This medication is an antidepressant, prescribed for depression. It blocks the activity of acetylcholine and histamine and affects the action of serotonin and norepinephrine.
Doxepin raises chemicals in the brain. With low mood (depression), sleep and eating habits may get better fast. Other signs may take up to 4 to 6 weeks to get better.
Adult: PO- Initial: 75 mgday, up to 300 mgday in severely depressed patients. Total daily dose is more than 100 mg should be given in divided doses. It comes as a capsule and syrup to take by mouth, with or without food.
Feeling lightheaded, sleepy, having blurred eyesight, or a change in thinking clearly. Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how this drug affects you. Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing. Hard stools (constipation). Drinking more liquids, working out, or adding fiber to your diet may help. Talk with your doctor about a stool softener or laxative. Dry mouth. Good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. See a dentist often.
Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.
If you have an allergy to doxepin or any other part of this drug. Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you have any of these health problems: Trouble passing urine or glaucoma. If you have taken isocarboxazid, phenelzine, or tranylcypromine in the last 14 days. Monoamine oxidase inhibitors (eg, isocarboxazid, phenelzine, and tranylcypromine) must be stopped 14 days before this drug is started. Taking both at the same time could cause risky high blood pressure.
If you think there was an overdose, call your local poison control center or ER right away. - Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. If you are planning to harm yourself or the want to harm yourself gets worse. A fast heartbeat. Very bad dizziness or passing out. Change in thinking clearly and with logic. Not able to pass urine. Feeling very tired or weak. Very nervous and excitable. Driving or doing other tasks or actions that you do not remember doing after taking this drug. Any rash. Side effect or health problem is not better or you are feeling worse.
Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.
Store it at room temperature, and in an airtight container.
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
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