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MRP 151

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TAXIM OF TAB

Taxim OF Tablet
Uses and Benefits

Uses and Benefits

Taxim OF Tablet is a combination of 2 drugs which are used as antibiotics, which act against certain bacterial infections such as gonorrhea, pelvic inflammatory disease, urinary tract diseases, lower respiratory, soft tissue, uncomplicated genital infections, septicemia, and otitis externa etc, by preventing or inhibiting the growth of bacteria. However, the uses mentioned here are not exhaustive. There may be other conditions for which this medication may be used upon doctor’s discretion.

Composition

Composition

The active ingredients of Taxim OF Tablet are Cefixime 200mg and Ofloxacin 200mg.

Mechanism of Action of Drugs

Mechanism of Action of Cefotaxime:

Cefixime has bactericidal properties. It binds to penicillin-binding proteins present inside the bacterial cell wall and slows down the growth of bacterial cell wall synthesis resulting in bacterial cell death (bactericidal activity).

Ofloxacin is a quinolone antibiotic with bactericidal properties (kills bacteria). It helps to stop the growth of bacteria and thus treats bacterial infections.

Contraindications and Cautions

Contraindications and Caution

Patients with following conditions are suggested to seek advice from their health care professional before taking Taxim OF Tablet:

  • Hypersensitivity to any of the ingredients used in the Taxim OF Tablet such as Cefixime and other Cephalosporins, and Ofloxacin or any other quinolones
  • Caution:
  • Concurrent Nephrotoxic agent use
  • Seizure disorder
Side Effects

Side and Adverse Effects

The following side effects may or may not occur during the usage of Taxim OF Tablet. It is generally well tolerated when taken in the prescribed dosage guidelines. More common ones are generally mild and may include:

  • Diarrhea
  • Nausea
  • Vomiting
  • Abdominal pain
  • Loose stools
  • Dyspepsia
  • Flatulence
  • Anorexia
  • Pruritus Ani
  • Dryness of Mouth
  • Tendinitis
  • Rash
  • Vaginal discharge
  • Anemia
  • Ocular discomfort and irritation
  • Cough
  • Thirst weight loss

Rare but more serious adverse effects may include:

  • Dysuria
  • Pyuria
  • Anaphylaxis
  • Erythema multiforme
  • Steven-johnson syndrome
  • Toxic epidermal necrolysis
  • Acute renal failure
  • Anemia hemolytic
  • Blood dyscrasias
  • Superinfection
  • C. Difficile-associated diarrhea
  • Seizures
  • Respiratory arrest
  • Rhinorrhea
  • Photosensitivity reactions
  • Fatal Vasculitis
How to Use

How to Use

Do not exceed the dose prescribed by your doctor. Consume the tablet whole with a glass of water immediately after opening the tablet from the strip.
Do not break /chew/crush the Taxim OF tablet.

Avoid missing or forgetting a dose. If you do, take it as soon as you remember; but if it is almost time for your next dose, skip it and take it according to your normal schedule. Don’t consume two doses at the same time which is dangerous to your health.

Taxim OF tablet may be taken with or without food, preferably with food to avoid GI disturbances.
Take the dosage as recommended by your doctor.

Overdosage

Avoid taking more than the prescribed dosage. In case of an accidental overdose, promptly seek medical advice. Depending on the dosage, symptoms may vary but you may experience one or more of the following signs or symptoms:

  • GI Disturbances
  • Confusion
  • Dizziness
  • Impairment of consciousness
  • Convulsive seizures
Warnings and Precautions

Warnings and Precautions

Take the Taxim OF Tablet only on the advice of a medical practitioner. Dosage adjustment or complete avoidance of the medication may be required in the following conditions:

Pregnancy:

Cefixime: This drug may be used during pregnancy – the risk of fetal harm not expected. However, inform your doctor if you are pregnant or planning to become pregnant.
Ofloxacin: It is not known whether this drug may harm an infant or not. Therefore, inform your doctor if you are pregnant or planning to become pregnant.

Lactation:

Do not breastfeed a baby if you are taking this medicine because it is not known whether this drug may pass into breast milk or not.

Driving:

Do not drive or operate any machinery which needs your alertness because this may impair your thinking or reactions.

Food:

Delayed absorption of the drug in the presence of food.

Drug Interactions:

Caution always advised when used with other medicines especially cephalosporin antibiotics such as cefaclor, cefadroxil, Cefazolin, Cefdinir, Cefditoren, Cefpodoxime, Cefprozil, Ceftibuten, Cephalexin, Cephradine, theophylline, a diuretic or water pill, amiodarone, procainamide, sotalol and NSAIDs such as aspirin, ibuprofen, celecoxib, diclofenac, indomethacin, meloxicam and Antacids etc.

Precautions
  • Keep Taxim OF Tablet out of sight and reach of children.
  • Store this medicine away from heat, moisture, and light.
  • Do not use Taxim OF Tablet beyond its expiry.
  • Use the medicine for the full length of the prescribed course.
FDA Pregnancy Category

FDA Pregnancy Category

Category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


Drug Composition information
What is Cefixime for:

This medication is an oral cephalosporin (third generation) antibiotic, prescribed for gonorrhea, tonsillitis and pharyngitis. It works by fighting against the bacteria in the body.

How does Cefixime work:

Cefixime works to harm the bacteria and fight the infection.

How should Cefixime be used:

Adult: PO- Susceptible infections- The recommended dose is 200-400 mgday. Uncomplicated gonorrhoea- The recommended dose is 400 mg as a single dose. It comes as a tablet, capsule and syrup to take by mouth, with food.

Common side effects of Cefixime :

Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. - Loose stools (diarrhea). Yogurt or probiotics may help. You may get these products at health food stores or in some pharmacies. - For women, vaginal yeast infection. Report itching or discharge.

What do I do if I miss a dose

Take a missed dose as soon as you think about it. - If it is close to the time for your next dose, skip the missed dose and go back to your normal time. - Do not take 2 doses at the same time or extra doses. - Do not change the dose or stop this drug. - Talk with the doctor.

What precautions should I take when taking Cefixime :

If you have an allergy to cefixime or any other part of this drug. - Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.

When do I need to seek medical help

If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Very upset stomach or throwing up. Very loose stools (diarrhea), even after drug is stopped. Any bruising or bleeding. Any rash. Side effect or health problem is not better or you are feeling worse.

Can I take Cefixime with other medicines:

Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.

Are there any food restrictions

Avoid Alcohol

How do I store Cefixime :

Store it at room temperature and in an airtight container. Keep away from children.

Pregnancy Category

Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Therapeutic Classification

Cephalosporins

Seller Information
Manufactured By

ALKEM LABORATORIES LTD

alkem house,senapati bapat marg,lower parel,mumbai - 400013

Packed By

ALKEM LABORATORIES LTD

alkem house,senapati bapat marg,lower parel,mumbai - 400013

Applicable Offers

  • 20% Discount
    On prescription medicines, orders above Rs 1000 T & C
  • 10% Discount
    On prescription medicines, orders above Rs 200 T & C

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