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FRAGMIN 2500IU INJ

Country of origin: INDIA

1 Units/pack

MRP 427.25

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FLAT 18% OFF On bills above 1000.0
FRAGMIN 2500IU INJ

Fragmin 2500IU injection
Uses and Benefits
Uses and Benefits

Fragmin 2500IU injection is an anticoagulant which is used to prevent and treat blood clots. It prevents the existing clots from becoming larger and inhibits the formation of new clots. It is prescribed in deep vein thrombosis (blood clot formation in legs), pulmonary embolism (blood clot in lung), prophylaxis for myocardial infarction (prevent clot formation in vessels that supply blood to heart), stroke and in prevention of thromboembolism in atrial fibrillation (irregular heartbeat) as well as prophylaxis of ischemic complications in unstable angina. It is a perfect blood thinner and keeps the blood flowing smoothly. This medicine is used in combination with aspirin to prevent serious complications associated with angina and heart attacks. However, the uses of this injection mentioned here are not comprehensive, there may be other conditions for which the medication may be used upon your doctor’s discretion.

Composition

Composition

The active ingredient of Fragmin 2500IU injection is Dalteparin sodium 2500IU

Mechanism of Action of Drugs

Mechanism of Action of Drugs

Dalteparin sodium is a low molecular weight heparin with anticoagulant properties. It works by inactivating blood clotting proteins such as thrombin, thereby preventing the formation of blood clots and prevents blockages in the blood vessels of the body.

Contraindications and Cautions

Contraindications and Caution

Patients with following conditions are suggested to seek advice from their healthcare professionals before using Fragmin 2500IU injection:

  • Hypersensitivity to any of the components used in the injection
  • Central nervous system bleeding
  • Regional anaesthesia
  • Epidural or spinal anaesthesia
  • Haemostatic impairment
  • Severe renal impairment
  • Caution:
  • Haemorrhagic stroke
  • Active bleeding disorder
  • Uncontrolled hypertension
  • History of thrombosis
  • Diabetic retinopathy
  • Surgeries
  • Hepatic and moderate renal impairment
  • Children and elderly
  • Pregnancy and lactation
Side Effects

Side and Adverse Effects

Fragmin 2500IU injection is usually well tolerated when taken in the prescribed dosage guidelines. Most of the side effects are generally mild and you may experience one or more of the following symptoms:

  • Injection site reactions (pain, redness, swelling)
  • Haemorrhage at injection site
  • Peripheral or unspecified oedema
  • Dark red spots in the mouth
  • Bleeding gums
  • Increased menstrual flow
  • Haematuria
  • Black or tarry stools
  • Dyspnoea

Rare but more serious adverse effects may include:

  • Bloody or coffee colored vomit
  • Increased liver enzymes
  • Fast heartbeat
  • Back pain
  • Fever
How to Use

How to Use

Do not self-administer Fragmin 2500IU injection, your nurse or trained physician will give you the medicine. Follow all the instructions given by your doctor carefully. Continue to take the medicine till the time you see an improvement in your health conditions or as advised by your doctor. If a dose is missing, it should be taken as soon as possible.
The injection can be taken with or without food.
Do not change the dose or stop taking the medicine before completion of the course or without consulting your doctor. Continue to use this drug until completion of the maximum amount suggested even though the symptoms disappear after the medicine has begun.

Overdosage

Avoid taking Fragmin 2500IU injection more than the prescribed dosage. Since this injection will be given by doctor or nurse, therefore it is less likely that you will receive overdose of the medicine. If there should be an occurrence of unplanned excess, look for any new signs or symptoms. Overdose of the medicine leads to haemorrhagic complications.

Warnings and Precautions

Warnings and Precautions

Use Fragmin 2500IU injection on the advice of medical practitioner. Complete avoidance of the medication may be required in the following conditions:

Kidney:

Caution is advised among patients with severe renal impairment. Dose adjustments of the injection may be needed. Regular monitoring of kidney function tests is recommended while taking this injection. If you have any renal problems, it is highly recommended that you consult your doctor before taking this medicine.

Liver:

The injection should be used with caution in patients with moderate and severe liver disease. We highly recommend that you consult your doctor before the use. Inform your doctor if you develop signs of jaundice like yellowing of skin and eyes, itching and clay-colored stools while taking this injection.

Pregnancy:

This injection is not considered safe to use in pregnant women unless the potential benefits outweigh the risks involved. Despite the fact that there are limited studies in human beings, animal studies have shown no or low effects on the developing baby. It is recommended that you consult your doctor before taking this injection.

Lactation:

This medication is passed to infants through mother’s milk. Breastfed infants should be closely monitored. Since limited information is available about the safety of taking this injection, consult your doctor if you are nursing mother and stay on the safe side.

Alcohol:

Interaction of alcohol with this injection is unknown. Any symptoms of abnormal reactions after taking the medicine should be reported to your doctor immediately.

Driving:

The medicine does not cause drowsiness or dizziness. If you notice any abnormal reactions after taking the medicine do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

Food:

There are no known food interactions with this injection.

Drug Interactions:

All medicines interact differently for person to person. Inform your doctor or pharmacist if you are taking any other medicines which includes over-the-counter drugs, herbal tonics, supplements and medicines that you buy without a prescription. Alert your doctor if you’re taking Fragmin 2500IU injection along with clopidogrel, escitalopram, fluoxetine, mifepristone, aspirin, streptokinase, ginseng, dextran, rifampicin, warfarin, gentamycin, choline salicylate, vitamin E, heparin topical, diclofenac, alteplase, cyclosporine.

Precautions
  • Do not use this injection post the expiry date
  • Do not use the injection for durations shorter or longer than suggested by your doctor
  • Store at cool temperature (2-8 degree Celsius), do not freeze
FDA Pregnancy Category

FDA Pregnancy Category

Category B: Animal reproduction studies have failed to demonstrate a risk to fetus and there are no adequate and well-controlled studies in pregnant women.


Drug Composition information
What is Dalteparin Sodium for:

This medication is an anticoagulant (blood thinner) that prevents blood clots in persons undergoing surgery. Along with aspirin this medication is prescribed for heart attack, unstable angina (chest pain). It is also used to reduce the recurrence of blood clots in certain cancer patients and during dialysis.

How does Dalteparin Sodium work:

Dalteparin changes the bodys clotting system. It thins the blood to stop clots from forming.

How should Dalteparin Sodium be used:

Use as you have been told, even if you are feeling better. To gain the most benefit, do not miss doses. It is given as a shot into the fatty part of the skin on the right or left side of the stomach, thigh, or buttocks. It is given as a shot into the fatty part of the skin. Your doctor may teach you how to give the shot. Wash your hands before and after use. Move the site where you give the shot with each shot. Throw away needles in a needlesharp disposal box and take the box back to your doctor when it is full.

Common side effects of Dalteparin Sodium :

Irritation where the shot is given. Bleeding problems.

What do I do if I miss a dose

Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.

What precautions should I take when taking Dalteparin Sodium :

Alert your doctor if you are allergic to heparin, other medicines similar to Dalteparin, or pork products. - Alert your doctor if you have or ever had any of these conditions: - bleeding disorders or problems with blood clotting. - stomach ulcers. - stroke or bleeding in the brain. - high blood pressure. - bacterial infection in your heart. - history of low platelet count during treatment with heparin or other medicines similar to Dalteparin. If you are going for a procedure where spinal or epidural anaesthesia is injected into your back, inform your doctor that you are using Dalteparin.

When do I need to seek medical help

If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Very bad dizziness or passing out. A fall or crash when you hit your head. Talk with your doctor even if you feel fine. Swelling, warmth, or pain in the leg or arm. Change in thinking clearly and with logic. Very bad headache. Weakness, numbness, or tingling. Any bruising or bleeding. Any rash. Side effect or health problem is not better or you are feeling worse.

Can I take Dalteparin Sodium with other medicines:

Alert your doctor if you are taking any other medicines, especially those listed here: - other blood-thinning medicines such as warfarin, ticlopidine, clopidogrel, dipyridamole. - painkillers known as NSAIDs, such as aspirin, diclofenac, mefenamic acid, ibuprofen. - certain high blood pressure medicines. - digoxin (a heart medicine). Always inform your doctor and pharmacist if you are taking any other medicines, including herbal tonics, supplements and medicines that you buy without a prescription.

Are there any food restrictions

Avoid Alcohol

How do I store Dalteparin Sodium :

Injection: Store below 25°C. Store it in airtight container and keep away from children.

Pregnancy Category

Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Therapeutic Classification

Anticoagulants and Antiplatelets


Frequently Asked Questions

Frequently Asked Questions
Q1. What is the use of the Fragmin 2500IU injection?

It is an anticoagulant which is used to prevent and treat blood clots. It prevents the existing clots from becoming larger and inhibits the formation of new clots. It is prescribed in deep vein thrombosis (blood clot formation in legs), pulmonary embolism (blood clot in lung), prophylaxis for myocardial infarction (prevent clot formation in vessels that supply blood to heart), stroke and in prevention of thromboembolism in atrial fibrillation (irregular heartbeat) as well as prophylaxis of ischemic complications in unstable angina. It is a perfect blood thinner and keeps the blood flowing smoothly. This medicine is used in combination with aspirin to prevent serious complications associated with angina and heart attacks.

Q2. What are the side effects of the Fragmin 2500IU injection?

The injection is well tolerated when taken in prescribed dosage guidelines. Most common side effects include injection site reactions (pain, redness, swelling), haemorrhage at injection site, peripheral or unspecified oedema, dark red spots in the mouth, bleeding gums, increased menstrual flow, haematuria, black or tarry stools, dyspnoea. Its use may also lead to uncommon side effects such as bloody or coffee colored vomit, increased liver enzymes, fast heartbeat, back pain, fever.

Q3. Should we take Fragmin 2500IU injection with food or without food?

The injection can be taken with or without food.

Q4. What are the precautions to be followed while taking the Fragmin 2500IU injection?

Tell your doctor if you have an allergy to any ingredients used in the injection. Inform your doctor about all the medicines you take to ensure that you are healthy. This medicine is contraindicated in patients with hypersensitivity to any of the components used in the injection, central nervous system bleeding, regional anaesthesia, epidural or spinal anaesthesia, haemostatic impairment. Caution is advised among patients with haemorrhagic stroke, active bleeding disorder, uncontrolled hypertension, history of thrombosis, diabetic retinopathy, surgeries, hepatic and moderate renal impairment, children and elderly, pregnancy and lactation.

Q5. Does Fragmin 2500IU injection make you sleepy?

The medicine does not cause drowsiness or dizziness. If you notice any abnormal reactions after taking the medicine do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

Q6. Is Fragmin 2500IU injection harmful? What does an overdose of Fragmin 2500IU injection lead to?

The injection is usually well tolerated when taken in the recommended dosage guidelines. Since this injection will be given by doctor or nurse, therefore it is less likely that you will receive overdose of the medicine. If there should be an occurrence of unplanned excess, look for any new signs or symptoms. Overdose of the medicine leads to haemorrhagic complications.

Q7. Can I take Fragmin 2500IU injection during pregnancy?

This injection is not considered safe to use in pregnant women unless the potential benefits outweigh the risks involved. Despite the fact that there are limited studies in human beings, animal studies have shown no or low effects on the developing baby. It is recommended that you consult your doctor before taking this injection.

Q8. Can Fragmin 2500IU injection be taken without a doctor’s prescription?

No, do not take the medicine without doctor’s prescription.

Q9. Is it okay to drink alcohol while I am on the Fragmin 2500IU injection?

Interaction of alcohol with this injection is unknown. Any symptoms of abnormal reactions after taking the medicine should be reported to your doctor immediately.

Q10. How to store Fragmin 2500IU injection?

Store the medicine at room temperature (2-8 degree Celsius) in a cool and dry place. Do not freeze. Keep the injection according to the instructions mentioned on the pack or label. Store the medicine in the container or the pack it came in, tightly closed.

Q12. Can we give Fragmin 2500IU injection to children?

The safety and efficacy of using this medicine in children has not been clinically established.

Q13. By when should I start seeing the results of the Fragmin 2500IU injection?

The amount of time required for this medicine to show its action is within 1-2 hours of administration.

Q14. How long does the effect of Fragmin 2500IU injection last?

The amount of time for which this medicine remains active in the body is for about 12 hours.

Q15. Can we take Fragmin 2500IU injection daily?

Medicines should always be taken under medical supervision. Take the medicine exactly as prescribed by your doctor: for dosage and duration.

Q16. For how many days should I take the Fragmin 2500IU injection?

The number of days that any medicine must be taken varies from patient to patient; and case to case. So always stick to your doctor’s suggestion about how many days to take this medicine.

Q17. When should I take Fragmin 2500IU injection?

Use the medicine exactly as prescribed by your doctor for the dosage and duration.

Note: All of the above information is for reference purpose only. It is always recommended that you consult a medical professional.

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