SIGNOFLAM TH 4 TAB

Uses and Benefits

Signoflam TH 4 Tab is a muscle relaxant used to relieve pain and swelling associated with post-operative wounds, muscle pains, joint pains and postoperative pain in ailments like rheumatoid arthritis, ankylosing spondylitis and osteoarthritis. However, the uses mentioned here may not be exhaustive. There may be other reasons or situations in which this medicine might be used.

Composition

The active ingredients of Signoflam TH 4 Tab are Aceclofenac 100 MG+Paracetamol 325 MG+Thiocolchicoside 4 MG.

Mechanism of Action of Drugs

Aceclofenac in Signoflam TH 4 Tab works by blocking the effect of natural substances called cyclo-oxygenase (COX) enzymes which help to make other pain and inflammation causing chemicals in the body, called prostaglandins. Signoflam TH 4 Tab has paracetamol which works by blocking chemical messengers in the brain that tell us we have pain and also reduces a high body temperature by affecting the chemical messengers in an area of the brain that regulates it. The other component is thiocolchicoside which is used for muscle relaxation and to relieve painful spasms of the skeletal muscles.

Contraindications and Caution

Patients with the following conditions are suggested to seek advice from their health care professionals before taking this medicine

• Hypersensitivity or allergy to Signoflam TH 4 Tab or any of its components
• Allergy to any other drugs
• Liver disease
• Kidney ailments
• Heart disease
• Stomach ulcers or bleeding
• High Blood Pressure
• Blood clotting disorders
• Asthma

Caution:

It is very important to tell your doctor about your complete medical history. Before taking this medicine tell your doctor or pharmacist if you are

• Pregnant or breastfeeding

Side and Adverse Effects

Signoflam TH 4 Tab is generally well tolerated when taken in the prescribed dosage guidelines. Most side-effects are usually mild and resolve on their own. However, if they seem to persist for a longer duration of time, please consult your doctor. The following side effects may or may not occur during the usage of this medicine. Some common side-effects are as follows:

• Allergic reactions to any of the compounds in this tab
• Nausea, vomiting (with or without blood)
• Stomach pain
• Indigestion
• Constipation
• Mouth ulcers
• Black stools
• Loose motions
• Excess sleepiness
• Elevated levels of liver enzymes and creatinine

How to Use

Signoflam TH 4 Tab can be taken with food or on an empty stomach. The dose and duration should be followed as prescribed by your doctor. It is best to take this medicine at a fixed time. It is important that this medicine should not be taken more than the recommended dose.

Swallow it whole with water, immediately after opening the tablet from the strip. Do not try to break/crush/chew the tablet.

Avoid missing or forgetting a dose. If you do, take Signoflam TH 4 Tab as soon as you remember but if it is almost time for your next dose, skip the missed dose and take it at the next scheduled time. Do not take two doses at the same time.

Signoflam TH 4 Tab should be taken only by the person for whom it has been recommended by a qualified physician.

Warnings and Precautions

It is best to take of Signoflam TH 4 Tab only on the advice of a medical practitioner. Adjustment of dosage or avoidance of the medication may be required in the following conditions:

Kidney:

safe to use in case of any kidney ailment/disorder? Signoflam TH 4 Tab may make it hard for your kidneys to perform essential tasks like getting rid of waste from the body, keeping your blood pressure steady, making red blood cells. Also, if your kidneys are already damaged, be sure to tell your doctor.

Liver:

safe to use in case of any liver ailment/disorder? Signoflam TH 4 Tabmay be unsafe to use by patients with liver ailments. This medicine may harm the liver and people with liver disease may be at increased risk of developing severe complications. Tell your doctor in order to make sure the medicine is helping you and not causing any harm.

Pregnancy:

safe to use in pregnant women? This medicine may be unsafe for pregnant women. Although only limited studies have been carried out in humans, studies done on animals have shown harmful effects on the developing baby.  This medicine is a powerful medicine and therefore, it should be taken by pregnant women only when recommended by the physician. The doctor will weigh the benefits and any potential risks before prescribing this medicine.

Lactation:

safe to use in breastfeeding women? Signoflam TH 4 Tab may be unsafe and may lead to serious and adverse side effects if you are breastfeeding. This tablet should not be taken unless your doctor says it is necessary to use during breastfeeding. Studies have shown that a small amount of the drug may pass into the breastmilk and harm the baby. Whether this medicine may be used or not by a breast-feeding mother should be decided by the doctor.

Alcohol:

is it okay to consume alcohol during the use of this medicine? Mixing alcohol and medications may increase the risk of adverse reactions or complications, decrease the effectiveness of medications or even render them useless. Interactions of alcohol with drugs may make them harmful or even toxic to the body. Consumption of alcohol is not advisable. Please consult your doctor.

Driving:

does this medicine make you dizzy/ interfere with your sleep? Most people do not realize that many prescription and over-the-counter medicines can cause drowsiness and impair the ability to drive, thus making driving dangerous for themselves and others. If you notice any abnormal changes after ingesting this medicine, it is better to avoid driving. Please consult your doctor.

Food:

Interactions between food and drugs may inadvertently reduce or increase the effect of the drug. Some commonly used herbs, fruits or other ingredients may cause failure of the therapy or even cause serious alterations of the patient’s health. This medicine can be taken with food or without it but it is not known whether there are any interactions with food. Please consult your doctor.

Drug Interactions:

Drug interactions may be dangerous as they could change how your medications work or increase your risk for serious side effects. Be sure to keep a list of all the medicines you use for other illnesses including prescription medicines and herbal products in order to share it with your doctor. Do not start Signoflam TH 4 Tab on your own. Please consult your doctor.

FDA Pregnancy Category

Category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.