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      Mfg/Mkt: ipca laboratories ltd

      FOLITRAX 20MG 1ML INJ

      Country of origin: INDIA

      Seller Information

      1 Units/pack

      MRP 104.10

      Inclusive of all Taxes

      FLAT 20% OFF On bills above 1000.0
      FOLITRAX 20MG 1ML INJ

      Folitrax 20MG 1ML injection
      Uses and Benefits

      Uses and Benefits

      Folitrax 20MG 1ML injection is used to treat life-threatening conditions like severe rheumatoid arthritis (an autoimmune disease that affects the smaller joints in the body characterized by loss of joint function, progressive bone destruction and damage) and psoriatic arthritis, a form of arthritis associated with psoriasis (characterized by red inflamed skin, often covered by scales) and certain types of cancers that occur in the woman’s uterus. This medicine slows down the progression of the disease and provides relief from pain, swelling and redness. However, the uses mentioned here are not comprehensive, there may be other conditions for which the medication may be used upon your doctor’s discretion.

      Composition

      Composition

      The active ingredient of Folitrax 20MG 1ML injection is Methotrexate 20MG/ Injection

      Mechanism of Action of Drugs

      Mechanism of Action of Drugs

      Methotrexate acts on cells involving in immune function that are responsible for the swelling and joint damage. It also blocks the action of specific substances (cyclooxygenase-2) in the body that are responsible for causing inflammation (pain, redness, swelling) and other associated complications. In psoriasis, this medicine works by slowing down the rapid growth of skin cells by interfering with the DNA synthesis.

      Contraindications and Cautions

      Contraindications and Caution

      Patients with following conditions are suggested to seek advice from their healthcare professionals before using Folitrax 20MG 1ML injection:

      • Hypersensitivity to any of the ingredients used in the injection
      • Pre-existing blood disorders
      • Active gastrointestinal ulcer disease
      • Alcoholism
      • Compromised immune function
      • Severe renal or hepatic impairment
      • Pregnancy and lactation
      • Caution:
      • Concurrent vaccination with live vaccines
      • Folic acid deficiency
      • Bone marrow suppression
      • Dehydrated or debilitated patients
      • Children and elderly
      Side Effects

      Side and Adverse Effects

      Folitrax 20MG 1ML injection is usually well tolerated when used in the prescribed dosage guidelines. Most side effects are temporary and usually subsides on their own. However, consult your doctor if they persist for a longer duration. You may experience one or more of the following symptoms:

      • Injection site reactions (swelling, redness, pain)
      • Nausea or vomiting
      • Abdominal pain
      • Mouth sores
      • Diarrhoea
      • Indigestion
      • Loss of appetite
      • Joint pain
      • Dizziness
      • Unusual bleeding
      • Blurred vision
      • Pale skin
      • Fever or chills
      How to Use

      How to Use

      Do not self-administer Folitrax 20MG 1ML injection, your nurse or trained physician will give you the medicine. Avoid missing or forgetting the dose. If you do, take it as soon as you remember; but if it’s almost time for your next dose, skip it and take it according to your normal schedule.
      The injection can be taken with or without food. Do not change the dose or stop taking the medicine before completion of the course or without consulting your doctor. Continue to use this drug until completion of the maximum amount suggested even though the symptoms disappear after the medicine has begun.

      Overdosage

      Since this injection will be given by doctor or nurse, therefore it is less likely that you will receive overdose of the medicine. Depending on the dosage of Folitrax 20MG 1ML injection, symptoms vary in individuals, you may experience one or more of the following symptoms:

      • Blood disorders
      • Gastrointestinal reactions (ulcer and bleeding, mucositis)
      • Headache
      • Increased intracranial pressure
      • Renal failure
      • Aplastic anaemia
      Warnings and Precautions

      Warnings and Precautions

      Use this injection on the advice of medical practitioner. Dose adjustments or complete avoidance of the Folitrax 20MG 1ML injection may be required in the following conditions:

      Kidney:

      Caution is advised among people with kidney problems. Close monitoring of kidney function and adjustments of dose of the medicine may be needed based on the clinical condition of the patient. If you have any renal problems, it is highly recommended that you consult doctor before the taking this injection.

      Liver:

      Extreme caution is advised among people with liver problems. Dose adjustments may be needed. If you have any hepatic problems, we recommend you to consult your doctor before taking this injection. However, this injection is not recommended in patients with moderate to severe hepatic impairment.

      Pregnancy:

      This medicine is not recommended for use during pregnancy as it is known to cause harm to the fetus. Please consult your doctor before taking this medicine.

      Lactation:

      This medicine is not considered safe to use in nursing mothers unless the potential benefits outweigh the risks involved. Limited human data suggests that the medication may pass into the breastmilk and harm the infant. Consult your doctor immediately if the baby shows signs of increased sleepiness, breathing problems or difficulty in breast feeding.

      Alcohol:

      Consumption of alcohol with this injection is not recommended as it increases the risk of liver damage. If you notice any unusual or abnormal reactions after taking the medicine, report to your doctor immediately.

      Driving:

      This injection may decrease alertness, cause impaired judgement, affect your vision and make you feel dizzy. If you notice any abnormal reactions after taking the medicine do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

      Food:

      Milk rich products should be avoided.

      Drug Interactions:

      Inform your doctor or pharmacist if you are taking any other medicines which includes over-the-counter drugs, herbal tonics, supplements and medicines that you buy without a prescription. Alert your doctor if you are taking Folitrax 20MG 1ML injection with live vaccines, cholestyramine, rifampicin, ciprofloxacin, omeprazole, cisplatin, antibiotics, folic acid, chloramphenicol, retinoids, azathioprine, warfarin, NSAIDs, teriflunomide, chlorpropamide.

      Precautions
      • Do not use this injection post the expiry date
      • Keep the medicine out of reach of children
      • Store at cool temperature (2-8 degree Celsius), do not freeze
      FDA Pregnancy Category

      FDA Pregnancy Category

      Category X: Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.


      Drug Composition information
      What is Methotrexate for:

      This medication is an antimetabolite, curative in choriocarcinoma (cancer of the tissue that normally would develop into placenta). It is also used in other cancers like blood, breast and lung cancers.

      How does Methotrexate work:

      It is also used to suppress immunity in conditions such as psoriasis and rheumatoid arthritis.

      How should Methotrexate be used:

      It comes as a tablet to take by mouth, with or without food.It also comes as a solution for injection to be administered by a healthcare provide into a large muscle.

      Common side effects of Methotrexate :

      Anemia, low white blood cell count, and low platelet count. Chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu. Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. Not hungry. Loose stools (diarrhea). Mouth irritation or sores. Using a soft toothbrush or cotton swabs and rinsing the mouth may help. Do not use mouth rinses that have alcohol in them. Sore throat. Headache. Hair loss. Hair most often grows back when this drug is stopped. Kidney failure may rarely happen. Harm to the liver may rarely happen. Harm to the lungs may rarely happen. Other kinds of cancer may rarely happen later in life.

      What do I do if I miss a dose

      Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.

      What precautions should I take when taking Methotrexate :

      If you have an allergy to methotrexate or any other part of this drug. Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you are breast-feeding.

      When do I need to seek medical help

      If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Signs of infection. These include a fever of 100.5°F (38°C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain. Chest pain or pressure. Trouble breathing. Cough that does not go away. Pinpoint red spots on your skin. Very bad belly pain. Very upset stomach or throwing up. Very loose stools (diarrhea). Not able to eat. Any bruising or bleeding. Dark urine or yellow skin or eyes. Feeling very tired or weak. For women, if you get pregnant while taking this drug. Any rash. Side effect or health problem is not better or you are feeling worse.

      Can I take Methotrexate with other medicines:

      Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.

      Are there any food restrictions

      Avoid Alcohol

      How do I store Methotrexate :

      Store in a cool, dry place away from the reach of children. - Medicines must not be used past the expiry date.

      Pregnancy Category

      Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

      Therapeutic Classification

      Disease-Modifying Anti-Rheumatic Drugs (DMARDs), Cytotoxic Chemotherapy


      Frequently Asked Questions

      Frequently Asked Questions
      Q1. What is the use of the Folitrax 20MG 1ML injection?

      The injection is used to treat life-threatening conditions like severe rheumatoid arthritis (an autoimmune disease that affects the smaller joints in the body characterized by loss of joint function, progressive bone destruction and damage) and psoriatic arthritis, a form of arthritis associated with psoriasis (characterized by red inflamed skin, often covered by scales) and certain types of cancers that occur in the woman’s uterus. This medicine slows down the progression of the disease and provides relief from pain, swelling and redness.

      Q2. What are the side effects of the Folitrax 20MG 1ML injection?

      This injection is well tolerated when taken in prescribed dosage guidelines. Most common side effects include injection site reactions (swelling, redness, pain), nausea or vomiting, abdominal pain, mouth sores, diarrhoea, indigestion, loss of appetite, joint pain, dizziness, unusual bleeding, blurred vision, pale skin, fever or chills.

      Q3. Should we take Folitrax 20MG 1ML injection with food or without food?

      This injection can be taken with or without food.

      Q4. What are the precautions to be followed while taking the Folitrax 20MG 1ML injection?

      If you ever had impaired kidney function, severe liver impairment or heart disease, let your doctor know before taking this medicine. Inform your doctor about all the medicines you take to ensure that you are healthy. This medicine is contraindicated in patients with hypersensitivity to any of the ingredients used in the injection, pre-existing blood disorders, active gastrointestinal ulcer disease, alcoholism, compromised immune function, severe renal or hepatic impairment, pregnancy and lactation. Caution is advised among patients with concurrent vaccination with live vaccines, folic acid deficiency, bone marrow suppression, dehydrated or debilitated patients, children and elderly.

      Q5. Does Folitrax 20MG 1ML injection make you sleepy?

      This injection may decrease alertness, cause impaired judgement, affect your vision and make you feel dizzy. If you notice any abnormal reactions after taking the medicine do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

      Q6. Is Folitrax 20MG 1ML injection harmful? What does an overdose of Folitrax 20MG 1ML injection lead to?

      The injection is usually well tolerated when taken in the recommended dosage guidelines. Over dose of the medicine may lead to blood disorders, gastrointestinal reactions (ulcer and bleeding, mucositis), headache, increased intracranial pressure, renal failure, aplastic anaemia.

      Q7. Can I take Folitrax 20MG 1ML injection during pregnancy?

      This medicine is not recommended for use during pregnancy as it is known to cause harm to the fetus. Please consult your doctor before consuming this medicine.

      Q8. Can Folitrax 20MG 1ML injection be taken without a doctor’s prescription?

      No, do not take the medicine without doctor’s prescription.

      Q9. Is it okay to drink alcohol while I am on the Folitrax 20MG 1ML injection?

      Consumption of alcohol with this injection is not recommended as it increases the risk of liver damage. If you notice any unusual or abnormal reactions after taking the medicine, report to your doctor immediately.

      Q10. How to store Folitrax 20MG 1ML injection?

      Store the medicine at room temperature (20-30 degree Celsius) in a cool and dry place. Keep the injection according to the instructions mentioned on the pack or label. Store the medicine in the container or the pack it came in, tightly closed.

      Q12. Can we give Folitrax 20MG 1ML injection to children?

      The safety and efficacy of using this medicine in children has not been clinically established.

      Q13. By when should I start seeing the results of the Folitrax 20MG 1ML injection?

      The duration required for the injection to show its effect in the body is within 30-60 minutes of administration.

      Q14. How long does the effect of Folitrax 20MG 1ML injection last?

      The duration for which this medicine remains active in the body is clinically not established.

      Q15. Can we take Folitrax 20MG 1ML injection daily?

      Medicines should always be taken under medical supervision. Take the medicine exactly as prescribed by your doctor: for dosage and duration.

      Q16. For how many days should I take the Folitrax 20MG 1ML injection?

      The number of days that any medicine must be taken varies from patient to patient; and case to case. So always stick to your doctor’s suggestion about how many days to take this medicine.

      Q17. When should I take Folitrax 20MG 1ML injection?

      Use the medicine exactly as prescribed by your doctor for the dosage and duration.

      Note: All of the above information is for reference purpose only. It is always recommended that you consult a medical professional.

      Seller Information
      Manufactured By

      IPCA LABORATORIES LTD

      unit 2,393,melli jorethang road,gom block,bharikhola,south district,sikkim 737121

      Packed By

      IPCA LABORATORIES LTD

      unit 2,393,melli jorethang road,gom block,bharikhola,south district,sikkim 737121

      Applicable Offers

      • 20% Discount
        On prescription medicines, orders above Rs 1000 T & C

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