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      Mfg/Mkt: lupin ltd

      LOFTAIR INHALER

      Country of origin: INDIA

      Seller Information

      This product by the manufacturer has been replaced with

      LOFTAIR L 30S CAP & INHALER

      Loftair Inhaler
      Uses and Benefits

      Uses and Benefits

      Loftair Inhaler is a combination medicine used for concomitant therapy with an inhaled corticosteroid in treatment of bronchoconstriction in patients with chronic obstructive pulmonary disease, severe allergic reactions, prevention of exercise induced bronchospasm. It relieves symptoms such as shortness of breath, chest tightness, wheezing and coughing etc reduces side effects of muscle relaxing drugs. It also reduces drooling of saliva in patients with movement disorder occurring in early childhood and other conditions. However, the uses mentioned here are not comprehensive, there may be other conditions for which the medication may be used upon your doctor’s discretion.

      Composition

      Composition

      The active ingredients of Loftair Inhaler are Glycopyrronium bromide (50Mcg) and Indacaterol (110Mcg)

      Mechanism of Action of Drugs

      Mechanism of Action of Drugs

      Loftair Inhaler works by acting locally in the lungs as bronchodilator, for the maintenance treatment of chronic obstructive pulmonary disease. Glycopyrronium bromide, an anticholinergic medication works by blocking the activity of acetylcholine (chemical messenger) in the brain and decreases the secretions in the airways. Formoterol, bronchodilator works by relaxing the muscles in the airways leading to lungs, making breathing easier.

      Contraindications and Cautions

      Contraindications and Caution

      Patients with following conditions are suggested to seek advice from their healthcare professionals before using Loftair Inhaler.

      • Hypersensitivity to any of the ingredients used in the formulation
      • Severe ulcerative colitis
      • Obstructive disease of gastrointestinal tract
      • Paralytic ileus
      • Intestinal atony in elderly or debilitated patients
      • Myasthenia gravis
      • Glaucoma
      • Caution:
      • Cardiovascular diseases
      • Hypersensitivity to milk proteins
      • Diabetes
      • Thyrotoxicosis
      • Autonomic neuropathy
      • Renal and hepatic impairment
      • Children and elderly
      • Pregnancy and lactation
      Side Effects

      Side and Adverse Effects

      The following side effects may or may not occur during the usage of Loftair Inhaler. It is usually well tolerated when taken in the recommended dosage guidelines. More common side effects include:

      • Indigestion
      • Headache
      • Agitation
      • Abdominal pain
      • Dyspnoea
      • Tremors
      • Dizziness
        Insomnia
        Urinary retention
      • Fever
      • Chest pain
      • Nausea and vomiting
      • Reduced bronchial secretions
      • Sinus inflammation

      Rare but more serious adverse effects may include:

      • Dehydration
      • Pharyngitis
      • Upper respiratory tract infection
      • Otitis media
      • Paralysis of ciliary muscle
      • Dry mouth
      • Increased ocular tension
      How to Use

      How to Use

      Take Loftair Inhaler as instructed by your doctor. Do not use this medicine for durations shorter or longer than suggested by your doctor. Avoid missing or forgetting the dose, if you do, take the Loftair Inhaler as soon as remember, however if it’s almost time for your next dose, skip the previous dose and take it according to your normal scheduled time. Continue to use this drug until completion of the maximum amount suggested.
      Loftair Inhaler should be taken with food to avoid stomach upset. Take the medicine at the same time as it helps to maintain a consistent level of medicine in the body.
      Do not swallow the medicine as it is to be taken by inhalation using roto haler. Follow all the instructions carefully as mentioned on the label.

      Overdosage

      Avoid taking medicine more than the prescribed dosage. If you notice any unusual or abnormal reactions after taking the Inhaler, promptly seek medical attention. Depending on the dosage of Loftair inhaler, symptoms vary in individuals, you may experience one or more of the following symptoms:

      • Mydriasis
      • Dry mouth
      • Hypotension
      • Respiratory depression
      Warnings and Precautions

      Use this Inhaler only on the advice of medical practitioner. Dose adjustments or complete avoidance of the Loftair Inhaler may be required in the following conditions:

      Kidney:

      Caution is advised among people with kidney problems. Close monitoring of kidney function and adjustments of dose of the medicine may be needed based on the clinical condition of the patient. If you have any renal problems, it is highly recommended that you consult doctor before the consumption of this medicine.

      Liver:

      Caution is advised among people with liver problems. Dose adjustments of the medicine may be needed. If you have any hepatic problems, it is recommended that you consult doctor before the consumption of this medicine.

      Pregnancy:

      Loftair Inhaler is not considered safe to use in pregnant women unless the potential benefits outweigh the risks involved. Despite the fact that there are limited studies in humans, animal studies have shown no or low adverse effects on the developing baby. It is recommended that you consult your doctor before consumption of this medicine.

      Lactation:

      This medicine is not considered safe to use in nursing mothers unless the potential benefits outweigh the risks involved. Long term use of the medicine reduces milk production. Since the effect of the medicine on infants is not clearly established, we recommend that you to consult your doctor before consuming the medicine.

      Alcohol:

      Consumption of alcohol with Loftair Inhaler is not recommended as it increases side effects of the medicine. If you notice any unusual or abnormal reactions after taking the medicine, report to your doctor immediately.

      Driving:

      Loftair Inhaler may decrease alertness, cause impaired judgement, affect your vision and make you feel dizzy, light headedness, do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

      Food:

      There are no known food interactions with Loftair inhaler.

      Drug Interactions:

      Alert your doctor if you are using Loftair inhaler with any of the below medicines:

      Anticoagulants such as Warfarin
      Monoamine oxidase inhibitors used in treating depression
      Azithromycin, ketoconazole
      Domperidone and metoclopramide used for nausea or vomiting
      Antipsychotics: Phenothiazine, Clozapine, haloperidol
      Antiarrhythmics: Disopyramide
      Amantadine
      Beta blockers
      Tri cyclic anti-depressants
      Steroids
      Inform your doctor or pharmacist if you are taking any other medicines which includes over-the-counter drugs, herbal tonics, supplements and medicines that you buy without a prescription.

      Precautions
      • Do not use this Inhaler post the expiry date
      • Do not use this medication for durations longer than suggested by your doctor
      • Store at room temperature (20-25 degree Celsius)
      FDA Pregnancy Category

      FDA Pregnancy Category

      Category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


      Drug Composition information
      What is Glycopyrronium Bromide for:

      It is used to treat GI (gastrointestinal) ulcers. In surgery, it is used to lower secretions such as saliva.

      How does Glycopyrronium Bromide work:

      Glycopyrrolate lowers acid secretion in the stomach. It lowers secretions.

      How should Glycopyrronium Bromide be used:

      Take with or without food. Take with food if it causes an upset stomach. Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor.

      Common side effects of Glycopyrronium Bromide :

      Hard stools (constipation). Drinking more liquids, working out, or adding fiber to your diet may help. Talk with your doctor about a stool softener or laxative. Dry mouth. Good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. See a dentist often.

      What do I do if I miss a dose

      Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.

      What precautions should I take when taking Glycopyrronium Bromide :

      If you have an allergy to glycopyrrolate or any other part of this drug. Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you have any of these health problems: Bleeding problems, a fast heartbeat, glaucoma, bowel block, myasthenia gravis, slow-moving GI (gastrointestinal) tract, ulcerative colitis, or trouble passing urine.

      When do I need to seek medical help

      If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Very bad dizziness or passing out. Change in thinking clearly and with logic. Not able to pass urine. Any rash. Side effect or health problem is not better or you are feeling worse.

      Can I take Glycopyrronium Bromide with other medicines:

      Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.

      Are there any food restrictions

      Avoid Alcohol

      How do I store Glycopyrronium Bromide :

      Store in a cool, dry place away from the reach of children. - Medicines must not be used past the expiry date.

      Pregnancy Category

      Category D: There is positive evidence of human foetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective).

      Therapeutic Classification

      Antacids, Antireflux Agents & Antiulcerants


      Frequently Asked Questions

      Frequently Asked Questions
      Q1.What is the use of Loftair Inhaler?

      Loftair Inhaler is a combination medicine used for concomitant therapy with an inhaled corticosteroid in treatment of bronchoconstriction in patients with chronic obstructive pulmonary disease, severe allergic reactions, prevention of exercise induced bronchospasm. It relieves symptoms such as shortness of breath, chest tightness, wheezing and coughing etc reduces side effects of muscle relaxing drugs. It also reduces drooling of saliva in patients with movement disorder occurring in early childhood and other conditions.

      Q2.Can we take this medicine daily?

      Take the medicine exactly as prescribed by your doctor for the dosage and duration.

      Q3.How many times Loftair Inhaler can be used in a day?

      Use the medicine exactly as prescribed by your doctor for the dosage and duration.

      Q4.What are the side effects of this medicine?

      The medicine is well tolerated when taken in prescribed dosage guidelines. Most common side effects include nausea, vomiting, indigestion, headache, agitation, abdominal pain, chest pain, dyspnoea, urinary retention, tremors, dizziness, insomnia, reduced bronchial secretions, sinus inflammation. Its use may also lead to extreme but uncommon side effects such as severe dry mouth, dehydration, pharyngitis, sinusitis, upper respiratory tract infection, paralysis of ciliary muscle, otitis media, increased ocular tension.

      Q5.Does this medication make you sleepy?

      Loftair Inhaler may decrease alertness, cause impaired judgement, affect your vision and make you feel dizzy, difficulty in concentration, fatigue, light headedness, do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

      Q6.When should I take the medicine?

      Use the medicine exactly as prescribed by your doctor for the dosage and duration.

      Q7.Is this medicine harmful for health?

      Loftair Inhaler is usually well tolerated when taken in the recommended dosage guidelines. Over dose of the medicine may lead to mydriasis, dry mouth, hypotension, respiratory depression.

      Q8.Can we take this on empty stomach or should take it with food?

      Take the Inhaler with, or just after meals to avoid stomach upset. Increase the intake of fluids to avoid excessive dry mouth caused by the Inhaler, as continued dry mouth can lead to dental disease (gum disease, tooth decay, fungal infection).

      Q9.What are the precautions I need to follow while using the Loftair Inhaler?

      If you ever had impaired kidney function, sever liver impairment or heart disease, let your doctor know before taking this medicine. Inform your doctor about all the medicines you take to ensure that you are healthy. Caution is advised among patients with hypersensitivity to any of the ingredients used in the formulation, severe ulcerative colitis, obstructive disease of gastrointestinal tract, paralytic ileus, intestinal atony in elderly or debilitated patients, myasthenia gravis, glaucoma, cardiovascular diseases, hypersensitivity to milk proteins, diabetes, thyrotoxicosis, autonomic neuropathy, renal and hepatic impairment, children and elderly, pregnancy and lactation.

      Q10.Can I give this medicine to a child?

      This medicine is not recommended for children below 4 years of age since the safety and efficacy of use are not clinically established.

      Q11.How long does the effect of medicine last?

      The amount of time for which this medicine remains active on the body is clinically not determined.

      Q12.Can I use this inhaler during pregnancy?

      Loftair Inhaler is not considered safe to use in pregnant women unless the potential benefits outweigh the risks involved. Despite the fact that there are limited studies in humans, animal studies have shown no or low adverse effects on the developing baby. It is recommended that you consult your doctor before consumption of this medicine.

      Q13.At what time can I take the medicine?

      To get the most benefits, take the medicine preferably at the same time every day and dosing interval must be at least six hours between two doses.

      Q14.Can I take this inhaler without a doctor’s prescription?

      No, do not take the medicine without doctor’s prescription.

      Q15.Is it okay to drink alcohol while I am using this medicine?

      Consumption of alcohol with Loftair Inhaler is not recommended as it increases side effects of the medicine. If you notice any unusual or abnormal reactions after taking the medicine, report to your doctor immediately.

      Q16.How to store the medicine?

      Store the medicine at room temperature (20-25 degree Celsius) in a cool and dry place. Keep the Inhaler according to the instructions mentioned on the pack or label. Store the medicine in the container or the pack it came in, tightly closed.

      Q17.Is there any alternate way to use this medicine?

      Loftair Inhaler is to be taken by inhalation using roto haler. Follow all the instructions carefully as mentioned on the label. If you take them in a way they weren’t intended to be used, you could experience an overdose if the active constituent enters the blood stream too quickly. Alternatively, if it enters your body too slowly, it may never achieve a high enough concentration to be completely functional.

      Q18.For how long should I take the medicine?

      Take the medicine as prescribed by your doctor. Do not stop taking the medicine before completion of the course or without consulting your doctor.

      Q19.By when should I start seeing results of the medicine?

      The amount of time required for this medicine to show its action in the body is 5 minutes. The medicine reaches its maximum level after few weeks.

      Q20.What are the alternate medicines to Loftair Inhaler?

      NISTAMI INHALER, SEQUADRA INHALER

      Seller Information
      Manufactured By

      LUPIN LTD

      a-28/1, m.i.d.c, chikalthana,aurangabad - 431210, india

      Packed By

      LUPIN LTD

      a-28/1, m.i.d.c, chikalthana,aurangabad - 431210, india

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