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Mfg/Mkt: cipla


Country of origin: INDIA

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10 Units/pack

MRP 57

Inclusive of all Taxes

FLAT 20% OFF On bills above 1000.0

Nicip Plus Tablet
Uses and Benefits

Uses and Benefits

Nicip Plus Tablet is an anti-inflammatory, antipyretic, and analgesic medicine used to treat medical conditions such as acute pain, fever, symptomatic treatment of osteoarthritis, and primary dysmenorrhoea in people above 12 years. However, the uses mentioned here are not exhaustive. There may be other conditions for which this medication may be used upon a doctor’s discretion.



The active ingredients of Nicip Plus Tablet are Nimesulide 100mg and Paracetamol (also known as Acetaminophen) 500mg.

Mechanism of Action of Drugs

Mechanism of Action of Drugs

Nimesulide acts by targeting several key mediators in the inflammatory process such as Cox-2 mediated prostaglandins, free radicals, a proteolytic enzyme, and histamine. This is how it switches off the activities which cause inflammation, fever, and pain.

On the other hand, Paracetamol (or Acetaminophen) primarily acts as an analgesic and an antipyretic agent. It also possesses anti-inflammatory properties. It produces its analgesic effects by increasing the pain threshold and antipyresis by acting on the hypothalamic heat-regulating center.

Contraindications and Cautions

Contraindications and Caution

Patients with the following conditions are suggested to seek advice from their health care professional before using this Nicip Plus Tablet:

  • Hypersensitivity to any of the drugs used in the Nicip Plus Tablet such as Nimesulide or Paracetamol (Acetaminophen)
  • GI Bleeding
  • Active peptic ulcer disease
  • Renal or heart failure (severe)
  • Hepatic impairment
  • Coagulation disorder
  • Caution:
  • Hepatic impairment (mild-Moderate)
  • Active hepatic disease (mild-moderate)
  • Hypovolemia (severe)
  • Malnutriton (severe)
  • Chronic alcohol use
Side Effects

Side and Adverse Effects

The following side effects may or may not occur during the usage of this Nicip Plus Tablet. It is generally well tolerated when taken in the prescribed dosage guidelines. More common ones are generally mild and may include:

  • Nausea
  • Vomiting
  • Headache
  • Insomnia
  • Constipation
  • Pruritis
  • Agitation
  • Rash
  • Epigastric discomfort
  • Heartburn or abdominal cramps
  • Edema
  • Dizziness
  • Drowsiness

Rare but more serious adverse effects may include:

  • Fatal hepatitis
  • Stevens-johnson syndrome
  • Anaphylaxis
  • Hepatotoxicity
  • Renal tubular necrosis (acute)
  • Anemia
  • Hypokalemia
  • Thrombocytopenia
  • Analgesic associated nephropathy (chronic use)
How to Use

How to Use

Do not exceed the dose prescribed by your doctor.
Swallow the tablet whole, immediately after opening it from the strip. Do not break or chew the tablet whole.
Avoid missing a dose. If you do, take it as soon as you remember; but if it is almost time for your next dose, skip it and take it according to your normal schedule. Don’t consume two doses at the same time which may be dangerous to your health.
Nicip Plus Tablet may be taken with food.
Take the medicine at the prescribed time and dosage.


Avoid taking more than the prescribed dosage. In case of an accidental overdose, promptly seek medical advice. Depending on the dosage, symptoms may vary but you may experience one or more of the following signs or symptoms:

  • Epigastric pain
  • Nausea
  • Vomiting
  • Lethargy
  • Seizures
  • Hypertension
  • Coma
  • Apnoea
  • Anaphylactic reactions
  • Renal failure
Warnings and Precautions

Warnings and Precautions

Take the Nicip Plus Tablet only on the advice of a medical practitioner. Dosage adjustment or complete avoidance of the medication may be required in the following conditions:


Inform your doctor if you have any renal problems before using the Nicip Plus Tablet.


Do not take this medicine if you have any severe liver disease. Talk to your doctor about your condition before consuming the tablet.


Nimesulide: Do not take this drug if you are pregnant. The use of this drug during pregnancy is contraindicated because its adverse effects on the fetus are not known.
Paracetamol (Acetaminophen): May be used during pregnancy; there is no known risk of fetal harm based on human data with short term use of Paracetamol (Acetaminophen).


Nimesulide: No scientific studies are available to show the effect of this drug on breastmilk production. Therefore, it is not recommended to use this medicine during breastfeed.
Paracetamol (Acetaminophen): May be used during pregnancy – no known risk to the breastfed infant based on human studies with oral form. And, no human data are available to evaluate the effects of medicine on milk production.


Avoid taking alcohol. This may increase your hepatic risk.

Drug Interactions:

Caution always advised when used with other OTC drugs and herbal supplements. Therefore, inform your doctor about your current list of medication or if any other medicines which you carry on with or discontinued.

  • Keep the medicine from out of sight and reach of children.
  • Store it in cool temperature away from heat and moisture.
  • Do not use the Nicip Plus Tablet beyond its expiry.
FDA Pregnancy Category

FDA Pregnancy Category

Category N: No information available.

Drug Composition information
What is Nimesulide for:

This medication is a non-steroidal anti-inflammatory drug.

How does Nimesulide work:

This drug is prescribed for painful inflammatory conditions, back pain, dysmenorrhea, postoperative pain, osteoarthritis, and fever.

How should Nimesulide be used:

Take Nimesulide exactly as directed by your doctor. Do not take more than instructed by your doctor.

Common side effects of Nimesulide :

Nimesulide may cause dizziness. If you feel dizzy, do not drive or take part in any activity in which you need to be alert. Nimesulide is likely to cause stomach discomfort such as nausea, diarrhoea and stomach pain. Be sure to take it with food. This will help minimise the stomach discomfort.

What do I do if I miss a dose

Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.

What precautions should I take when taking Nimesulide :

Do not take Nimesulide if you: - are pregnant or breastfeeding. - have a history of allergic reactions (swollen eyes or mouth, difficulty breathing, rashes) to similar medicines such as aspirin, diclofenac, mefenamic acid, ibuprofen, indomethacin, ketoprofen, naproxen or piroxicam. - asthma - stomach ulcers or bleeding from the stomach. - problems with blood clotting.

When do I need to seek medical help

If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Signs of infection.

Can I take Nimesulide with other medicines:

Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.

Are there any food restrictions

Avoid Alcohol

How do I store Nimesulide :

Store in a cool, dry place away from the reach of children. - Medicines must not be used past the expiry date.

Pregnancy Category

Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Therapeutic Classification

Nonsteroidal Anti-Inflammatory Drugs (NSAIDs), Non-Opioid Analgesics & Antipyretics

Seller Information
Manufactured By


vema indl estate goa 403722 india

Packed By


vema indl estate goa 403722 india

Applicable Offers

  • 20% Discount
    On prescription medicines, orders above Rs 1000 T & C
  • 10% Discount
    On prescription medicines, orders above Rs 200 T & C

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