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      IMPECT 12MG TAB

      Impect 12mg tab
      Uses and Benefits

      Uses and Benefits

      Impect 12mg tablet contains Ivermectin which belongs to class of anti-helminthic medicines. This tablet is used to treat parasitic infections of your intestinal tract, skin and eyes. It is used in the treatment of strongyloidiasis, onchocerciasis and scabies in patients who don’t respond to topical medications. However, uses of the tablet mentioned here are not comprehensive, there may be other conditions for which the tablet may be used upon your doctor’s discretion.

      Composition

      Composition

      The active ingredient of Impect 12mg tablet is Ivermectin 12mg.

      Mechanism of Action of Drugs

      Mechanism of Action of Drugs

      Ivermectin binds act by interfering with nerve and muscle function of helminths and insects. The drug binds to channels of glutamate-gated chloride that are common to invertebrate nerve and muscle cells. The binding of Ivermectin pushes these channels open, increasing the flow of chloride ions and hyper polarising the cell membranes. The affected tissue is paralysed by this hyper-polarisation, ultimately killing the invertebrate.

      Contraindications and Cautions

      Contraindications and Caution

      Patients with following conditions are suggested to seek advice from their healthcare professionals before taking Impect tablet.

      • Hypersensitivity to any of the constituents used in the tablet formulation.
      • Immunocompromised patients
      • Caution:
      • Patients with onchocerciasis and loiasis
      • Asthma patients
      • People with seizures
      • People with HIV
      Side Effects

      Side and Adverse Effects

      The following side effects may occur during the usage of this tablet. Impect 12mg is usually well tolerated when taken in the prescribed dosage guidelines. More common ones include:

      • Lymphadenitis
      • Headache
      • Somnolence
      • Vomiting
      • Metallic taste
      • Vertigo
      • Nausea
      • Constipation
      • Stomach upset

      Rare but more serious adverse effects may include:

      • Encephalopathy
      • Dizziness
      • Loss of consciousness
      • Anorexia
      • Conjunctival haemorrhage
      • Tachycardia
      • Orthostatic hypotension
      How to Use

      How to Use

      Don’t exceed the tablet dose prescribed by your health care physician. Take Impect tablet soon after opening it from the strip. Don’t break/chew the tablet.
      Avoid missing or forgetting the dose. If you do, take it as early as you remember, but if it’s almost time for your next dose, skip it and take it according to your next scheduled dose. Don’t swallow two doses at the same time. Don’t change the dose or stop the drug.
      Take the tablet on an empty stomach with a glass full of water.

      Overdosage

      Try avoid taking more than the recommended dosage. In case of overdose, promptly ask for medical advice. Depending on the dosage of Impect tablet, symptoms may vary in individuals, you may experience one or more of the following symptoms:

      • Inability to control urination
      • Trouble standing or walking
      • Shortness of breadth
      • Inability to control bowel movements
      • Extreme drowsiness
      Warnings and Precautions

      Warnings and Precautions

      Dosage adjustments or complete avoidance of the Impect tablet may be required in the following conditions:

      Kidney:

      This tablet should be used with caution in patients with renal problems as it might lower blood sugar levels. If you have any renal problems, it is highly recommended that you consult your doctor before the consumption of this medicine.

      Liver:

      Impect Tablet should be used with caution in patients with moderate and severe liver disease. If you have any hepatic problems, we recommend you consult your doctor before the consumption of this medicine.

      Pregnancy:

      Use of Ivermectin is not advised for pregnant women unless the clinical condition of the patient requires treatment. We highly recommend you to consult your doctor before the consumption of this medicine.

      Lactation:

      Use of Impect tablet is not advised for nursing mothers unless the clinical condition of the patient requires treatment. We highly recommend that you consult your doctor before the consumption of this medicine.

      Alcohol:

      Do not take this medicine along with alcohol beverages as it may increase concentration of the medicine and this may cause severe adverse effects such as dizziness, vomiting, diarrhea, abdominal pain, skin rash, etc.

      Driving:

      Impect tablet may decrease alertness, affect your vision and make you feel dizzy. Do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

      Food:

      High fat meal has been shown to increase the bioavailability of Impect 12mg tablet.

      Drug Interactions:

      Barbiturates (Phenobarbital, Butalbital).
      Benzodiazepines (Clonazepam, Lorazepam)
      Sodium oxybate
      Valproic acid
      Digoxin (Lanoxin)
      Warfarin
      Diethylcarbamazine
      Always inform your doctor or pharmacist if you are taking any other medicines which includes herbal tonics, medicines and supplements that you buy without a prescription.

      Precautions
      • Do not use this medicine post the expiry date
      • Store at room temperature below 88-degree Fahrenheit
      • Keep the tablet out of reach of children
      FDA Pregnancy Category

      FDA Pregnancy Category

      Category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


      Drug Composition information
      What is Ivermectin for:

      This medication is an anthelmintic, prescribed for certain parasitic roundworm infections such as Strongyloidiasis and Onchocerciasis.

      How does Ivermectin work:

      It kills the worms in the intestines.

      How should Ivermectin be used:

      It comes as a tablet to take by mouth, as single dose on an empty stomach with a full glass of water.

      Common side effects of Ivermectin :

      Loose stools (diarrhea). Itching. Joint pain. Skin irritation.

      What do I do if I miss a dose

      Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses.

      What precautions should I take when taking Ivermectin :

      If you have an allergy to ivermectin or any other part of this drug. Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you are pregnant or may be pregnant. If you are breast-feeding.

      When do I need to seek medical help

      If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Signs of infection. These include a fever of 100.5°F (38°C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain. A fast heartbeat. Sudden change in eyesight, eye pain, or irritation. Very bad skin irritation. Very loose stools (diarrhea). Any rash. Side effect or health problem is not better or you are feeling worse.

      Can I take Ivermectin with other medicines:

      Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.

      Are there any food restrictions

      Avoid Alcohol

      How do I store Ivermectin :

      Store in a cool, dry place away from the reach of children. - Medicines must not be used past the expiry date.

      Pregnancy Category

      Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

      Therapeutic Classification

      Antihelmintics

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