Glucotrol MF tablet is a combination anti-diabetic medication used to treat type 2 diabetes mellitus. This medicine is used with a proper healthy diet and exercise program to control high blood sugar in people with type 2 diabetes. Controlling high blood sugar level helps in preventing kidney damage, blindness, nerve problems and loss of limbs. However, the uses of the tablet mentioned here are not exhaustive. There may be other conditions for which this medication may be used upon doctor’s discretion.
The active ingredients of Glucotrol MF tablet are Glipizide (5Mg) and Metformin (500Mg)
Glipizide works by increasing the release of insulin from the pancreas and decreasing the hormones (glucagon) that raise blood glucose levels thereby reducing the fasting and post-meal sugar levels. Metformin reduces hepatic glucose production, decreases intestinal absorption of glucose and improves insulin sensitivity by increasing peripheral glucose uptake and utilization. The combination is thus better effective in lowering blood glucose levels.
Patients with the following conditions are suggested to seek advice from their health care professionals before taking the Glucotrol MF tablet:
Glucotrol MF is usually well tolerated when used in the prescribed dosage guidelines. Most side effects are temporary and usually subsides on their own. However, consult your doctor if they persist for a longer duration. You may experience one or more of the following symptoms:
Rare but more serious adverse effects may include:
Take Glucotrol MF tablet as instructed by your doctor. Swallow the tablet whole with water, immediately after opening it from the strip. Do not break or crush or chew the tablet.
Avoid missing or forgetting the dose. If you do, take it as soon as you remember; but if it’s almost time for your next dose, skip it and take it according to your normal schedule. Don’t swallow two doses at the same time which is dangerous to your health.
The tablet should be taken with food, immediately or during breakfast or the first main meal of the day. Take the tablet at the same time every day as it helps to maintain a consistent level of medicine in the body.
Do not change the dose or stop taking the medicine before completion of the course or without consulting your doctor. Continue to use this drug until completion of the maximum amount suggested even though the symptoms disappear after the medicine has begun. This medicine is not recommended for children below 18 years of age.
Avoid taking Glucotrol MF tablet more than the prescribed dosage. In case of an accidental overdose of the medicine, promptly ask for medical advice. Depending on the dosage of the medicine, symptoms may vary in individuals, you may experience the following signs or symptoms:
Take the tablet only on the advice of a medical practitioner. Dosage adjustment or complete avoidance of the Glucotrol MF tablet may be required in the following conditions:
Among people with renal problems, caution is recommended. Close monitoring of kidney function and adjustments of dose of the medicine may be needed based on the clinical condition of the patient. If you have any, it is highly recommended that you consult your doctor before the consumption of this medicine.
Caution is advised among people with liver problems. Dose adjustments of the tablet may be needed based on the clinical condition of the patient. If you have any hepatic problems, it is highly recommended that you consult doctor before the consumption of this medicine. However, use of this tablet is not suggested in patients with severe liver diseases.
It is not considered safe to use in pregnant women unless the potential benefits outweigh the risks involved. Despite the fact that there are limited studies in human beings, animal studies have shown adverse effects on the developing baby. It is recommended that you consult your doctor before consuming this medicine.
There is no information regarding the presence of this medicine in human milk, or the breastfed infant, or the effects on milk production. However, inform your doctor if you are a nursing mother as it is still unknown if it causes harm to the foetus or not.
Consumption of alcohol with this tablet is not recommended as it increases side effects of the tablet. If found any symptoms of extreme drowsiness, vomiting, confusion, report to your doctor immediately.
This medicine affects blood glucose levels and may decrease alertness, cause impaired judgement, affect your vision and make you feel dizzy. Do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.
There are no known food interactions with this tablet.
Inform your doctor or pharmacist if you are taking any other medicines which includes over-the-counter drugs, herbal tonics, supplements and medicines that you buy without a prescription. Alert your doctor if you are taking Glucotrol MF tablet along with ACE inhibitors, sulfonylurea, dichlorphenamide, NSAIDs, cimetidine, trimethoprim, acetazolamide, insulin, thiazides, iodinated contrast media, gatifloxacin, furosemide.
Category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
This medication is a sulfonylurea antidiabetic agent, prescribed for type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood), particularly in people whose diabetes cannot be controlled by diet alone.
It increases the amount of insulin secretion and thus regulates the sugar level in the blood.
Take as you have been told, even if you are feeling better. This drug may be used alone or with other high blood sugar (diabetes) drugs. Follow the diet and workout plan that your doctor told you about. Fast release: - Take 30 minutes before the first meal of the day. Long-acting products: - Take with the first meal of the day. Swallow whole. Do not chew, break, or crush.
Long-acting tablet shell in the stool. Low blood sugar. Signs include anger, shaking, a fast heartbeat, confusion, or sweating. Keep hard candies, glucose tablets, liquid glucose, or juice on hand for low blood sugar. Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. Weight gain.
Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.
If you have an allergy to glipizide or any other part of this drug. Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you have a sulfa (sulfonamide) allergy, talk with your doctor. Long-acting products: If you have a narrowing of the GI (gastrointestinal) tract or a bowel block. If you have any of these health problems: Acidic blood problem or type 1 diabetes. If you are breast-feeding.
If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Signs of infection. These include a fever of 100.5°F (38°C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain. Very upset stomach or throwing up. Very low blood sugar or very high blood sugar. Very bad belly pain. Dark urine or yellow skin or eyes. Not able to eat. Any rash. Side effect or health problem is not better or you are feeling worse.
Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.
Store in a cool, dry place away from the reach of children. - Medicines must not be used past the expiry date.
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
The tablet is a combination anti-diabetic medication used to treat type 2 diabetes mellitus. This medicine is used with a proper healthy diet and exercise program to control high blood sugar in people with type 2 diabetes. Controlling high blood sugar level helps in preventing kidney damage, blindness, nerve problems.
The medicine is well tolerated when taken in prescribed dosage guidelines. Common side effects such as blurred vision, confusion, chills, anxiety, depression, fast heartbeat, fever, headache, nervousness, nausea, sore throat, unusual weakness and tiredness, increased hunger. Its use may also lead to extreme but uncommon side effects such as lactic acidosis, nasopharyngitis, upper respiratory tract infection, swelling of face, lips, eyelids, tongue, hands and feet, acute pancreatitis.
The tablet should be taken with food, immediately or during breakfast or the first main meal of the day.
If you ever had kidney, liver or heart disease, let your doctor know before taking this medicine. Inform your doctor about all the medicines you take to ensure that you are healthy. This medicine is contraindicated in patients with hypersensitivity to any of the active ingredients used in tablet, severe renal impairment, acute alcohol intoxication, hepatic impairment, acute or chronic metabolic acidosis, type 1 diabetes, diabetic ketoacidosis. Caution is advised among patients with lactic acidosis, stable heart failure, dehydration, prerenal azotaemia, children and elderly, pregnancy and lactation.
The tablet affects blood glucose levels and may decrease alertness, cause impaired judgement, affect your vision and make you feel dizzy. Do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.
The tablet is usually well tolerated when taken in the recommended dosage guidelines. Over dose of the medicine may lead to hypoglycaemia, lactic acidosis, muscle cramps, hypothermia, cholestatic liver injury.
It is not considered safe to use in pregnant women unless the potential benefits outweigh the risks involved. Despite the fact that there are limited studies in human beings, animal studies have shown no or low adverse effects on the developing baby. It is recommended that you consult your doctor before consuming this medicine.
No, do not take this medicine without doctor’s prescription.
Consumption of alcohol with this medicine is not recommended as it increases side effects of the tablet. If found any symptoms of extreme drowsiness, vomiting, confusion, report to your doctor immediately.
Store the medicine at room temperature (20-30 degree Celsius) in a cool and dry place. Keep the tablet according to the instructions mentioned on the pack or label. Store the medicine in the container or the pack it came in, tightly closed.
This tablet is designed to be swallowed with water. If you take them in a way they weren’t intended to be used, you could experience an overdose if the active constituent enters the blood stream too quickly. Alternatively, if it enters your body too slowly, it may never achieve a high enough concentration to be completely functional.
This medicine is not recommended for children below 18 years of age as the safety and efficacy of the tablet is not clinically established.
The amount of time required for this medicine to show its effect in the body is within 30-45 minutes of administration.
The amount of time for which this medicine remains active in the body is for about 12-24 hours.
Medicines should always be taken under medical supervision. Take the medicine exactly as prescribed by your doctor: for dosage and duration. Most recommended dose is one tablet a day.
The number of days that any medicine must be taken varies from patient to patient; and case to case. It is important to keep your blood glucose levels under control as any fluctuations in your blood glucose levels may cause serious problems. So always stick to your doctor’s suggestion about how many days to take this medicine.
Use the medicine exactly as prescribed by your doctor for the dosage and duration.
Note: All of the above information is for reference purpose only. It is always recommended that you consult a medical professional.
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nirmala apartments, 93, jp rd, azad nagar, andheri west, mumbai, maharashtra 400058
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