested to seek advice from their healthcare professionals before using Five Derm cream.
Caution:
The following side effects may or may not occur during the usage of Five Derm cream. It is usually well tolerated when used in the prescribed dosage guidelines. More common ones include:
Rare but more serious adverse effects may include:
Use Five Derm cream as instructed by your doctor. Do not use this cream for durations shorter or longer than suggested by your doctor.
Continue to use this drug until completion of the maximum amount prescribed, even though the symptoms disappear after medicine has begun. Stopping the medication too early can allow the growth of the microbes to begin, which can lead to an infection relapse.
Clean and dry the affected area. Apply a thin layer of Five Derm cream twice daily or as advised by your doctor and gently rub on the affected areas. Avoid getting this cream in contact with open wounds, eyes, mouth and nose.
Avoid applying the Five Derm cream more than required. In case of overdose, promptly seek medical advice. Consult your doctor if you experience any allergic reaction. Symptoms of over dose may include:
Use Five Derm cream on the advice of your medical practitioner. Complete avoidance of the cream may be required in the following conditions:
Since there is not enough reliable information about the safety of using this cream for renal patients, consult your doctor if you have renal problems and stay on the safe side.
Since there is not enough reliable information about the safety of taking this cream for hepatic patients, consult your doctor if you have liver problems and stay on the safe side.
Five Derm cream is generally considered safe to use in pregnant women unless the potential benefits outweigh the risks involved. Animal studies have shown no or low adverse effects on fetus; however, there are limited human studies. It is recommended that you consult your doctor before using this cream.
This medicine is generally considered safe to use in nursing mothers unless the potential benefits outweigh the risks involved. Since the effect of the medicine on infants is not clearly established, we recommend that you to consult your doctor before using the cream.
Since there is not enough reliable information about the interaction of Five Derm cream with alcohol, consult your doctor and stay on the safe side.
Five Derm cream does not cause drowsiness or dizziness. Since there is not enough reliable information about the safety of using this cream, consult your doctor and stay on the safe side.
There are no known food interactions with Five Derm cream.
There are no known drug interactions with Five Derm cream. Check with your medical professional about all the possible interactions of the drugs you’re taking.
Category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
This medication is a corticosteroid, prescribed for skin disorders including eczema, psoriasis and lichen sclerosis. The medication reduces the action of chemicals that causes inflammation and redness.
Clobetasol stops or lowers irritation and swelling.
Apply a thin layer to the affected skin area twice daily, rub gently. It comes as a cream or ointment to apply over the affected area.
Skin irritation
Take a missed dose as soon as you think about it. - If it is close to the time for your next dose, skip the missed dose and go back to your normal time. - Do not take 2 doses at the same time or extra doses.
Alert your doctor if you are pregnant or become pregnant while being treated with Clobetasol. Let your doctor know if you are breastfeeding. Do not apply Clobetasol on the nipples if you are breastfeeding. Do not apply on skin that is broken or infected. Do not apply on skin that is discharging fluid or pus. Do not apply on your face, groin or armpits unless instructed by your doctor.
If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Signs of infection. These include a fever of 100.5°F (38°C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain. Feeling very tired, weak, or touchy; trembling; having a fast heartbeat, confusion, sweating, or dizziness if you missed a dose or recently stopped this drug. Very bad skin irritation. Any rash. Side effect or health problem is not better or you are feeling worse.
Inform your doctor if you are using any other creams, ointments or lotions on the affected area. - Always inform your doctor and pharmacist if you are taking any other medicines, including herbal tonics, supplements and medicines that you buy without a prescription.
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Store it at room temperature.
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Topical Corticosteroids
Five Derm 15GM cream is amalgamation of medicines used to treat skin infections caused by fungus and bacteria and certain yeasts. It is used to treat infections caused by Epidermophyton floccosum, Trichophyton spp., and Microsporum spp. These infections caused could be infection of feet, ringworm infection, or infection in groin and buttocks. It is used for the topical treatment of tinea corporis, tinea cruris and tinea pedis and in the treatment of cutaneous candidiasis, seborrheic dermatitis and scalp psoriasis, characterised by symptoms such as red, scaly, itchy patches of skin on the scalp and persistent dandruff. This cream is also used in the treatment of cryptococcal infection and infections caused by Blastomyces, Aspergillus, histoplasma.
Use the medicine exactly as prescribed by your doctor for the dosage and duration.
Use the medicine exactly as prescribed by your doctor for the dosage and duration.Depending on the severity of infection, apply the cream 1-3 times a day.
The cream is well tolerated when used in prescribed dosage guidelines. Most common side effects include itching, peeling, burning, irritation, blistering, redness at the application site and skin rash. Its use may also lead to extreme but uncommon side effects dry skin, severe itching, pruritis, stinging.
Five Derm cream does not cause drowsiness or dizziness. Since there is not enough reliable information about the safety of using this cream, consult your doctor and stay on the safe side.
Apply the cream exactly as prescribed by your doctor for the dosage and duration. Stopping the medication too early can allow the growth of the microbes to begin, which can lead to an infection relapse.
Five Derm cream is usually well tolerated when used in the recommended dosage guidelines. Over dose of the medicine may lead to swelling, burning sensation, severe itching, eczema, paraesthesia of skin.
Usage of the cream does not depend on food.
If you ever had impaired kidney function, liver impairment or heart disease, let your doctor know before using this medicine. Inform your doctor about all the medicines you take to ensure that you are healthy. Caution is advised among patients who have an allergy to any components used in the cream, patients with ocular lesions, tuberculosis of skin, broken skin and perforated tympanic membrane.
This cream is not recommended for children below 2 years of age unless prescribed since the safety and efficacy of use are not clinically established.
The duration for which this medicine remains active on the body is not clinically determined.
Five Derm cream is considered safe to use in pregnant women unless the potential benefits outweigh the risks involved. Animal studies have shown no or low adverse effects on fetus; however, there are limited human studies. It is recommended that you consult your doctor before using this cream.
To get the most benefits, use the medicine preferably at the same time every day and you should not quit unless your doctor suggests.
No, do not use the medicine without doctor’s prescription.
Since there is not enough reliable information about the interaction of Five Derm cream with alcohol, consult your doctor and stay on the safe side.
Store the medicine at room temperature (15-30 degree Celsius) in a cool and dry place. Keep the cream according to the instructions mentioned on the pack or label. Store the medicine in the container or the pack it came in, tightly closed.
Five Derm cream must be used for external purpose only. Applying this cream to open cavities may result in severe irritation and redness.
Continue to use the medicine until completion of the maximum amount prescribed, even though the symptoms disappear after medicine has begun. Stopping the medication too early can allow the growth of the microbes to begin, which can lead to an infection relapse.
The amount of time required for this medicine to show its action is not clinically determined. You will start to feel better in 1-2 days after using the cream. But continue to use the cream until completion of the maximum amount prescribed, even though the symptoms disappear after medicine has begun.
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