This medication is an anticonvulsant drug, prescribed for epilepsy and bipolar disorder, as well as trigeminal neuralgia. It works by reducing or blocking certain responses in the brain.
Carbamazepine calms the brain. - It helps steady mood.
Adult: PO Epilepsy Initial: 100-200 mg 1-2 timesday, may increase slowly. Maintenance: 0.8-1.2 gday in divided doses. Max: 2 gday. Prophylaxis of bipolar disorder Initial: 400 mgday in divided doses may increase slowly. Maintenance: 400-600 mgday. Max: 1.6 gday. Trigeminal neuralgia Initial: 100 mg 1-2 timesday, may increase slowly. Maintenance: 400-800 mgday in 2-4 divided doses. Max: 1.2 gday. Rectal Epilepsy -250 mg 6 hourly. Children 6-12 years of age – Initial- Either 100 mg b.i.d. for tablets or XR tablets, or ½ teaspoon q.i.d. for suspension (200 mgday). Children 6 years of age – Initial- 10-20 mgkgday b.i.d. or t.i.d. as tablets, or q.i.d. as suspension. It comes as a capsule to take by mouth, with food.
Feeling lightheaded, sleepy, having blurred eyesight, or a change in thinking clearly. Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how this drug affects you. Change in balance. Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. Dry mouth. Good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. See a dentist often.
Take a missed dose as soon as you think about it. - If it is close to the time for your next dose, skip the missed dose and go back to your normal time. - Do not take 2 doses at the same time or extra doses. - Do not change the dose or stop this drug. - Talk with the doctor.
Alert your doctor if you are pregnant or breastfeeding. - Alert your doctor if you have blood disorders or if you are allergic to a type of antidepressants known as tricyclic antidepressants. - Alert your doctor if you are currently taking or have taken antidepressants known as monoamine oxidase inhibitors (MAOIs) such as isocarboxacid, phenelzine and tranylcypromine in the last 14 days.
If you think there was an overdose, call your local poison control center or ER right away. - Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. - Signs of infection. These include a fever of 100.5°F (38°C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain. - Signs of low mood (depression), thoughts of killing yourself, nervousness, emotional ups and downs, thinking that is not normal, anxiety, or lack of interest in life. - Very bad dizziness or passing out. - Change in thinking clearly and with logic. Big change in balance. Very upset stomach or throwing up. - Any bruising or bleeding. Yellow skin or eyes. Not able to eat. Feeling very tired or weak. If seizures are worse or not the same after starting this drug. Very bad mouth irritation. Very bad skin irritation. Any rash. Side effect or health problem is not better or you are feeling worse.
Do not take Carbamazepine if you are currently taking or have taken antidepressants known as monoamine oxidase inhibitors (MAOIs) such as isocarboxacid, phenelzine and tranylcypromine in the last 14 days. Alert your doctor if you are taking any other medicines, especially those listed here: - other epilepsy medicines. - antidepressants such as fluoxetine, fluvoxamine, sertraline, paroxetine, mianserin. - mood medicines such as nefazodone, haloperidol, risperidone or lithium. - blood-thinning medicines such as warfarin. - asthma medicines such as theophylline - antifungal medicines such as ketoconazole, itraconazole, fluconazole, miconazole. - worm medicines such as albendazole, mebendazole (only when used long-term). - antibiotics such as doxycycline, erythromycin, clarithromycin. - birth control pills. - sleeping pills. - heart medicine such as diltiazem, verapamil. - cholesterol medicine such as simvastatin. - TB medicine, especially isoniazid. - cancer medicines. - HIV (AIDS). medicines such as ritonavir. - other medicines such as danazol, ciclosporin. - As Carbamazepine may reduce the effectiveness of birth control pills, ask your doctor about the use of additional birth control methods. Always inform your doctor and pharmacist if you are taking any other medicines, including herbal tonics, supplements and medicines that you buy without a prescription.
Avoid alcohol, grapefruit juice and evening primrose oil.
Store it at room temperature.
Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Anticonvulsants, Drugs For Neuropathic Pain
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