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Country of origin: INDIA

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14 Units/pack

MRP 1181

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VYMADA 100MG TAB

Vymada 100MG tablet
Uses and Benefits

Uses and Benefits

Vymada 100MG tablet is a combination medicine used alone or in combination with other medicines for the prevention of cardiac symptoms in patients suffering from chronic heart failure and reduced ejection fraction. This medicine reduces the risk of hospitalization and death associated with heart failure in cardiac patients. It treats heart failure by relaxing the blood vessels and makes easier for heart to pump blood throughout the body. However, the uses mentioned here are not exhaustive. There may be other conditions for which the medication may be used upon your doctor’s discretion.

Composition

Composition

The active ingredients of Vymada 100MG tablet are Sacubitril 49MG and Valsartan 51MG

Mechanism of Action of Drugs

Mechanism of Action of Drugs

Sacubitril belongs to a class of angiotensin receptor neprilysin inhibitor (ANRI) that works by suppressing an enzyme called neprilysin, which degrades specific substances necessary for lowering the blood pressure in the body. Valsartan works by preventing the narrowing of blood vessels and facilitates smooth blood flow and also helps your body retain less water.

Contraindications and Cautions

Contraindications and Caution

Patients with following conditions are suggested to seek advice from their healthcare professionals before using Vymada 100MG tablet:

  • Hypersensitivity to any of the ingredients used in the tablet
  • Biliary cirrhosis
  • Cholestasis
  • Concomitant use with alsikiren in patients with diabetes mellitus or renal impairment
  • Severe hepatic impairment
  • Pregnancy
  • Caution:
  • Aortic or mitral stenosis
  • Severe congestive heart failure
  • Ascites due to cirrhosis
  • Primary hyperaldosteronism
  • Diabetes mellitus
  • Idiopathic or hereditary angioedema
  • Children
  • Lactation
Side Effects

Side and Adverse Effects

The following side effects may or may not occur during the usage of Vymada 100MG tablet. It is usually well tolerated when taken in the recommended dosage guidelines. You may experience one or more of the following symptoms:

  • Drowsiness
  • Stomach pain
  • Diarrhea
  • Nausea
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Altered levels of potassium in blood
  • Headache
  • Fainting
  • Cough
  • Weight gain
  • Increased thirst
  • Unusual weakness and tiredness
  • Vertigo

Rare but more serious adverse effects may include:

  • Acute renal failure
  • Hepatic injury
  • Angioedema
  • Azotaemia
  • Cardiac failure
How to Use

How to Use

Take Vymada 100MG tablet as instructed by your doctor. Swallow the tablet whole with water, immediately after opening it from the strip. Do not break or crush or chew the tablet.
Avoid missing or forgetting the dose. If you do, take it as soon as you remember; but if it’s almost time for your next dose, skip it and take it according to your normal schedule. Don’t swallow two doses at the same time which is dangerous to your health.
Vymada 100MG tablet may be taken with or without food. If significant stomach upset occurs, you could take it with food. Most recommended dose is one tablet per day. Take the tablet at the same time every day as it helps to maintain a consistent level of medicine in the body.
Do not change the dose or stop taking the medicine before completion of the course or without consulting your doctor. Continue to use this drug until completion of the maximum amount suggested even though the symptoms disappear after the medicine has begun.

Overdosage

Avoid taking medicine more than the prescribed dosage. If you notice any unusual or abnormal reactions after taking the tablet, promptly seek medical attention. Depending on the dosage of Vymada 100MG tablet, symptoms vary in individuals, you may experience one or more of the following symptoms:

  • Marked hypotension
  • Tachycardia or bradycardia
  • Depressed level of consciousness
  • Circulatory collapse
  • Cardiogenic shock
Warnings and Precautions

Warnings and Precautions

Use this tablet only on the advice of medical practitioner. Dose adjustments or complete avoidance of the Vymada 100MG tablet may be required in the following conditions:

Kidney:

Caution is advised among people with kidney problems. Close monitoring of kidney function and adjustments of dose of the medicine may be needed based on the clinical condition of the patient. If you have any renal problems, it is highly recommended that you consult doctor before the consumption of this tablet.

Liver:

Caution is advised among people with liver problems. Dose adjustments of the tablet may be needed. If you have any hepatic problems, it is highly recommended that you consult doctor before the consumption of this medicine. However, this medicine is not recommended in patients with severe liver diseases.

Pregnancy:

Vymada 100MG tablet might be risky to use during pregnancy as it is known to cause harm to the fetus. However, in some life-threatening situations, doctors may rarely prescribe if the benefits are more than the potential risks. It is recommended that you consult your doctor before consuming this medicine.

Lactation:

The medicine is likely unsafe to use for nursing mothers. Limited human data suggests that the medication may pass into the breastmilk and harm the infant. Consult your doctor immediately if the baby shows signs of increased sleepiness, breathing problems or difficulty in breast feeding.

Alcohol:

Consumption of alcohol with Vymada 100MG tablet is not recommended as it increases side effects and causes extreme drowsiness, dizziness, light headedness. Any symptoms of abnormal reactions after taking the tablet should be reported to your doctor immediately.

Driving:

The tablet may decrease alertness, cause impaired judgement, affect your vision and make you feel dizzy, light headedness, so do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

Food:

Potassium supplements (bananas, grape fruits) or potassium containing salt substitutes should be avoided while taking this medicine.

Drug Interactions:

All medicines interact differently for person to person. Inform your doctor or pharmacist if you are taking any other medicines which includes over-the-counter drugs, herbal tonics, supplements and medicines that you buy without a prescription. Alert your doctor if you are taking Vymada 100MG tablet with aliskiren, spironolactone, amiloride, heparin, ciclosporin, ritonavir, rifampicin, aspirin, ACE inhibitors, warfarin, dexamethasone.

Precautions
  • Do not use this tablet post the expiry date
  • Do not use this medication for durations longer than suggested by your doctor
  • Store at room temperature (20-30 degree Celsius)
FDA Pregnancy Category

FDA Pregnancy Category

Category D: There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


Drug Composition information
What is Valsartan for:

This medication is an angiotensin II receptor blocker, prescribed for hypertension, congestive heart failure and myocardial infarction (heart attack). It works by relaxing the blood vessels.

How does Valsartan work:

Valsartan lowers blood pressure by lowering a strong chemical in the body. It helps the heart work better.

How should Valsartan be used:

It comes as a tablet to take by mouth, with or without food. Adult: PO HTN Initial: 80 mg once daily, up to 160 mg once daily. Max: 320 mgday. Post-MI Initial: 20 mg twice daily, up to 160 mg bid if tolerated.

Common side effects of Valsartan :

High potassium level. Signs include feeling weak, lightheaded, dizzy, feel like passing out, or have numbness or tingling. Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing. Cough. Belly pain. Back pain. Loose stools (diarrhea). Feeling tired or weak. Kidney function that gets worse.

What do I do if I miss a dose

Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.

What precautions should I take when taking Valsartan :

If you have an allergy to valsartan or any other part of this drug. Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you have high blood sugar (diabetes) and are taking aliskiren. If you are pregnant or may be pregnant. If you are breast-feeding.

When do I need to seek medical help

If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Very bad dizziness or passing out. Very bad headache. Signs of high potassium. Cough that does not go away. Too much sweat, fluid loss, throwing up, or loose stools. May lead to low blood pressure. A big weight gain. Swelling in your legs or belly. For women, if you get pregnant while taking this drug. Any rash. Side effect or health problem is not better or you are feeling worse.

Can I take Valsartan with other medicines:

Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.

Are there any food restrictions

Avoid Alcohol

How do I store Valsartan :

Store it at room temperature (25°C), and in an airtight container. Keep away from children.

Pregnancy Category

Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Therapeutic Classification

Angiotensin II Antagonists


Frequently Asked Questions

Frequently Asked Questions
Q1. What is the use of the Vymada 100MG tablet?

The tablet is a combination medicine used alone or in combination with other medicines for the prevention of cardiac symptoms in patients suffering from chronic heart failure and reduced ejection fraction. This medicine reduces the risk of hospitalization and death associated with heart failure in cardiac patients. It treats heart failure by relaxing the blood vessels and makes easier for heart to pump blood throughout the body.

Q2. What are the side effects of the Vymada 100MG tablet?

The tablet is well tolerated when taken in prescribed dosage guidelines. Most common side effects include drowsiness, stomach pain, diarrhea, nausea, orthostatic hypotension (sudden lowering of blood pressure on standing), altered levels of potassium in blood, headache, fainting, cough, weight gain, increased thirst, unusual weakness and tiredness, vertigo. Its use may also lead to extreme but uncommon side effects such as acute renal failure, hepatic injury, angioedema, azotaemia, cardiac failure.

Q3. Should we take Vymada 100MG tablet with food or without food?

The tablet may be taken with or without food. If significant stomach upset occurs, you could take it with food.

Q4. What are the precautions to be followed while taking the Vymada 100MG tablet?

If you ever had impaired kidney function, sever liver impairment or heart disease, let your doctor know before taking this medicine. Inform your doctor about all the medicines you take to ensure that you are healthy. This medicine is contraindicated in patients with hypersensitivity to any of the ingredients used in the tablet, biliary cirrhosis, cholestasis, concomitant use with alsikiren in patients with diabetes mellitus or renal impairment, severe hepatic impairment, pregnancy. Caution is advised among patients with aortic or mitral stenosis, severe congestive heart failure, ascites due to cirrhosis, primary hyperaldosteronism, diabetes mellitus, idiopathic or hereditary angioedema, children, lactation.

Q5. Does Vymada 100MG tablet make you sleepy?

The tablet may decrease alertness, cause impaired judgement, affect your vision and make you feel dizzy, difficulty in concentration, fatigue, light headedness, so do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

Q6. Is Vymada 100MG tablet harmful? What does an overdose of Vymada 100MG tablet lead to?

The tablet is usually well tolerated when taken in the recommended dosage guidelines. Over dose of the medicine may lead to marked hypotension, tachycardia or bradycardia, depressed level of consciousness, circulatory collapse, cardiogenic shock.

Q7. Can I take Vymada 100MG tablet during pregnancy?

The tablet might be risky to use during pregnancy as it is known to cause harm to the fetus. However, in some life-threatening situations, doctors may rarely prescribe if the benefits are more than the potential risks. It is recommended that you consult your doctor before consuming this medicine.

Q8. Can Vymada 100MG tablet be taken without a doctor’s prescription?

No, do not take the medicine without doctor’s prescription.

Q9. Is it okay to drink alcohol while I am on the Vymada 100MG tablet?

Consumption of alcohol with this medicine is not recommended as it increases side effects such as difficulty in breathing, dizziness, light headedness. Any symptoms of abnormal reactions after taking the tablet should be reported to your doctor immediately.

Q10. How to store Vymada 100MG tablet?

Store the medicine at room temperature (20-30 degree Celsius) in a cool and dry place. Keep the tablet according to the instructions mentioned on the pack or label. Store the medicine in the container or the pack it came in, tightly closed.

Q11. If I have trouble swallowing Vymada 100MG tablet, can I mix it in water and drink it?

This tablet is designed to be swallowed with water. If you take them in a way they weren’t intended to be used, you could experience an overdose if the active constituent enters the blood stream too quickly. Alternatively, if it enters your body too slowly, it may never achieve a high enough concentration to be completely functional.

Q12. Can we give Vymada 100MG tablet to children?

This tablet is not recommended for children below 6 years of age since the safety and efficacy of use are not clinically established.

Q13. By when should I start seeing the results of the Vymada 100MG tablet?

The amount of time required for this medicine to show its action in the body is 2-4 hours after administration.

Q14. How long does the effect of Vymada 100MG tablet last?

The duration of time for which this medicine remains active in the body is for about 6-8 hours.

Q15. Can we take Vymada 100MG tablet daily? If yes, how many tablets can we take everyday?

Medicines should always be taken under medical supervision. Take the medicine exactly as prescribed by your doctor: for dosage and duration. Most recommended dose is one tablet per day.

Q16. For how many days should I take the Vymada 100MG tablet?

The number of days that any medicine must be taken varies from patient to patient; and case to case. So always stick to your doctor’s suggestion about how many days to take this medicine.

Q17. When should I take Vymada 100MG tablet?

Use the medicine exactly as prescribed by your doctor for the dosage and duration.

Note: All of the above information is for reference purpose only. It is always recommended that you consult a medical professional.

Seller Information
Manufactured By

NOVARTIS HEALTHCARE PVT LTD

gala -1a & 2a, bldg 28, arihant compound, kopar, purna, tal-bhiwandi, dist-thane 421302, india

Packed By

NOVARTIS HEALTHCARE PVT LTD

gala -1a & 2a, bldg 28, arihant compound, kopar, purna, tal-bhiwandi, dist-thane 421302, india

Applicable Offers

  • 20% Discount
    On prescription medicines, orders above Rs 1000 T & C
  • 10% Discount
    On prescription medicines, orders above Rs 200 T & C

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