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      Country of origin: INDIA

      Seller Information

      8 Units/pack

      MRP 207

      Inclusive of all Taxes

      FLAT 20% OFF On bills above 1000.0
      IT MAC 200MG CAP

      IT Mac 200MG capsule
      Uses and Benefits

      Uses and Benefits

      IT Mac 200MG capsule is an anti-fungal medicine used to treat infections caused by fungi and certain yeasts. It is prescribed for oropharyngeal candidiasis (fungal infection in the mouth), oesophageal candidiasis (infection of oesophagus or food pipe causing painful swallowing), blastomycosis (infection that affects your lungs and also other parts of the body such as skin, bones and joints), vaginal candidiasis (infection causing pain, itching and burning sensation with unusual discharge in the genital organs), onychomycosis (fungal infection in the finger nail and toe nail), peritonitis (fungal infection causing inflammation of thin layer of tissue that covers the inside of abdomen and most organs present in the abdomen), candidemia (a condition in which the fungus enters blood stream and from the blood to eyes, liver, brain causing invasive candidemia). This medicine acts by stopping the growth and multiplication of these organisms. However, the uses mentioned here are not comprehensive, there may be other conditions for which the medication may be used upon your doctor’s discretion.

      Composition

      Composition

      The active ingredient of AF capsule is Itraconazole 200MG

      Mechanism of Action of Drugs

      Mechanism of Action of Drugs

      Itraconazole changes the permeability of the cell wall of the fungal cells and prevents their growth. It binds to the phospholipids of the membrane and inhibits the fungal CYP450 activity, thereby decreasing ergosterol biosynthesis that are essential for the development of the cell membrane. This results in the death of cells due to the loss of intracellular sections.

      Contraindications and Cautions

      Contraindications and Caution

      Patients with following conditions are suggested to seek advice from their healthcare professionals before using IT Mac 200MG capsule:

      • Hypersensitivity to any of the ingredients used in the capsule and other antifungals
      • Congestive heart failure
      • Severe renal impairment
      • Concomitant use with QT interval prolonging drugs
      • Caution:
      • Ischaemic or valvular disease
      • Reduced gastric acidity
      • Cystic fibrosis
      • Hepatic impairment
      • Weak immune system
      • Children and elderly
      • Pregnancy and lactation
      Side Effects

      Side and Adverse Effects

      IT Mac 200MG capsule is usually well tolerated when used in the prescribed dosage guidelines. Most side effects are temporary and usually subsides on their own. However, consult your doctor if they persist for a longer duration. You may experience one or more of the following symptoms:

      • Common cold
      • Cough
      • Menstrual disorder
      • Blurred vision
      • Headache
      • Dizziness
      • Drowsiness
      • Tiredness
      • Increased blood pressure
      • Nausea, vomiting
      • Stomach pain
      • Diarrhea
      • Constipation
      • Hair loss

      Rare but more serious adverse effects may include:

      • Abnormal liver functions
      • Hypokalaemia
      • Jaundice
      How to Use

      How to Use

      Take IT Mac 200MG capsule as instructed by your doctor. Swallow the capsule whole with water, immediately after opening it from the strip. Do not break or crush or chew the capsule.
      Avoid missing or forgetting the dose. If you do, take it as soon as you remember; but if it’s almost time for your next dose, skip it and take it according to your normal schedule. Don’t swallow two doses at the same time which is dangerous to your health.
      This capsule should be taken with food, immediately after a full meal. Take the capsule at the same time every day as it helps to maintain a consistent level of medicine in the body.
      Do not change the dose or stop taking the medicine before completion of the course or without consulting your doctor. Continue to use this drug until completion of the maximum amount suggested even though the symptoms disappear after the medicine has begun. Stopping the medication too early can allow the growth of the fungus to begin, which can lead to an infection relapse.

      Overdosage

      Avoid taking more than the prescribed dosage. If you notice any unusual or abnormal reactions after taking the capsule, promptly seek medical attention. Depending on the dosage of IT Mac 200MG capsule, symptoms vary in individuals, you may experience one or more of the following symptoms:

      • Short of breath
      • Cough with mucus
      • Fast heartbeats
      • Hypertension
      • Rapid weight gain
      • Sleep problems
      • Acute liver failure
      Warnings and Precautions

      Warnings and Precautions

      Use this capsule on the advice of medical practitioner. Complete avoidance of the AF capsule may be required in the following conditions:

      Kidney:

      Extreme caution is advised among people with kidney problems. Close monitoring of kidney function and adjustments of dose of the medicine may be needed based on the clinical condition of the patient. If you have any renal problems, it is highly recommended that you consult doctor before the consumption of this capsule.

      Liver:

      Caution is advised among people with liver problems. Dose adjustments of the capsule may be needed. If you have any hepatic problems, it is highly recommended that you consult doctor before the consumption of this medicine. Inform your doctor if you develop signs of jaundice like yellowing of skin and eyes, itching and clay-colored stools while taking this capsule.

      Pregnancy:

      This medicine should be used with caution during pregnancy. Despite the fact that there are limited studies in human beings, animal studies have shown harmful effects on the developing baby. It is recommended that you consult your doctor before consuming this medicine.

      Lactation:

      This medicine is not considered safe to use in nursing mothers unless the potential benefits outweigh the risks involved. Since the effect of the medicine on infants is not clearly established, we recommend that you to consult your doctor before consuming the capsule.

      Alcohol:

      Interaction of alcohol with this capsule is unknown. Any symptoms of abnormal reactions after taking the medicine should be reported to your doctor immediately.

      Driving:

      This medicine may decrease alertness, cause impaired judgement, affect your vision and make you feel dizzy. Do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

      Food:

      There are no known food interactions with this medicine.

      Drug Interactions:

      Inform your doctor or pharmacist if you are taking any other medicines which includes over-the-counter drugs, herbal tonics, supplements and medicines that you buy without a prescription. Alert your doctor if you’re taking IT Mac 200MG capsule with anti-psychotic medications (lurasidone, pimozide), cholesterol-lowering medicines (lovastatin, simvastatin), ergot medicines (methylergonovine, ergotamine), alprazolam, carbamazepine, antineoplastic agents (busulfan, vinca alkaloids) immunosuppressants (ciclosporins, tacrolimus), corticosteroids (fluticasone, dexamethasone), oral anticoagulants (coumarins, apixaban). Avoid taking antacids within one hour or two hours after you take the capsule as few antacids can make it harder for your body to absorb the medicine.

      Precautions
      • Do not use this capsule post the expiry date
      • Do not use this medication for durations shorter or longer than suggested by your doctor
      • Store at room temperature (20-30 degree Celsius)
      FDA Pregnancy Category

      FDA Pregnancy Category

      Category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


      Drug Composition information
      What is Itraconazole for:

      This medication is an antifungal agent, prescribed for treating fungal infections.

      How does Itraconazole work:

      It interferes with the formation of the fungal cell membrane and kills fungi.

      How should Itraconazole be used:

      It comes as a capsule to take by mouth, on an empty stomach. Adult- PO- The recommended dose is 100 to 200 mg once daily (2 capsules).

      Common side effects of Itraconazole :

      Headache. Belly pain. Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. Loose stools (diarrhea). Hearing loss. This can be long-lasting. Harm to the liver may rarely happen.

      What do I do if I miss a dose

      Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.

      What precautions should I take when taking Itraconazole :

      If you have an allergy to itraconazole or any other part of this drug. Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you have a weak heart or are pregnant and are being treated for a nail infection. If you had liver problems while taking some other drug in the past.

      When do I need to seek medical help

      If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Trouble breathing. Very bad swelling. Very bad belly pain. Very upset stomach or throwing up. Very loose stools (diarrhea). Change in hearing. Sudden change in eyesight. Numbness or tingling in your hands or feet. Not able to eat. A big weight gain. Swelling on legs or feet. Dark urine or yellow skin or eyes. Feeling very tired or weak. Any rash. Side effect or health problem is not better or you are feeling worse.

      Can I take Itraconazole with other medicines:

      Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.

      Are there any food restrictions

      Avoid Alcohol

      How do I store Itraconazole :

      Store in a cool, dry place away from the reach of children. - Medicines must not be used past the expiry date.

      Pregnancy Category

      Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

      Therapeutic Classification

      Antifungals


      Frequently Asked Questions

      Frequently Asked Questions
      Q1. What is the use of the IT Mac 200MG capsule?

      The capsule is an anti-fungal medicine used to treat infections caused by fungi and certain yeasts. It is prescribed for oropharyngeal candidiasis (fungal infection in the mouth), oesophageal candidiasis (infection of oesophagus or food pipe causing painful swallowing), blastomycosis (infection that affects your lungs and also other parts of the body such as skin, bones and joints), vaginal candidiasis (infection causing pain, itching and burning sensation with unusual discharge in the genital organs), onychomycosis (fungal infection in the finger nail and toe nail), peritonitis (fungal infection causing inflammation of thin layer of tissue that covers the inside of abdomen and most organs present in the abdomen), candidemia (a condition in which the fungus enters blood stream and from the blood to eyes, liver, brain causing invasive candidemia). This medicine acts by stopping the growth and multiplication of these organisms.

      Q2. What are the side effects of the IT Mac 200MG capsule?

      The capsule is well tolerated when taken in prescribed dosage guidelines. Most common side effects include common cold, cough, menstrual disorder, blurred vision, headache, nausea, vomiting, dizziness, drowsiness, tiredness, increased blood pressure, abdominal pain, diarrhea, constipation, hair loss. Its use may also lead to extreme but uncommon side effects such as abnormal liver functions, yellowing of skin or eyes, hypokalaemia, jaundice.

      Q3. Should we take IT Mac 200MG capsule with food or without food?

      The capsule should be taken with food, immediately after a full meal.

      Q4. What are the precautions to be followed while taking the IT Mac 200MG capsule?

      If you ever had impaired kidney function, liver impairment or heart disease, let your doctor know before taking this medicine. Inform your doctor about all the medicines you take to ensure that you are healthy. This medicine is contraindicated in patients with hypersensitivity to ingredients in the capsule and other azoles, congestive heart failure, severe renal impairment, concomitant use with QT interval prolonging drugs. Caution is advised among patients with ischaemic or valvular disease, reduced gastric acidity, cystic fibrosis, hepatic impairment, weak immune system, children, elderly, pregnancy and lactation.

      Q5. Does IT Mac 200MG capsule make you sleepy?

      This medicine may decrease alertness, cause impaired judgement, affect your vision and make you feel dizzy. Do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

      Q6. Is IT Mac 200MG capsule harmful? What does an overdose of IT Mac 200MG capsule lead to?

      The capsule is usually well tolerated when taken in the recommended dosage guidelines. Over dose of the medicine may lead to short of breath, cough with mucus, fast heartbeats, hypertension, rapid weight gain, sleep problems, acute liver failure.

      Q7. Can I take IT Mac 200MG capsule during pregnancy?

      This medicine should be used with caution during pregnancy. Despite the fact that there are limited studies in human beings, animal studies have shown harmful effects on the developing baby. It is recommended that you consult your doctor before consuming this medicine.

      Q8. Can IT Mac 200MG capsule be taken without a doctor’s prescription?

      No, do not take the medicine without doctor’s prescription.

      Q9. Is it okay to drink alcohol while I am on the IT Mac 200MG capsule?

      Interaction of alcohol with this capsule is unknown. Any symptoms of abnormal reactions after taking the medicine should be reported to your doctor immediately.

      Q10. How to store IT Mac 200MG capsule?

      Store the medicine at room temperature (20-30 degree Celsius) in a cool and dry place. Keep the capsule according to the instructions mentioned on the pack or label. Store the medicine in the container or the pack it came in, tightly closed.

      Q11. If I have trouble swallowing IT Mac 200MG capsule, can I mix it in water and drink it?

      This capsule is designed to be swallowed with water. If you take them in a way they weren’t intended to be used, you could experience an overdose if the active constituent enters the blood stream too quickly. Alternatively, if it enters your body too slowly, it may never achieve a high enough concentration to be completely functional.

      Q12. Can we give IT Mac 200MG capsule to children?

      If used according to the directions given by your doctor, it is safe to be used in children.

      Q13. By when should I start seeing the results of the IT Mac 200MG capsule?

      The amount of time required for this medicine to show its action is not clinically determined. You will start to feel better in 2-4 days after taking the capsule.

      Q14. How long does the effect of IT Mac 200MG capsule last?

      The amount of time for which this medicine remains active on the body is not clinically determined.

      Q15. Can we take IT Mac 200MG capsule daily? If yes, how many capsules can we take everyday?

      Medicines should always be taken under medical supervision. Take the medicine exactly as prescribed by your doctor: for dosage and duration. Most recommended dose is one capsule a day.

      Q16. For how many days should I take the IT Mac 200MG capsule?

      The number of days that any medicine must be taken varies from patient to patient; and case to case. So always stick to your doctor’s suggestion about how many days to take this medicine.

      Q17. When should I take IT Mac 200MG capsule?

      Use the medicine exactly as prescribed by your doctor for the dosage and duration.

      Note: All of the above information is for reference purpose only. It is always recommended that you consult a medical professional.

      Seller Information
      Manufactured By

      MACLEODS PHARMACEUTICALS LTD

      khasra no-21,22,66,67&68-aho-yangtam,namchepung,po-ranipool,sikkim-737135 office-macleods pharmaceuticals ltd atlanta arcade,marol church road,andheri (east),mumbai - 400 059, india.

      Packed By

      MACLEODS PHARMACEUTICALS LTD

      khasra no-21,22,66,67&68-aho-yangtam,namchepung,po-ranipool,sikkim-737135 office-macleods pharmaceuticals ltd atlanta arcade,marol church road,andheri (east),mumbai - 400 059, india.

      Applicable Offers

      • 20% Discount
        On prescription medicines, orders above Rs 1000 T & C

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