This medication is an antiestrogen, prescribed for breast cancer. It is also used for infertility, gynecomastia, ductal carcinoma either alone or with other medications. It blocks the actions of estrogen.
Tamoxifen stops estrogen from feeding estrogen-dependent cancer cells. This lowers the chance for spread of the cancer. It helps start egg release (ovulation).
It comes as a tablet to take by mouth, with or without food. The recommended dose is 20 mg in 1-2 divided doses. Max: 80 mgday.
Flushing. Wearing layers of clothes or summer clothes and staying in cool places may help. Upset stomach. Change in sex ability. This most often goes back to normal. For women, vaginal yeast infection. Report itching or discharge. Mood changes. Weight loss. Feeling tired or weak. Uterine cancer may rarely happen. Stroke and blood clots may rarely happen.
Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.
If you have an allergy to tamoxifen or any other part of this drug. Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you have blood clots or have had blood clots in the past. If you are pregnant or may be pregnant. If you are breast-feeding.
If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Chest pain or pressure. Trouble breathing. Swelling, warmth, or pain in the leg or arm. Very upset stomach or throwing up. Very bad belly pain. Very loose stools (diarrhea). For women, period changes. These include lots of bleeding, spotting, or bleeding between cycles. Weakness, numbness, or tingling. Change in strength on 1 side is greater than the other, trouble speaking or thinking, change in balance, or blurred eyesight. Sudden change in eyesight. Dark urine or yellow skin or eyes. Not able to eat. Any rash. Side effect or health problem is not better or you are feeling worse.
Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.
Store in a cool, dry place away from the reach of children. - Medicines must not be used past the expiry date.
Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
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