It is used to stop or control seizures. It is used to stop migraine headaches. It is used to treat manic low mood (depression). It is used to treat problems with how one acts. It is used to help diabetic nerve pain.
Valproic acid and derivatives help clear thinking. It raises a chemical called gamma-aminobutyric in the brain. This chemical calms the brain. It helps steady mood.
Take as you have been told, even if you are feeling better. Take with or without food. Take with food if it causes an upset stomach. Swallow capsule whole. Do not chew, break, or crush. You may sprinkle contents of Depakote® Sprinkle® capsule on soft food or liquid. Do not chew. Take with a full glass of water. There is a liquid (syrup) if you cannot swallow pills. Those who have feeding tubes may also use the liquid. Flush the feeding tube before and after this drug is given. Do not mix with carbonated drinks.
Feeling lightheaded, sleepy, having blurred eyesight, or a change in thinking clearly. Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how this drug affects you. Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing. Headache. Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. Loose stools (diarrhea). Belly pain. Hair loss. Muscle weakness. Twitching. Not able to sleep.
Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses.
If you have an allergy to valproic acid or any other part of this drug. Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you have liver disease. If you are pregnant or may be pregnant. If you are breast-feeding.
If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Signs of low mood (depression), thoughts of killing yourself, nervousness, emotional ups and downs, thinking that is not normal, anxiety, or lack of interest in life. Very upset stomach or throwing up. Very bad belly pain. Not able to eat. Big change in balance. Any bruising or bleeding. Dark urine or yellow skin or eyes. Feeling very tired or weak. If seizures are worse or not the same after starting this drug. For women, if you are pregnant or may be pregnant. Any rash. Side effect or health problem is not better or you are feeling worse.
Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.
Store in a cool, dry place away from the reach of children. - Medicines must not be used past the expiry date.
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Anticonvulsants, Antipsychotics, Antimigraine Preparations
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