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FLUZO 150MG TAB

Fluzo Tablet 150mg
Uses and Benefits

Uses and Benefits

Fluzo Tablet 150mg is used to treat fungal infections such as vaginal yeast infections, systemic candida infections, esophageal and oropharyngeal candidiasis, cryptococcal meningitis, UTI by candida, and peritonitis caused by candida. However, the uses mentioned here are not exhaustive. There may be other conditions for which this medication may be used upon a doctor’s discretion.

Composition

Composition

The active ingredient of Fluzo Tablet 150mg is Fluconazole 150mg.

Mechanism of Action of Drugs

Mechanism of Action of Drugs

Fluconazole inhibits the conversion of lanosterol to ergosterol which is necessary for the fungal cell wall synthesis. Thus how inhibits fungal infection.

Contraindications and Cautions

Contraindications and Caution

Patients with the following conditions are suggested to seek advice from their health care professionals before taking the Fluzo Tablet 150mg:

  • Hypersensitivity to any of the components used in the Fluzo Tablet 150mg such as Fluconazole
  • Caution:
  • Electrolyte abnormalities
  • QT prolongation
  • QT prolongation family history
  • Congenital long QT syndrome
  • Torsades de Pointes history
  • Ventricular arrhythmias
  • Bradycardia
  • Recent MI
  • CHF
  • Renal impairment
  • Hepatic impairment
Side Effects

Side and Adverse Effects

The following side effects may or may not occur during the usage of Fluzo Tablet 150mg. It is generally well tolerated when taken in the prescribed dosage guidelines. More common ones are generally mild and may include:

  • Nausea
  • Headache
  • Rash
  • Vomiting
  • Abdominal pain
  • Diarrhea
  • Dyspepsia
  • Taste changes
  • Dizziness
  • ALT, AST elevated

Rare but more serious adverse effects may include:

  • Hepatotoxicity
  • Seizures
  • Leukopenia
  • Agranulocytosis
  • Thrombocytopenia
  • Angioedema
  • Anaphylaxis
  • Stevens-johnson syndrome
  • Toxic epidermal necrolysis
  • QT prolongation
  • Torsades de pointes
  • Adrenal insufficiency
How to Use

How to Use

Do not exceed the dose prescribed by your doctor.
Swallow the Fluzo tablet immediately after opening it from the strip. Do not break or chew the Fluzo Tablet.
Avoid missing/forgetting a dose. If you do, take it as soon as you remember; but if it is almost time for your next dose, skip it and take it according to your normal schedule. Don’t consume two doses at the same time which may be dangerous to your health.
Fluzo Tablet may be taken with or without food.
Take the medication at the prescribed time and dosage.

Overdosage

Avoid taking more than the prescribed dosage. In case of an accidental overdose, promptly seek medical advice. Depending on the dosage, symptoms may vary but you may experience any one or more of the following signs or symptoms:

  • Hallucination
  • Paranoid behavior
Warnings and Precautions

Warnings and Precautions

Take Fluzo Tablet 150mg only on the advice of a medical practitioner. Dosage adjustment or complete avoidance of the medication may be required in the following conditions:

Kidney:

Caution advised among people with renal problems. If you have any, consult your doctor before the consumption of this Fluzo Tablet.

Liver:

Caution advised among people with hepatic problems. If you have any, consult your doctor before the consumption of this Fluzo Tablet.

Pregnancy:

Safety during pregnancy has not yet established. Therefore, inform your doctor if you are pregnant or plan to become pregnant during the treatment.

Lactation:

May be used during breastfeeding, no known risk of infant harm. However, the risk of GI upset and diarrhea to the breastfed infant is expected based on limited human data. Therefore, inform your doctor before taking the tablet.

Drug Interactions:

Caution always advised when used with other medicine(s). Therefore, inform your doctor about your current list of medicine(s) during the treatment (if any).

Precautions
  • Keep the medicine out of sight and reach of children.
  • Store at room temperature away from heat and moisture.
  • Do not use the Fluzo Tablet 150mg beyond its expiry.
FDA Pregnancy Category

FDA Pregnancy Category

Category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant the use of the drug in pregnant women despite potential risks.


Drug Composition information
What is Fluconazole for:

This medication is an antifungal agent, prescribed for vaginal candidiasis, pneumonia, meningitis and fungal infections of the mouth, throat, liver, kidneys, heart, urinary tract and abdomen. It works by slowing the growth of fungi that cause infection.

How does Fluconazole work:

Fluconazole works to harm the yeast and fight the infection.

How should Fluconazole be used:

PO- The recommended dose range is 50-400 mg daily. It comes as a tablet to take by mouth, with or without food once a day. It also comes as eye drops to instill into affected eyes.

Common side effects of Fluconazole :

Headache. Belly pain. Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar- free gum may help. Loose stools (diarrhea).

What do I do if I miss a dose

Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.

What precautions should I take when taking Fluconazole :

If you have an allergy to fluconazole or any other part of this drug. Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs

When do I need to seek medical help

If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Very bad belly pain. Very upset stomach or throwing up. Very loose stools (diarrhea). Not able to eat. Dark urine or yellow skin or eyes. Feeling very tired or weak. For women, if you get pregnant while taking this drug. Any rash. Side effect or health problem is not better or you are feeling worse.

Can I take Fluconazole with other medicines:

Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.

Are there any food restrictions

Avoid Alcohol

How do I store Fluconazole :

Store it at controlled room temperature (30°C), and in an airtight container. Keep away from children.

Pregnancy Category

Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Therapeutic Classification

Antifungals

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