This medication is a pyrimidine synthesis inhibitor, prescribed for rheumatoid arthritis. The medication reduces joint damage and enhances physical activity.
It blocks certain enzymes responsible for abnormal tissue development or growth.
It comes as a tablet to take by mouth with or without food. Adult: Oral- Rheumatoid arthritis; Psoriatic arthritis- Loading dose: 100 mgday for 3 days. Maintenance: 10-20 mgday.
Lung infection. Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. Loose stools (diarrhea). Hair loss. Hair most often grows back when this drug is stopped. Harm to the liver may rarely happen.
Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.
If you have an allergy to leflunomide or any other part of this drug. - Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. - Do not use this drug if you are pregnant and do not get pregnant. Use birth control that you can trust. At the end of care, you will need to get rid of the extra leflunomide in your body. Taking a drug called cholestyramine 3 times a day for 11 days will get rid of most of the drug. Talk with your doctor if you want to get pregnant. You will need to have blood tests showing that your body is free of leflunomide before you stop taking birth control. If you are breast-feeding.
If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.
Store in a cool, dry place away from the reach of children. - Medicines must not be used past the expiry date.
Category X : Studies in animals or humans have demonstrated fetal abnormalities andor there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
Disease-Modifying Anti-Rheumatic Drugs (DMARDs)
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