This medication is a potassium-sparing diuretic, prescribed for hyperaldosteronism, low potassium levels, and for edema (fluid retention) caused by various conditions. It works by blocking the hormone aldosterone.
Spironolactone stops potassium loss. It lowers secretion from skin glands.
It comes as a tablet to take by mouth, with food. The recommended dose range is 50 to 400mgday for 3 to 4 weeks.
High potassium level. Signs include feeling weak, lightheaded, dizzy, feel like passing out, or have numbness or tingling. Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing. Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. Change in sex ability. This most often goes back to normal.
Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.
If you have an allergy to spironolactone or any other part of this drug. Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you have any of these health problems: High potassium levels or kidney disease.
If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Very bad dizziness or passing out. Signs of high potassium. Very upset stomach or throwing up. Very loose stools (diarrhea). For women, period changes. These include lots of bleeding, spotting, or bleeding between cycles. • For men, enlarged breasts. Any rash. Side effect or health problem is not better or you are feeling worse.
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
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