This medication is an anticonvulsant, prescribed for the treatment of seizures and prevents migraine headaches, either alone or with other medications. It decreases abnormal excitement in the brain.
Topiramate may slow electrical activity in the brain. It works in the brain to ease pain.
It comes as a tablet, capsule, to take by mouth, with or without food twice a day in the morning and evening. When used alone, the starting dose is 25 mg night taken orally. The dose may be increased after 1 week to a maximum of 400 mgday. When used in combination, dose may be increased to a maximum of 800 mgday. It is also used to prevent migraine with a similar starting dose. It may be increased to 25 to 50 mg twice a day.
Feeling lightheaded, sleepy, having blurred eyesight, or a change in thinking clearly. Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how this drug affects you. Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing. Mood changes. Change in balance. Change in eyesight. Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. Feeling tired or weak. Weight loss. Acid balance changes.
Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.
If you have an allergy to topiramate or any other part of this drug. Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you are pregnant or may be pregnant.
If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Signs of low mood (depression), thoughts of killing yourself, nervousness, emotional ups and downs, thinking that is not normal, anxiety, or lack of interest in life. Change in thinking clearly and with logic. A fast heartbeat. Very bad dizziness or passing out. Not able to eat. Very upset stomach or throwing up. Feeling very tired or weak. Back pain, belly pain, or blood in the urine. May be signs of a kidney stone. Sudden change in eyesight, eye pain, or irritation. Not sweating during activities or in warm temperatures. Numbness or tingling in your hands or feet. A big weight loss. If seizures are worse or not the same after starting this drug. For women, if you get pregnant while taking this drug. Any rash. Side effect or health problem is not better or you are feeling worse.
Caution should be exercised in patients with history of liver or kidney problems, during pregnancy. It may cause drowsiness, dizziness, confusion, or trouble in concentration, avoid driving or operating machinery while taking this medication. Avoid activities such as swimming, driving, and climbing.
Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
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