Country of origin: INDIA
Triglucored Forte tablet is a long-acting oral anti-diabetic medicine used alone or in combination with other medicines to treat type 2 diabetes mellitus. It helps in getting rid of extra glucose from the body through urine. This medicine is used with a proper healthy diet and exercise program to control high blood sugar in people with type 2 diabetes. Controlling high blood sugar level helps in preventing kidney damage, blindness, nerve problems and loss of limbs is lowered. However, the uses of the tablet mentioned here are not exhaustive. There may be other conditions for which this medication may be used upon doctor’s discretion.
The active ingredients of Triglucored Forte tablet are Glibenclamide (5MG), Metformin (500MG) and Pioglitazone (15MG)
Glibenclamide works by increasing the release of insulin from the pancreas and decreasing the hormones (glucagon) that raise blood glucose levels thereby reducing the fasting and post-meal sugar levels. Metformin reduces hepatic glucose production, decreases intestinal absorption of glucose and improves insulin sensitivity by increasing peripheral glucose uptake and utilization. Pioglitazone is a thiazolidinedione, that acts on a specific site that positively affects the production of substances that promote the breakdown of fats and glucose in the body and also decreases insulin resistance without causing any strain on pancreas. The combination is thus better effective in lowering blood glucose levels.
Patients with the following conditions are suggested to seek advice from their health care professionals before taking the Triglucored Forte tablet:
The following side effects may or may not occur during the usage of Triglucored Forte tablet. It is generally well tolerated when taken in the prescribed dose. You may experience one or more of the following common side effects:
Rare but more serious adverse effects may include:
Take Triglucored Forte tablet as instructed by your doctor. Swallow the tablet whole with water, immediately after opening it from the strip. Do not break or crush or chew the tablet.
Avoid missing or forgetting the dose. If you do, take it as soon as you remember; but if it’s almost time for your next dose, skip it and take it according to your normal schedule. Don’t swallow two doses at the same time which is dangerous to your health.
Triglucored Forte tablet should be taken with food, immediately or during breakfast or the first main meal of the day. Take the tablet at the same time every day as it helps to maintain a consistent level of medicine in the body.
Do not change the dose or stop taking the medicine before completion of the course or without consulting your doctor. Continue to use this drug until completion of the maximum amount suggested. This medicine is not recommended for children below 18 years of age.
Avoid taking Triglucored Forte tablet more than the prescribed dosage. In case of an accidental overdose of the medicine, promptly ask for medical advice. Depending on the dosage of the medicine, symptoms may vary in individuals, you may experience the following signs or symptoms:
Take the tablet only on the advice of a medical practitioner. Dosage adjustment or complete avoidance of the Triglucored Forte tablet may be required in the following conditions:
Among people with renal problems, caution is recommended. Close monitoring of kidney function and adjustments of dose of the medicine may be needed based on the clinical condition of the patient. If you have any, it is highly recommended that you consult your doctor before the consumption of this medicine.
Caution is advised among people with liver problems. Dose adjustments of the tablet may be needed based on the clinical condition of the patient. If you have any hepatic problems, it is highly recommended that you consult doctor before the consumption of this medicine.
Triglucored Forte tablet should be used with caution during pregnancy. Despite the fact that there are limited studies in human beings, animal studies have shown adverse effects on the developing baby. It is recommended that you consult your doctor before consuming this medicine.
There is no information regarding the presence of this medicine in human milk, or the breastfed infant, or the effects on milk production. However, inform your doctor if you are a nursing mother as it is still unknown if it causes harm to the foetus or not.
Consumption of alcohol with Triglucored Forte tablet is not recommended as it increases side effects of the tablet. If found any symptoms of extreme drowsiness, vomiting, confusion, report to your doctor immediately.
This medicine affects blood glucose levels and may decrease alertness, cause impaired judgement, affect your vision and make you feel dizzy, light headedness, confusion, so do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.
There are no known food interactions with this tablet.
Inform your doctor or pharmacist if you are taking any other medicines which includes over-the-counter drugs, herbal tonics, supplements and medicines that you buy without a prescription. Alert your doctor if you are taking Triglucored Forte tablet along with ACE inhibitors, sulfonylurea, dichlorphenamide, NSAIDs, cimetidine, trimethoprim, acetazolamide, propranolol, thiazides, iodinated contrast media, gatifloxacin, furosemide, miconazole
Category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
This medication contains sulfonylurea and biguanide antidiabetic combination, prescribed for type 2 diabetes.
Glyburide raises insulin levels and helps tissues respond better to the insulin. Metformin lowers sugar and helps insulin work better.
It comes as a tablet to take by mouth, with food. Adult: PO- Per tab contains glibenclamide 1.25 mg and metformin 250 mg. As initial therapy: Start with 1 tab 1-2 timesday. It may be increased if needed.
Low blood sugar. Signs include anger, shaking, a fast heartbeat, confusion, or sweating. Keep hard candies, glucose tablets, liquid glucose, or juice on hand for low blood sugar. Headache. Belly pain. Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. Loose stools (diarrhea). Bad taste in your mouth. This most often goes back to normal. Too much acid in the blood (lactic acidosis) may rarely happen.
Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses
If you have an allergy to glyburide, metformin, or any other part of this drug. Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you have a sulfa (sulfonamide) allergy, talk with your doctor. If you have any of these health problems: Acidic blood problem, drink too much alcohol, fluid loss, kidney disease, or liver disease. If you are having an x-ray with dye.
If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Very low blood sugar or very high blood sugar. Trouble breathing. Very bad dizziness. Very upset stomach or throwing up. Very loose stools (diarrhea). Very bad muscle pain or weakness. Feeling cold. Feeling very tired or weak. Dark urine or yellow skin or eyes. Very bad belly pain. Not able to eat. Any rash. Side effect or health problem is not better or you are feeling worse.
Store in a cool, dry place away from the reach of children. - Medicines must not be used past the expiry date.
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.
This tablet is a long-acting oral anti-diabetic medicine used alone or in combination with other medicines to treat type 2 diabetes mellitus. It helps in getting rid of extra glucose from the body through urine. This medicine is used with a proper healthy diet and exercise program to control high blood sugar in people with type 2 diabetes. Controlling high blood sugar level helps in preventing kidney damage, blindness, nerve problems and loss of limbs is lowered.
The medicine is well tolerated when taken in prescribed dosage guidelines. Common side effects such as hypoglycaemia, headache, dizziness, nausea, vomiting, blurred vision, constipation, peripheral oedema, metallic taste, chest discomfort, haemolytic anaemia, dyspnoea, abnormal stools, cholestatic jaundice are associated with the use of this medicine. Its use may also lead to extreme but uncommon side effects such as lactic acidosis, nasopharyngitis, upper respiratory tract infection, thrombocytopenia, swelling of face, lips, eyelids, tongue, hands and feet, congestive heart failure, bloody and cloudy urine, fracture of bones.
The tablet should be taken with food, immediately or during breakfast or the first main meal of the day.
If you ever had kidney, liver or heart disease, let your doctor know before taking this medicine. Inform your doctor about all the medicines you take to ensure that you are healthy. This medicine is contraindicated in patients with hypersensitivity to any of the active ingredients used in tablet or other sulfonylureas, severe renal or hepatic impairment, acute porphyria, stress related states (trauma, surgical procedures), intravascular administration of iodinated contrast agents, acute alcohol intoxication, type 1 diabetes, pregnancy. Caution is advised for patients with glucose, 6-phosphate dehydrogenase deficiency, stable heart failure, dehydration, diabetic ketoacidosis, debilitated and malnourished patients, postmenopausal or anovulatory females, prior history of active bladder cancer, prerenal azotaemia, children and elderly (>70 years), pregnancy and lactation.
The tablet affects blood glucose levels and may decreases alertness, cause impaired judgement, affect your vision and make you feel dizzy, light headedness, confusion, so do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.
The tablet is usually well tolerated when taken in the recommended dosage guidelines. Over dose of the medicine may lead to hypoglycaemia, dizziness, confusion, increased heartbeat, neurological impairment, sweating, lactic acidosis, muscle cramps, hypothermia, cholestatic liver injury.
The tablet should be used with caution during pregnancy. Despite the fact that there are limited studies in human beings, animal studies have shown no or low adverse effects on the developing baby. It is recommended that you consult your doctor before consuming this medicine.
No, do not take this medicine without doctor’s prescription.
Consumption of alcohol with this medicine is not recommended as it increases side effects of the tablet. If found any symptoms of extreme drowsiness, vomiting, confusion, report to your doctor immediately.
Store the medicine at room temperature (20-30 degree Celsius) in a cool and dry place. Keep the tablet according to the instructions mentioned on the pack or label. Store the medicine in the container or the pack it came in, tightly closed.
This tablet is designed to be swallowed with water. If you take them in a way they weren’t intended to be used, you could experience an overdose if the active constituent enters the blood stream too quickly. Alternatively, if it enters your body too slowly, it may never achieve a high enough concentration to be completely functional.
This medicine is not recommended for children below 18 years of age as the safety and efficacy of the tablet is not clinically established.
The amount of time for this medicine to show its effect in the body is approximately within one hour of administration.
The amount of time for which this medicine remains active in the body is for about 24 hours.
Medicines should always be taken under medical supervision. Take the medicine exactly as prescribed by your doctor: for dosage and duration. Most recommended dose is one tablet per day.
The number of days that any medicine must be taken varies from patient to patient; and case to case. So always stick to your doctor’s suggestion about how many days to take this medicine. It is important to keep your blood glucose levels under control as any fluctuations in your blood glucose levels may cause serious problems. So, do not stop taking the medicine before completion of the course or without consulting your doctor.
Use the medicine exactly as prescribed by your doctor for the dosage and duration.
Note: All of the above information is for reference purpose only. It is always recommended that you consult a medical professional.
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