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    • 10 Units/pack

      MRP 120

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      MIGRAN TAB

      Migran tablet
      Uses and Benefits

      Uses and Benefits

      Migran tablet is a combination medicine used only for treating migraine headaches. It helps to relieve the symptoms such as nausea and vomiting associated with migraine headaches. This medicine improves the flow of blood in your brain, relaxes the brain and prevents abnormal activity of muscles that trigger migraines. It is an effective medicine for preventing migraine attacks but does not treat a headache that has already set in. However, the uses mentioned here are not comprehensive, there may be other conditions for which the medication may be used upon your doctor’s discretion.

      Composition

      Composition

      The active ingredients of Migran tablet are Caffeine (100Mg), Ergotamine (1Mg), Prochlorperazine (2.5Mg) and Paracetamol (250Mg)

      Mechanism of Action of Drugs

      Mechanism of Action of Drugs

      Migraine headaches are thought to be caused from the dilation of blood vessels in the head and affects the blood flow in the brain and surrounding tissues. Ergotamine constricts the blood vessels helps in improving the blood flow in brain and prevents abnormal activity of muscles that trigger migraines, thus effective in preventing migraine attacks. Paracetamol increases the pain threshold. Caffeine aids in body’s absorption of ergotamine and paracetamol which significantly improves their efficacy. Prochlorperazine works by binding to certain receptors and blocks the release of chemical substances that cause vomiting and nausea.

      Contraindications and Cautions

      Contraindications and Caution

      Patients with following conditions are suggested to seek advice from their healthcare professionals before using Migran tablet:

      • Hypersensitivity to any of the ingredients used in the tablet
      • Hyperthyroidism
      • Analgesic nephropathy (kidney disease)
      • Severe hepatic impairment
      • Severe central nervous system depression
      • Concomitant use with CYP3A4 inhibitors (ketoconazole, erythromycin, ritonavir)
      • Pregnancy and lactation
      • Caution:
      • Cardiovascular disorders
      • Chronic malnutrition
      • Tardive dyskinesia
      • Blood cell count
      • Sepsis
      • Peptic ulcer
      • Children and elderly
      Side Effects

      Side and Adverse Effects

      Migran tablet is usually well tolerated when used in the prescribed dosage guidelines. Most side effects are temporary and usually subsides on their own. However, consult your doctor if they persist for a longer duration. You may experience one or more of the following symptoms:

      • Drowsiness or sleepiness
      • Weight gain
      • Increased appetite
      • Unusual weakness or tiredness
      • Breast pain
      • Muscle pain
      • Dry mouth
      • Irregular heartbeat
      • Skin rash
      • Nausea
      • Constipation
      • Fatigue
      • Blocked or runny nose
      • Stomach discomfort
      • Irregular menstrual periods
      How to Use

      How to Use

      Take Migran tablet as instructed by your doctor. Swallow the tablet whole with water, immediately after opening it from the strip. Do not break or crush or chew the tablet.
      Avoid missing or forgetting the dose. If you do, take it as soon as you remember; but if it’s almost time for your next dose, skip it and take it according to your normal schedule. Don’t swallow two doses at the same time which is dangerous to your health.
      The tablet may be taken with or without food. If significant stomach upset occurs, it could be taken with food. Take the tablet at the same time every day as it helps to maintain a consistent level of medicine in the body.
      Do not change the dose or stop taking the medicine before completion of the course or without consulting your doctor. Continue to use this drug until completion of the maximum amount suggested.

      Overdosage

      Avoid taking medicine more than the prescribed dosage. If you notice any unusual or abnormal reactions after taking the tablet, promptly seek medical attention. Depending on the dosage of Migran tablet, symptoms vary in individuals, you may experience one or more of the following symptoms:

      • Extreme thirst
      • Tingling and itching of the skin
      • Rapid and weak pulse
      • Hypotension
      • Convulsions
      • Unconsciousness
      • Diarrhea
      • Coldness and weakness
      Warnings and Precautions

      Warnings and Precautions

      Use this tablet on the advice of medical practitioner. Dose adjustments or complete avoidance of the Migran tablet may be required in the following conditions:

      Kidney:

      Extreme caution is advised among people with kidney problems. Dose adjustments of the tablet may be needed. If you have any hepatic problems, it is highly recommended that you consult doctor before the consuming this medicine.

      Liver:

      Extreme caution is advised among people with liver problems. Dose adjustments of the tablet may be needed. If you have any hepatic problems, it is highly recommended that you consult doctor before the consuming this medicine.

      Pregnancy:

      Migran is not considered safe to use in pregnant women unless the potential benefits outweigh the risks involved. Despite the fact that there are limited studies in human beings, animal studies have shown harmful effects on the developing baby. It is recommended that you consult your doctor before consuming this medicine.

      Lactation:

      The medicine is likely unsafe to use for nursing mothers. Limited human data suggests that the medication may pass into the breastmilk and harm the infant. Consult your doctor immediately if the baby shows signs of increased sleepiness, breathing problems or difficulty in breast feeding.

      Alcohol:

      Consumption of alcohol with this tablet is not recommended as it increases side effects such as drowsiness, difficulty in concentration, weakness, joint pain, fever, jaundice. Any symptoms of abnormal reactions after taking the medicine should be reported to your doctor immediately.

      Driving:

      The tablet may decrease alertness, cause impaired judgement, affect your vision and make you feel dizzy, light headedness. Do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

      Food:

      There are no known food interactions with this medicine.

      Drug Interactions:

      Inform your doctor or pharmacist if you are taking any other medicines which includes over-the-counter drugs, herbal tonics, supplements and medicines that you buy without a prescription. Alert your doctor if you are taking Migran tablet with lithium, indinavir, ritonavir, progesterone, disulfiram, quinolone antibiotics, cyclizine, sumatriptan, phenytoin, nicotine, beta blockers, theophylline, probenecid, warfarin, antidiabetic medicines, tramadol.

      Precautions
      • Do not use this tablet post the expiry date
      • Do not use this medication for durations longer than suggested by your doctor
      • Store at room temperature (20-30 degree Celsius)
      FDA Pregnancy Category

      FDA Pregnancy Category

      Category X: Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.


      Drug Composition information
      What is Caffeine for:

      This medication stimulates the brain; hence it is used as a central nervous stimulant. It is used along with Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) andor ergotamine for migraine (severe headaches with nausea). It is also used for a breathing condition (apnea) in premature infants.

      How does Caffeine work:

      Caffeine fires up the brain.

      How should Caffeine be used:

      It may be administered orally at a dose of 100-200 mg , repeated after 3-4 hours as needed. For apnea in premature babies, it is administered intravenously or orally at an initial dose of 20 mgkg, followed by 5 mgkgday. It comes as a tablet, capsule to take by mouth. It is also available in injection, administered by the healthcare providers, directly into the vein.

      Common side effects of Caffeine :

      Nervous and excitable. - Grouchy or touchy. Not able to sleep.

      What do I do if I miss a dose

      Take a missed dose as soon as you think about it. - If it is close to the time for your next dose, skip the missed dose and go back to your normal time. - Do not take 2 doses at the same time or extra doses. Many times this drug is taken on an as needed basis.

      What precautions should I take when taking Caffeine :

      If you have an allergy to caffeine or any other part of this drug. - Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.

      When do I need to seek medical help

      If you think there was an overdose, call your local poison control center or ER right away. - Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. A fast heartbeat. Very nervous and excitable. Any rash. Side effect or health problem is not better or you are feeling worse.

      Can I take Caffeine with other medicines:

      Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.

      Are there any food restrictions

      Avoid Alcohol

      How do I store Caffeine :

      Store it 25°C. Store it in air tight container and keep away from children.

      Pregnancy Category

      Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

      Therapeutic Classification

      Respiratory Stimulants, Antimigraine Preparations, Other CNS Drugs & Agents for ADHD


      Frequently Asked Questions

      Frequently Asked Questions
      Q1. What is the use of the Migran tablet?

      It is a combination medicine used only for treating migraine headaches. It helps to relieve the symptoms such as nausea and vomiting associated with migraine headaches. This medicine improves the flow of blood in your brain, relaxes the brain and prevents abnormal activity of muscles that trigger migraines. It is an effective medicine for preventing migraine attacks but does not treat a headache that has already set in.

      Q2. What are the side effects of the Migran tablet?

      The tablet is well tolerated when taken in prescribed dosage guidelines. Most common side effects include depression, drowsiness or sleepiness, weight gain, increased appetite, unusual weakness or tiredness, breast pain, dry mouth, irregular heartbeat, skin rash, nausea, constipation, fatigue, stomach discomfort, blocked or runny nose, irregular menstrual periods, swelling of face, eyelids, tongue, hands and feet.

      Q3. Should we take Migran tablet with food or without food?

      The tablet may be taken with or without food. If significant stomach upset occurs, it could be taken with food.

      Q4. What are the precautions to be followed while taking the Migran tablet?

      If you ever had impaired kidney function, sever liver impairment or heart disease, let your doctor know before taking this medicine. Inform your doctor about all the medicines you take to ensure that you are healthy. This medicine is contraindicated in patients with hypersensitivity to any of the ingredients used in the tablet, hyperthyroidism, analgesic nephropathy (kidney disease), severe hepatic impairment, severe central nervous system depression, concomitant use with CYP3A4 inhibitors (ketoconazole, erythromycin, ritonavir), pregnancy and lactation. Caution is advised among patients with cardiovascular disorders, chronic malnutrition, tardive dyskinesia, blood cell count, sepsis, peptic ulcer, children and elderly.

      Q5. Does Migran tablet make you sleepy?

      The tablet may decrease alertness, impaired judgement, affect your vision and make you feel dizzy, light headedness. Do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

      Q6. Is Migran tablet harmful? What does an overdose of Migran tablet lead to?

      The tablet is usually well tolerated when taken in the recommended dosage guidelines. Over dose of the medicine may lead to extreme thirst, tingling and itching of the skin, rapid and weak pulse, hypotension, convulsions, unconsciousness, diarrhea, coldness and weakness.

      Q7. Can I take Migran tablet during pregnancy?

      The tablet is not considered safe to use in pregnant women unless the potential benefits outweigh the risks involved. Despite the fact that there are limited studies in human beings, animal studies have shown harmful effects on the developing baby. It is recommended that you consult your doctor before consuming this medicine.

      Q8. Can Migran tablet be taken without a doctor’s prescription?

      No, do not take the medicine without doctor’s prescription.

      Q9. Is it okay to drink alcohol while I am on the Migran tablet?

      Consumption of alcohol with this tablet is not recommended as it increases side effects such as drowsiness, difficulty in concentration, weakness, joint pain, fever, jaundice. Any symptoms of abnormal reactions after taking the medicine should be reported to your doctor immediately.

      Q10. How to store Migran tablet?

      Store the medicine at room temperature (20-30 degree Celsius) in a cool and dry place. Keep the tablet according to the instructions mentioned on the pack or label. Store the medicine in the container or the pack it came in, tightly closed.

      Q11. If I have trouble swallowing Migran tablet, can I mix it in water and drink it?

      This tablet is designed to be swallowed with water. If you take them in a way they weren’t intended to be used, you could experience an overdose if the active constituent enters the blood stream too quickly. Alternatively, if it enters your body too slowly, it may never achieve a high enough concentration to be completely functional.

      Q12. Can we give Migran tablet to children?

      This tablet is not recommended for children below 18 years of age since the safety and efficacy of use are not clinically established.

      Q13. By when should I start seeing the results of the Migran tablet?

      The amount of time required for this medicine to show its action in the body is clinically not determined.

      Q14. How long does the effect of Migran tablet last?

      The duration for which this medicine remains active in the body is clinically not determined.

      Q15. Can we take Migran tablet daily? If yes, how many tablets can we take everyday?

      Medicines should always be taken under medical supervision. Take the medicine exactly as prescribed by your doctor: for dosage and duration. Most recommended dose is one tablet a day.

      Q16. For how many days should I take the Migran tablet?

      The number of days that any medicine must be taken varies from patient to patient; and case to case. So always stick to your doctor’s suggestion about how many days to take this medicine.

      Q17. When should I take Migran tablet?

      Use the medicine exactly as prescribed by your doctor for the dosage and duration.

      Note: All of the above information is for reference purpose only. It is always recommended that you consult a medical professional.

      Seller Information
      Manufactured By

      LEEFORD HEALTHCARE LTD

      203,mangalam,kulpawadi,borivali mumbai 400066

      Packed By

      LEEFORD HEALTHCARE LTD

      203,mangalam,kulpawadi,borivali mumbai 400066

      Applicable Offers

      • 20% Discount
        On prescription medicines, orders above Rs 1000 T & C

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