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Country of origin: INDIA

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10 Units/pack

MRP 174

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ZAPTRA 12.5MG CAP

ZAPTRA 12.5MG CAP
Uses and Benefits

Uses and Benefits

Zaptra 12.5Mg capsule is a combination prescription medicine used to treat depression, anxiety disorders, panic attacks, post-traumatic stress disorder, obsessive compulsive disorder and sleep disorders by decreasing the abnormal and excessive activity of the nerve cells. The capsule can also decrease the feelings of tiredness, restlessness, difficulty concentrating, feeling irritable and sleep problems that often come with anxiety disorder. However, the uses mentioned here are not comprehensive, there may be other conditions for which the medication may be used upon your doctor’s discretion.

Composition

Composition

The active ingredients of Zaptra 12.5Mg capsule are Paroxetine (12.5Mg) and Clonazepam (0.5Mg)

Mechanism of Action of Drugs

Mechanism of Action of Drugs

Zaptra capsule has mood enhancing and anxiety lowering effects. Paroxetine is a selective serotonin reuptake inhibitor, that raises serotonin levels, a chemical messenger that enhances mood. Clonazepam is a benzodiazepine which works by increasing the action of a chemical messenger known as GABA by supressing the abnormal and excessive activity of the nerve cells in the brain.

Contraindications and Cautions

Contraindications and Caution

Patients with following conditions are suggested to seek advice from their healthcare professionals before using Zaptra 12.5Mg capsule.

  • Hypersensitivity to any of the ingredients used in the capsule formulation.
  • Severe respiratory insufficiency
  • Concomitant use of monoamine oxidase inhibitors, pimozide, thioridazine
  • Sleep apnoea syndrome
  • Pregnancy and lactation

Caution:

  • Narrow angle glaucoma
  • Cardiovascular diseases
  • Bipolar disorders
  • Diabetes mellitus
  • History of bleeding disorders
  • Bone fractures
  • Seizure disorders
  • Depression or suicide thinking and behaviour
  • Renal and hepatic impairment
Side Effects

Side and Adverse Effects

The following side effects may or may not occur during the usage of Zaptra 12.5Mg capsule. It is usually well tolerated when taken in the recommended dosage guidelines. More common side effects include:

  • Diarrhea
  • Constipation
  • Gastritis
  • Dry mouth
  • Fatigue
  • Headache
  • Tremors
  • Muscular hypotonia
  • Behavioural disturbances like aggressiveness, agitation
  • Increased or decreased appetite
  • Nausea
  • Dyspepsia
  • Bleeding abnormalities
  • Sexual disorders
  • Rare but more serious effects may include:
  • Arthralgia
  • Depression
  • Bradycardia
  • Insomnia
  • Coordination disturbances
  • Dizziness
  • Anorexia
  • Angioedema
  • Hyponatraemia
How to Use

How to Use

Take Zaptra 12.5Mg capsule as instructed by your doctor. Do not use this medicine for durations shorter or longer than suggested by your doctor as it has a very high potential of becoming habit-forming. Avoid missing or forgetting the dose, if you do, take the Zaptra 12.5Mg capsule as soon as remember, however if its almost time for your next dose, skip the previous dose and take it according to your normal scheduled time.
Continue to use this drug until completion of the maximum amount suggested and should not stop taking it suddenly. Zaptra 12.5Mg capsule should be taken with food to avoid stomach upset.

Overdosage

Avoid taking medicine more than the prescribed dosage. If you notice any unusual or abnormal reactions after taking the capsule, promptly seek medical attention. Depending on the dosage of Zaptra 12.5Mg capsule, symptoms vary in individuals, you may experience one or more of the following symptoms:

  • Somnolence
  • Dizziness
  • Nausea
  • Tremor
  • Tachycardia
  • Confusion
  • Vomiting
  • Fever
  • Hypertension, hypotension
  • Aggressiveness
  • Urinary retention
  • Rhabdomyolysis
  • Gastrointestinal haemorrhage
Warnings and Precautions

Warnings and Precautions

Use this capsule only on the advice of medical practitioner. Dose adjustments or complete avoidance of the Zaptra 12.5Mg capsule may be required in the following conditions:

Kidney:

ution is advised among people with kidney problems. Close monitoring of kidney function and adjustments of dose of the medicine may be needed based on the clinical condition of the patient. If you have any renal problems, it is highly recommended that you consult doctor before the consumption of this capsule.

Liver:

Caution is advised among people with liver problems. Dose adjustments of the Zaptra 12.5Mg capsule may be needed. If you have any hepatic problems, it is highly recommended that you consult doctor before the consumption of this medicine. However, use of this medicine is not suggested in patients with moderate to severe liver diseases. Any symptoms such as nausea, fever, dark urine etc should be reported to your doctor immediately.

Pregnancy:

Zaptra 12.5Mg capsule might be risky to use during pregnancy as it is known to cause harm to the fetus. Infants born to mothers who used this medication while pregnant may show withdrawal symptoms. It is recommended that you consult your doctor before consuming this medicine.

Lactation:

The medicine is likely unsafe to use for nursing mothers. Limited human data suggests that the medication may pass into the breastmilk and harm the infant. Consult your doctor immediately if the baby shows signs of increased sleepiness, breathing problems or difficulty in breast feeding.

Alcohol:

Consumption of alcohol with Zaptra 12.5Mg capsule is not recommended as it increases side effects such as difficulty in breathing, dizziness, light headedness. Any symptoms of abnormal reactions after taking the capsule should be reported to your doctor immediately.

Driving:

This medicine may decrease alertness, cause impaired judgement, affect your vision and make you feel dizzy, light headedness, so do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

Food:

Foods containing caffeine, tea, chocolates should be avoided as they stimulate your brain while Zaptra 12.5 Mg calms the brain.

Drug Interactions:

Alert your doctor if you are taking Zaptra 12.5Mg capsule with any of the below medicines:
Increased risk of bleeding: Aspirin, Anticoagulants such as Warfarin
Pimozide
Atenolol, Metoprolol
Phenothiazines: Perphenazine
Cimetidine
Diuretics
Monoamine oxidase inhibitors: Rasagiline, linezolid, methylene blue
Anti-psychotics: Clozapine
Tricyclic antidepressants: Clomipramine, nortriptyline, desipramine
Anxiolytics
Inform your doctor or pharmacist if you are taking any other medicines which includes over-the-counter drugs, herbal tonics, supplements and medicines that you buy without a prescription.

Precautions
  • Do not use this capsule post the expiry date
  • Do not use this medication for durations longer than suggested by your doctor
  • Store at room temperature (20-30 degree Celsius)
FDA Pregnancy Category

FDA Pregnancy Category

Category D: There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may sometimes warrant use of the drug in pregnant women despite potential risks.


Drug Composition information
What is Clonazepam for:

This medication is an anticonvulsant, muscle relaxant, prescribed for Lennox-Gastaut syndrome, panic disorder and seizures. It decreases abnormal electrical activity in the brain.

How does Clonazepam work:

Clonazepam calms the brain.

How should Clonazepam be used:

Seizure Disorders- Adults: The initial dose should not exceed 1.5 mgday divided into three doses. It may be increased if needed. Pediatric Patients: The initial dose should be between 0.01 and 0.03 mgkgday but not to exceed 0.05 mgkgday given in two or three divided doses. Panic Disorder- Adults: The initial is 0.25 mg two times per day. It may be increased if needed. It comes as a tablet to take by mouth as directed by your physician.

Common side effects of Clonazepam :

Feeling lightheaded, sleepy, having blurred eyesight, or a change in thinking clearly. Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how this drug affects you. Dry mouth. Good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. See a dentist often. Feeling tired or weak. Change in balance

What do I do if I miss a dose

Take a missed dose as soon as you think about it. - If it is close to the time for your next dose, skip the missed dose and go back to your normal time. - Do not take 2 doses at the same time or extra doses. - Do not change the dose or stop this drug. - Talk with the doctor.

What precautions should I take when taking Clonazepam :

Alert your doctor if you are pregnant or if you become pregnant while being treated with Clonazepam. Use an appropriate birth control method while being treated with Clonazepam. You may wish to discuss birth control options with your doctor. - Alert your doctor if you are breastfeeding. Do not breastfeed while being treated with Clonazepam. - Alert your doctor if you have an eye disease known as glaucoma, liver disease or myasthenia gravis.

When do I need to seek medical help

If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Signs of low mood (depression), thoughts of killing yourself, nervousness, emotional ups and downs, thinking that is not normal, anxiety, or lack of interest in life. Big change in balance. Change in thinking clearly and with logic. Feeling very tired or weak. If seizures are worse or not the same after starting this drug. Any rash. Side effect or health problem is not better or you are feeling worse.

Can I take Clonazepam with other medicines:

Alert your doctor if you are taking any other medicines, especially those listed here: - gastric medicine such as cimetidine - asthma medicine such as theophylline. - antifungals or antibiotics such as doxycycline, erythromycin, itraconazole - birth control pills - other epilepsy medicines. - sleeping pills. - heart or blood pressure medicines such as verapamil. - other medicines such as buprenorphine, disulfiram. Always inform your doctor and pharmacist if you are taking any other medicines, including herbal tonics, supplements and medicines that you buy without a prescription.

Are there any food restrictions

Avoid Alcohol

How do I store Clonazepam :

Store it at room temperature and away from light.

Pregnancy Category

Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Therapeutic Classification

Anticonvulsants, Anxiolytics , Hypnotics & Sedatives


Frequently Asked Questions

Frequently Asked Questions

What is the use of Zaptra 12.5Mg Capsule?
Zaptra 12.5Mg capsule is a combination prescription medicine used to treat depression, anxiety disorders, panic attacks, post-traumatic stress disorder, obsessive compulsive disorder and sleep disorders by decreasing the abnormal and excessive activity of the nerve cells. The capsule can also decrease the feelings of tiredness, restlessness, difficulty concentrating, feeling irritable and sleep problems that often come with anxiety disorder.
Can we take this medicine daily?
Take the medicine exactly as prescribed by your doctor for the dosage and duration.
How many Zaptra 12.5Mg capsules can be taken in a day?
Take the medicine exactly as prescribed by your doctor for the dosage and duration. Most recommended dose is one capsule per day.
What are the side effects of this medicine?
The capsule is well tolerated when taken in prescribed dosage guidelines. Most common side effects include diarrhea, constipation, gastritis, dry mouth, fatigue, headache, dizziness, tremors, muscular hypotonia, behavioural disturbances like aggressiveness, agitation, nausea, dyspepsia, bleeding abnormalities, sexual disorders. Its use may also lead to extreme but uncommon side effects such as arthralgia, depression, bradycardia, insomnia, coordination disturbances, anorexia, angioedema, hyponatraemia.

Does this medication make you sleepy?
Zaptra 12.5Mg capsule may decrease alertness, cause impaired judgement, affect your vision and make you feel dizzy, difficulty in concentration, fatigue, light headedness, so do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

When should I take the medicine?
Use the medicine exactly as advised by your doctor for the dosage and duration.

Is this medicine harmful for health?
Zaptra 12.5Mg capsule is usually well tolerated when taken in the recommended dosage guidelines. Over dose of the medicine may lead to somnolence, dizziness, nausea, tachycardia, confusion, vomiting, fever, hypertension, hypotension, aggressiveness, urinary retention, rhabdomyolysis, gastrointestinal haemorrhage.

Can we take this on empty stomach or should take it with food?
Take the capsule with or without food. If significant stomach upset occurs, you could take with food.

What are the precautions I need to follow while taking the Zaptra 12.5Mg capsule?
If you ever had impaired kidney function, sever liver impairment or heart disease, let your doctor know before taking this medicine. Inform your doctor about all the medicines you take to ensure that you are healthy. Caution is advised for people with severe respiratory insufficiency, concomitant use of monoamine oxidase inhibitors, pimozide, thioridazine, sleep apnoea syndrome, pregnancy and lactation, narrow angle glaucoma, cardiovascular diseases, bipolar disorders, diabetes mellitus, history of bleeding disorders, bone fractures, seizure disorders, depression or suicide thinking and behaviour, renal and hepatic impairment.
Can I give this medicine to a child?
This capsule is not recommended for children below 18 years of age since the safety and efficacy of use are not clinically established.

How long does the effect of medicine last?
The duration required for the capsule to show its effect in the body depends in the intended use and the clinical condition of the patient.

Can I take this medicine during pregnancy?
Zaptra 12.5Mg capsule might be risky to use during pregnancy as it is known to cause harm to the fetus. Infants born to mothers who used this medication while pregnant may show withdrawal symptoms. It is recommended that you consult your doctor before consuming this medicine.

At what time can I take the medicine?
To get the most benefits, take the medicine preferably at the same time every day and dosing interval must be at least 18 hours between two doses.

Can I take this capsule without a doctor’s prescription?
No, do not take the medicine without doctor’s prescription.

Is it okay to drink alcohol while I am using this medicine?
Consumption of alcohol with Zaptra 12.5Mg capsule is not recommended as it increases side effects such as difficulty in breathing, dizziness, light headedness. Any symptoms of abnormal reactions after taking the capsule should be reported to your doctor immediately.

How to store the medicine?
Store the medicine at room temperature (15-30 degree Celsius) in a cool and dry place. Keep the capsule according to the instructions mentioned on the pack or label. Store the medicine in the container or the pack it came in, tightly closed.

If I have trouble swallowing this capsule, can I mix it in water and drink?
Zaptra 12.5Mg capsule is designed to be swallowed with water. If you take them in a way they weren’t intended to be used, you could experience an overdose if the active constituent enters the blood stream too quickly. Alternatively, if it enters your body too slowly, it may never achieve a high enough concentration to be completely functional.

For how long should I take the medicine?
Take the medicine as prescribed by your doctor. Do not stop taking the medicine before completion of the course or without consulting your doctor.

By when should I start seeing results of the medicine?
The duration required for this medicine to show its action in the body is not clinically established. It may take several weeks to see the full benefits of the medicine, although few people may start to feel better sooner.

What are the alternate medicines to Zaptra 12.5Mg capsule?
Pexep Plus 12.5Mg Capsule
Panazep 12.5Mg Capsule
Paxit CR Plus Capsule
Xet CR Plus 12.5Mg Capsule
Parazep 12.5Mg Capsule

Note: All the above information is for reference purpose only. It is always recommended that you consult a medical professional to be sure.

Seller Information
Manufactured By

INTAS PHARMACEUTICALS LTD

bhagey khola,rangpo,east sikkim-737132,india

Packed By

INTAS PHARMACEUTICALS LTD

bhagey khola,rangpo,east sikkim-737132,india

Applicable Offers

  • 20% Discount
    On prescription medicines, orders above Rs 1000 T & C
  • 10% Discount
    On prescription medicines, orders above Rs 200 T & C

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