This medication is a synthetic vitamin D analog, prescribed for hypocalcemia in patients undergoing chronic renal dialysis. It helps proper absorption and use of calcium and phosphate in the body.
It works by helping the body to use more of the calcium found in foods and supplements.
PO- The recommended initial dose is 1 mcg (0.02 mcgkg) to 2 mcg administered three times weekly, approximately every other day. It comes as a tablet and capsule to take by mouth, with or without food.
Dry mouth, muscle pain, increased thirst, loss of appetite, vomiting, metallic taste, upset stomach, constipation, difficult urination.
Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.
Tell your doctor if you are allergic to any drugs. Some drugs like phenytoin, phenobarbital, prednisone and some laxatives may affect the availability. Inform your doctor if you have kidney or liver disease, pregnant, or planning to have surgery including dental procedures.
Seek help if you have signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Inform doctor if you experience any bruising or bleeding, any rash, or if any side effect or health problem is not better or you are feeling worse.
This drug will only work if you get the right amount of calcium from your diet. If you are being treated with dialysis, your doctor may also prescribe a low phosphate diet. Follow these directions carefully. If you do not have kidney disease, you should drink plenty of fluids when taking this drug. If you have kidney disease, talk to your doctor about how much fluid you should drink each day.
Avoid alcohol and grapefruit juice.
Store the medication at 25°C (77°F); excursions permitted to 15° to 30°C (59° to 86°F).
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Agents Affecting Bone Metabolism, Vitamins
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