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Oreo Mr Tab
Uses and Benefits

Uses and Benefits

Oreo MR Tablet is a combination medicine used for the treatment of pain, swelling and inflammation associated with muscle spasm. It is used in moderate to severe pain relief. The tablet is used in the treatment of rheumatoid arthritis, osteoarthritis, bursitis, tendinitis, dysmenorrhea. The tablet effectively relieves muscle stiffness, thereby improving muscle movement. However, the uses mentioned here are not exhaustive, there may be other conditions for which the medication may be used upon your doctor’s discretion.

Composition

Composition

The active ingredients of Oreo MR tablet are Etoricoxib (60mg) and Thiocolchicoside (4Mg).

Mechanism of Action of Drugs

Mechanism of Action of Drugs

Etoricoxib is a pain-relieving medicine which works by blocking the release of certain chemical messengers in the brain that cause pain and inflammation.

Thiocolchicoside works on the certain receptors in the brain and spinal cord to prevent muscle contractions and relieve muscle spasms or stiffness.

Contraindications and Cautions

Contraindications and Caution

Patients with following conditions are suggested to seek advice from their healthcare professionals before using Oreo MR tablet.

  • Hypersensitivity to any of the ingredients used in the tablet formulation.
  • Gastrointestinal bleeding
  • Inflammatory bowel disease
  • Acute rhinitis
  • Peptic ulcers
  • Ischaemic heart disease
  • History of bronchospasm
  • Peripheral arterial disease
  • Cerebrovascular disease
  • Pregnancy
  • Caution:
  • Asthma
  • Mild to moderate hepatic impairment
  • History of cardiac failure
  • Diabetes mellitus
  • Elderly and lactation
  • Urticaria
Side Effects

Side and Adverse Effects

The following side effects may or may not occur during the usage of Oreo MR tablet. It is usually well tolerated when taken in the recommended dosage guidelines. More common side effects include:

  • Heartburn
  • Tinnitus
  • Nausea
  • Diarrhea
  • Dyspepsia
  • Abdominal pain
  • Gastritis
  • Loss of appetite
  • Fluid retention
  • Oral ulcer

Rare but more serious adverse effects may include:

  • Exfoliative dermatitis
  • Gastrointestinal bleeding
  • Toxic epidermal necrolysis
  • Palpitations
  • Arrythmias
  • Photosensitivity reactions
How to Use

How to Use

Take Oreo MR tablet as instructed by your health care professional. Do not use this pill for durations shorter or longer than suggested by your doctor. Avoid missing or forgetting the dose. If you do, take the tablet as soon as remember, but its almost time for your next dose, skip the previous dose and take it according to your normal scheduled time. Continue to use this drug until completion of the maximum amount suggested.

Oreo MR tablet should be taken with food, milk or an antacid to avoid stomach upset. The tablet is usually taken not more than 3-4 times a day.

Overdosage

Avoid taking medicine more than the prescribed dosage. If you notice any unusual or abnormal reactions after taking the tablet, promptly seek medical attention. Depending on the dosage of Oreo MR tablet, symptoms vary in individuals, you may experience one or more of the following symptoms:

  • Gastrointestinal events
  • Cardiorenal events
  • Angioedema
  • Difficult or trouble breathing
Warnings and Precautions

Warnings and Precautions

Use this tablet on the advice of medical practitioner. Dose adjustments or complete avoidance of the Oreo MR tablet may be required in the following conditions:

Kidney:

Caution is advised among people with kidney problems as prolonged use of the medicine may cause painful urination and protein or blood in urine. Adjustments of dose of the medicine may be needed. If you have any renal problems, it is highly recommended that you consult doctor before the consumption of this medicine.

Liver:

Caution is advised among people with liver problems. Dose adjustments of the Oreo MR tablet may be needed. If you have any hepatic problems, it is highly recommended that you consult doctor before the consumption of this medicine. However, use of this tablet is not suggested in patients with moderate to severe liver diseases.

Pregnancy:

Oreo MR tablet might be risky to use during pregnancy. Despite the fact that there are limited studies in human beings, animal studies have shown effects on the developing baby. It is recommended that you consult your doctor before consuming this medicine.

Lactation:

The medicine is likely unsafe to use for nursing mothers. Limited human data suggests that the medication may pass into the breastmilk and harm the infant. Consult your doctor immediately if the baby shows signs of increased sleepiness, breathing problems or difficulty in breast feeding.

Alcohol:

Consumption of alcohol with Oreo MR tablet is not recommended as it increases side effects such as gastrointestinal bleeding, dizziness, light headedness. If there are any signs of discomfort or any natural reactions after taking the tablet, report to your doctor immediately.

Driving:

Oreo MR tablet may decrease alertness, cause impaired judgement, affect your vision and make you feel dizzy, light headedness, do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

Food:

Avoid grape fruit juice and alcohol as it may alter serum levels.

Drug Interactions:

Alert your doctor if you are taking Oreo MR tab with any of the below medicines:

  • Sodium nitrite
  • Carbamazepine
  • Phenytoin
  • Ramipril, Propranolol
  • Rifampicin
  • Leflunomide
  • Methotrexate, ethinylestradiol, Lithium – increased plasma concentrations
  • Glimepiride
  • Anticoagulants: Warfarin
  • Diuretics

Inform your doctor or pharmacist if you are taking any other medicines which includes over-the-counter drugs, herbal tonics, supplements and medicines that you buy without a prescription.

Precautions
  • Do not use this tablet post the expiry date
  • Do not use this medication for durations longer than suggested by your doctor
  • Store at room temperature (20-30 degree Celsius)
FDA Pregnancy Category

FDA Pregnancy Category

Category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


Drug Composition information
What is Etoricoxib for:

This medication is a non-steroidal anti-inflammatory drug (NSAID), prescribed for osteoarthritis, rheumatoid arthritis and gouty arthritis. It blocks a substance in the body named as cyclo-oxygenase-2 (COX-2).

How does Etoricoxib work:

It may also be used to provide relief in gout, Osteoarthritis (OA), Rheumatoid Arthritis (RA) and other similar conditions.

How should Etoricoxib be used:

PO- Adult- The recommended dosage is 60 to 120mg once daily. It comes as a tablet to take by mouth, with or without food.

Common side effects of Etoricoxib :

Alert your doctor if any of the following symptoms are severe or refuse to go away: - swelling of hands and legs. - rashes. - diarrhoea. - stomach pain. - tiredness.

What do I do if I miss a dose

Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.

What precautions should I take when taking Etoricoxib :

Do not take Etoricoxib if you have a history of allergic reactions (swollen eyes or mouth, difficulty breathing, rashes) to similar medicines such as aspirin, celecoxib, diclofenac, mefenamic acid, ibuprofen, indomethacin. Always ask your doctor or pharmacist if you are not sure. Etoricoxib may not be suitable for you if you have a history of heart, kidney, liver or blood clotting problems, stroke, high blood pressure, bowel inflammation or stomach ulcers. Alert your doctor if you have any of these conditions.

When do I need to seek medical help

If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Signs of infection. These include a fever of 100.5°F (39°C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain. Very bad belly pain. Trouble breathing. Cough that does not go away. Very upset stomach or throwing up. Very loose stools (diarrhea). Any bruising or bleeding. Dark urine or yellow skin or eyes. Not able to eat. Feeling very tired or weak. Any rash. Side effect or health problem is not better or you are feeling worse.

Can I take Etoricoxib with other medicines:

Inform your doctor and pharmacist if you are taking any of the following medicines: - aspirin. - medicines that affect blood clotting such as warfarin, clopidogrel, dipyridamole, heparin. - furosemide. - lithium. - steroids such as dexamethasone, prednisolone. - rifampicin. - methotrexate. - Always inform your doctor and pharmacist if you are taking any other medicines, including herbal tonics, supplements and medicines that you buy without a prescription.

Are there any food restrictions

Avoid Alcohol

How do I store Etoricoxib :

Store it in refrigerator.

Pregnancy Category

Category X : Studies in animals or humans have demonstrated fetal abnormalities andor there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.

Therapeutic Classification

Nonsteroidal Anti-Inflammatory Drugs (NSAIDs), Non-Opioid Analgesics & Antipyretics


Frequently Asked Questions

Frequently Asked Questions

What is the use of Oreo MR tablet?

Oreo MR Tablet is a combination medicine used for the treatment of pain, swelling and inflammation associated with muscle spasm. It is used in moderate to severe pain relief. The tablet is used in the treatment of rheumatoid arthritis, osteoarthritis, bursitis, tendinitis, dysmenorrhea. The tablet effectively relieves muscle stiffness, thereby improving muscle movement.

Can we take this medicine daily?

Take the medicine exactly as prescribed by your doctor for the dosage and duration.

How many Oreo MR tablets can be taken in a day?

Take the medicine exactly as prescribed by your doctor for the dosage and duration. Most recommended dose is two tablets per day. Do not exceed three tablets in a day.

What are the side effects of this medicine?

The tablet is well tolerated when taken in prescribed dosage guidelines. Most common side effects include heartburn, tinnitus, nausea, diarrhea, dyspepsia, abdominal pain, gastritis, loss of appetite, fluid retention, oral ulcers. Its use may also lead to extreme but uncommon side effects such as exfoliative dermatitis, gastrointestinal bleeding, toxic epidermal necrolysis, palpitations, arrythmias, photosensitivity reactions.

 

Does this medication make you sleepy?

Oreo MR tablet may decrease alertness, impaired judgement, affect your vision and make you feel dizzy, light headedness, so do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

When should I take the medicine?

Use the medicine exactly as prescribed by your doctor for the dosage and duration. If you have been prescribed to take one dose each day, take it in the morning. If you have been prescribed two doses each day, take one in the morning and one in the evening.

 

Is this medicine harmful for health?

Oreo MR tablet is usually well tolerated when taken in the recommended dosage guidelines. Over dose of the medicine may lead to gastrointestinal events, cardiorenal events, angioedema drowsiness, difficult and irregular breathing.

Can we take this on empty stomach or should take it with food?

The tablet can be taken with or without food. If significant stomach upset occurs, it could be taken with food.

What are the precautions I need to follow while taking the Oreo MR tablet?

If you ever had impaired kidney function, sever liver impairment or heart disease, let your doctor know before taking this medicine. Inform your doctor about all the medicines you take to ensure that you are healthy. Caution is advised for people with gastrointestinal bleeding, inflammatory bowel disease, acute rhinitis, peptic ulcers, ischaemic heart disease, history of bronchospasm and cardiac failure, peripheral arterial disease, cerebrovascular disease, pregnancy, asthma, mild to moderate hepatic impairment, diabetes mellitus, urticaria, elderly and lactation.

Can I give this medicine to a child?

This tablet is not recommended for children below 16 years of age since the safety and efficacy of use are not clinically established.

How long does the effect of medicine last?

The amount of time for which this medicine remains active on the body is 12 hours.

Can I take this medicine during pregnancy?

Oreo MR tablet might be risky to use during pregnancy. Despite the fact that there are limited studies in human beings, animal studies have shown effects on the developing baby. It is recommended that you consult your doctor before consuming this medicine.

At what time can I take the medicine?

To get the most benefits, take the medicine preferably at the same time every day and dosing interval must be at least six hours between two doses.

Can I take this tablet without a doctor’s prescription?

No, do not take the medicine without doctor’s prescription.

Is it okay to drink alcohol while I am using this medicine?

Consumption of alcohol with Oreo MR tablet is not recommended as it increases side effects such as gastrointestinal bleeding, dizziness, light headedness. Any symptoms of bleeding such as coughing up blood or blood in the stools, report to your doctor immediately.

How to store the medicine?

Store the medicine at room temperature (15-30 degree Celsius) in a cool and dry place. Keep the tablet according to the instructions mentioned on the pack or label. Store the medicine in the container or the pack it came in, tightly closed.

 

If I have trouble swallowing this tablet, can I mix it in water and drink?

Oreo MR tablet is designed to be swallowed with water. If you take them in a way they weren’t intended to be used, you could experience an overdose if the active constituent enters the blood stream too quickly. Alternatively, if it enters your body too slowly, it may never achieve a high enough concentration to be completely functional.

 

For how long should I take the medicine?

Take the medicine as prescribed by your doctor. Do not stop taking the medicine before completion of the course or without consulting your doctor.

By when should I start seeing results of the medicine?

The amount of time required for this medicine to show its action on the body is 1-2 hours of administration.

What are the alternate medicines to Oreo MR tablet?

Etoshine MR Tablet

Retoz MR Tablet

Etofine MR Tablet

Etoford MR Tablet

Etoril MR Tablet

Note: All the above information is for reference purpose only. It is always recommended that you consult a medical professional to be sure.

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