Madol MR Tablet is used to treat moderate to severe pain and inflammation in adults.It is also used to treat painful muscle spasm associated with musculoskeletal conditions. However, the uses mentioned here are not exhaustive. There may be other conditions for which this medication may be used upon a doctor’s discretion.
The active ingredient of Madol MR Tablet are Chlorzoxazone 250mg, Diclofenac 50mg, and Tramadol 37.5mg.
Chlorzoxazone reduces skeletal muscle spasm and relieves one from pain.
Diclofenac acts by inhibiting the prostaglandin synthesis. Prostaglandins are basically compounds that get produced in huge numbers, as a response to pain, injury or infection. The large production of prostaglandins causes inflammation associated with redness, swelling, pain and fever. Thus by inhibiting their synthesis, Diclofenac treats inflammation and reduces pain.
Tramadol acts by withholding the chemical neurotransmitters which enhance pain. Simultaneously, this drug also enhances the serotonin release which contributes to happiness and well-being by calming and relaxing the mind.
Patients with the following conditions are suggested to seek advice from their health care professionals before taking the Madol MR Tablet:
The following side effects may or may not occur during the usage of this Madol MR Tablet. It is generally well tolerated when taken in the prescribed dosage guidelines. More common ones are generally mild and may include:
Rare but more serious adverse effects may include:
Do not exceed the dose prescribed by your doctor.
Swallow Madol MR Tablet immediately after opening it from the strip. Do not break or chew the Madol MR Tablet.
Avoid missing/forgetting a dose. If you do, take it as soon as you remember; but if it is almost time for your next dose, skip it and take it according to your normal schedule. Don’t consume two doses at the same time which may be dangerous to your health.
Take Madol MR Tablet with or without food.
Take the medication at the prescribed time and dosage.
Avoid taking Madol MR Tablet more than the prescribed dosage. In case of an accidental overdose, promptly seek medical advice. Depending on the dosage, symptoms may vary but you may experience one or more of the following signs or symptoms:
Take Madol MR Tablet only on the advice of a medical practitioner. Dosage adjustment or complete avoidance of the medication may be required in the following conditions:
Caution advised among people with renal problems. If you have any, consult your doctor before the consumption of this Madol MR Tablet.
Caution advised among people with hepatic problems. If you have any, consult your doctor before the consumption of this Madol MR Tablet.
Safety during pregnancy has not yet established and the risk of teratogenicity is expected (chances are low). Therefore, inform your doctor about if you are pregnant or planning to become pregnant during the treatment.
Caution advised during pregnancy. Therefore, inform your doctor if you are a nursing mother during the treatment.
Since consuming this medicine would induce sleep/cause dizziness or impair your thinking or reactions, do not drive, operate heavy machinery or involve in any works which may demand your attention/physical strength
Caution always advised when used with other medicine(s). Therefore, inform your doctor about your previous and current history of medication(s) (if any).
Category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
This medication is a muscle relaxant, prescribed for muscle spasm and the resulting pain or discomfort. It is used in combination with physical therapy, Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) (such as aspirin or acetaminophen), and rest.
Chlorzoxazone works in the brain to ease pain.
Oral: The recommended initial dose is 500 mg 3-4 timesday. May reduce to 250 mg 3-4 timesday subsequently. Max: 750 mg 3-4 timesday. It comes as a tablet to take by mouth. It usually is taken three or four times a day with food.
Feeling lightheaded, sleepy, having blurred eyesight, or a change in thinking clearly. Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how this drug affects you. Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing. Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
Take a missed dose as soon as you think about it. - If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. - Many times this drug is taken on an as needed basis.
If you have an allergy to chlorzoxazone or any other part of this drug. Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you have liver disease. If you are breast-feeding.
If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Signs of low potassium. Very bad dizziness or passing out. Very upset stomach or throwing up. Not able to pass urine. Any rash. Side effect or health problem is not better or you are feeling worse.
Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.
Oral: Store at 15-30°C. Store it in air tight container and keep away from children.
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
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