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      Country of origin: INDIA

      LIFE PAN DSR CAP

      Life Pan DSR Capsule
      Uses and Benefits

      Uses and Benefits

      Life Pan DSR Capsule is used to treat gastro-oesophageal reflux disease, peptic ulcer, H. Pylori infection, prophylaxis of NSAID induced ulcers, zollinger-ellison syndrome, erosive oesophagitis. It is also used to treat dyspepsia, heartburn, epigastric pain, nausea, and vomiting. However, the uses mentioned here are not exhaustive. There may be other conditions for which this medication may be used upon doctor’s discretion.

      Composition

      Composition

      The active ingredients of Life Pan DSR Capsule are Pantoprazole 40mg and Domperidone 30mg.

      Mechanism of Action of Drugs

      Mechanism of Action of Drugs

      Pantoprazole is a proton pump inhibitor which acts by inhibiting the gastric acid secretion in the stomach.
      Domperidone possesses anti-emetic properties which help reduce vomiting and vomiting sensation; and also treats gastric problems to an extent.

      Contraindications and Cautions

      Contraindications and Caution

      Patients with the following conditions are suggested to seek advice from their health care professional before taking the Life Pan DSR Capsule:

      • Hypersensitivity to any of the ingredients used in the Life Pan DSR Capsule such as Pantoprazole and Domperidone
      • QT prolongation
      • Electrolyte disturbance
      • Cardiac disease
      • GI hemorrhage
      • Hepatic impairment, moderate to severe
      • Caution:
      • Long term use
      • High dose
      • Hypomagnesemia
      • Patients 50 years and older
      Side Effects

      Side and Adverse Effects

      The following side effects may or may not occur due to the consumption of Life Pan DSR Capsule. It is generally well tolerated when taken in the prescribed dosage guidelines. More common ones are generally mild and may include:

      • Headache
      • Diarrhea
      • Thrombophlebitis
      • Abdominal pain
      • Nausea/vomiting
      • URI sx
      • Fever
      • Rash
      • Dizziness
      • Flatulence
      • Arthralgia
      • Vitamin B12 deficiency
      • Fundic gland polyps
      • Dryness of mouth
      • Increased prolactin levels
      • Amenorrhea
      • Gynaecomastia
      • Best pain and tenderness
      • Urticaria
      • Rash
      • Pruritus
      • Transient intestinal cramps
      • Diarrhea
      • Nervousness
      • Anxiety
      • Arrhythmias
      • Bradycardia
      • Tachycardia

      Rare but more serious adverse effects may include:

      • Hypersensitivity reaction
      • Anaphylaxis
      • Erythema multiforme
      • Stevens-johnson syndrome
      • Toxic epidermal necrolysis
      • Interstitial nephritis
      • Renal impairment
      • Pancreatitis
      • Rhabdomyolysis
      • Fractures
      • Hyponatremia
      • Hypomagnesemia
      • Lupus erythematosus
      • C. Difficile associated diarrhea
      • Blood dyscrasias
      • Hepatic impairment
      • Serious ventricular arrhythmia
      • Sudden cardiac death
      • Torsade de pointes
      • Anaphylaxis
      • Angioedema
      How to Use

      How to Use

      Do not exceed the dose prescribed by your doctor. Swallow the Life Pan DSR Capsule immediately after opening it from the strip. Do not break/crush/chew the capsule.

      Avoid missing or forgetting a dose. If you do, take it as soon as you remember; but if it is almost time for your next dose, skip it and take it according to your normal schedule. Do not consume two doses at the same time in order to compensate for the missed dose – this may prove dangerous to your health.
      Life Pan DSR Capsule may be taken either with or without food.
      Take the medicine as recommended by your doctor at the prescribed time and dosage.
      Life Pan DSR Capsule is not recommended in children younger than 5 years.

      Overdosage

      Avoid taking more than the prescribed dosage. In case of an accidental overdose, look for any new or abnormal symptoms. If you find any, promptly seek medical advice. Depending on the dosage, symptoms may vary but you may experience one or more of the following signs or symptoms:

      • Altered consciousness
      • Convulsion
      • Agitation
      • Somnolence
      • Extrapyramidal reactions
      • Disorientation
      Warnings and Precautions

      Warnings and Precautions

      Take Life Pan DSR Capsule only on the advice of a medical practitioner. Dosage adjustment or complete avoidance of the medication may be required in the following conditions:

      Pregnancy:

      Safety is not yet established. Therefore, inform your doctor if you are pregnant or planning to get pregnant during the treatment.

      Lactation:

      Inform your doctor if you are a nursing mother because safety during lactation is not yet established.

      Drug Interactions:

      Inform your doctor if you are on any medication such as digoxin, methotrexate, diuretic or water pill, ketoconazole, erythromycin, opioid analgesics, and muscarinic.

      Precautions
      • Keep the medicine out of sight and reach of children.
      • Store at room temperature away from heat and moisture.
      • Do not use Life Pan DSR Capsule beyond its expiry.
      FDA Pregnancy Category

      Category N: No information available.


      Drug Composition information
      What is Domperidone for:

      This medication is an antidopaminergic agent, used in treating nausea, vomiting, gastrointestinal problems and Parkinson’s disease.

      How does Domperidone work:

      Domperidone helps the stomach get rid of food and lowers signs of an upset stomach, throwing up, heartburn, and fullness.

      How should Domperidone be used:

      Adult: Oral- Nausea and vomiting- 10-20 mg 4-8 hourly. Max: 80 mgday. Non ulcer dyspepsia- 10-20 mg 3 timesday and at night. Migraine- 20 mg 4 hourly. Max: 4 doses24 hour. Rectal- Nausea and vomiting- 60 mg twice daily. It is available in various forms like tablet, drop, suspension, capsule to take by mouth, on an empty stomach.

      Common side effects of Domperidone :

      Headache. Dry mouth. Good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. See a dentist often

      What do I do if I miss a dose

      Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.

      What precautions should I take when taking Domperidone :

      Alert your doctor if you have stomach problems (such as stomach bleeding or intestinal blockage) or prolactinoma (a tumour that releases a hormone called prolactin). - Alert your doctor if you have heart, liver or kidney disease, or if you have breast cancer. - Alert your doctor if you are pregnant or breastfeeding. Do not breastfeed while being treated with Domperidone.

      When do I need to seek medical help

      If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. A fast heartbeat. Very bad dizziness or passing out. Seizures. Any rash. Side effect or health problem is not better or you are feeling worse.

      Can I take Domperidone with other medicines:

      Alert your doctor quickly if you are taking any of the following medications: - bromocriptine - heart medicines, especially those used to control irregular heartbeat. - antidepressants known as MAOI, such as phenelzine, isocarboxazid. - other mood medicines such as mesoridazine, thioridazine. - painkillers such as codeine, morphine. - Always inform your doctor and pharmacist if you are taking any other medicines, including herbal tonics, supplements and medicines that you buy without a prescription.

      Are there any food restrictions

      Avoid Alcohol

      How do I store Domperidone :

      Oral: Store it at controlled room temperature (15-30°C).

      Pregnancy Category

      Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

      Therapeutic Classification

      Antiemetics, GIT Regulators & Anti-Inflammatories

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