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      Mfg/Mkt: intas pharmaceuticals ltd

      ZAVAMET 50/500MG TAB

      Country of origin: INDIA

      Seller Information

      10 Units/pack

      MRP 101.50

      Inclusive of all Taxes

      FLAT 20% OFF On bills above 1000.0
      ZAVAMET 50/500MG TAB

      Zavamet 50/500Mg Tab
      Uses and Benefits

      Uses and Benefits

      Zavamet 50/500mg tablet is used in the treatment of Type 2 diabetes mellitus. It is used with proper healthy diet and exercise program to control high blood sugar in type 2 diabetic patients. Controlling high blood sugar level helps prevents kidney damage, blindness, nerve problems, loss of limbs and sexual function problems. This tablet is also used in treating polycystic ovarian syndrome. However, the uses mentioned are not exhaustive, there may be other conditions for which this tablet may be used upon doctor’s discretion.

      Composition

      Composition

      Zavamet tablet is a combination of two drugs namely vildagliptin (50mg) and metformin (500mg).

      Mechanism of Action of Drugs

      Mechanism of Action of Drugs

      Vildagliptin increases the release of insulin from pancreas and reduces the hormones that raise blood sugar levels. This increases the fasting and post meal sugar levels.

      Metformin reduces hepatic glucose production, decreases intestinal absorption of glucose and improves insulin sensitivity by increasing peripheral glucose uptake and utilization.

      Contraindications and Cautions

      Contraindications and Caution

      Patients with following conditions are suggested to seek advice from their healthcare professionals before taking Zavamet 50/500 tablet.

      • Hypersensitivity to any of the ingredients used in Zavamet tablet formulation
      • Metabolic acidosis
      • Sever renal impairment
      • Caution:
      • Type 1 diabetes
      • Vitamin B12 deficiency
      • Diabetic ketoacidosis
      • Liver impairment
      • Hypoglycemia
      • Pancreatitis
      Side Effects

      Side and Adverse Effects

      The following side effects may or may not occur during the usage of Zavamet tablet. It is usually well tolerated when taken in prescribed dosage guidelines. Most common side effects include

      • Dizziness
      • Headache
      • Hyperhidrosis
      • Nausea
      • Tremors
      • Chills
      • Gastroesophageal reflux

      Rare but more serious adverse effects may include:

      • Arthralgia
      • Diarrhea
      • Fatigue
      • Flatulence
      • Hypoglycemia
      • Peripheral oedema
      • Nasopharyngitis
      • Backache

      Though extremely rare, you may develop lactic acidosis, a dangerous buildup of lactic acid in your blood

      How to Use

      How to Use

      Zavamet should be taken with meals to reduce stomach discomfort. If you have been prescribed to take one dose each day, take it in the morning. If u have been prescribed to take two doses each day take one in the morning and one in the evening. Do not crush or chew the tablet

      If u miss a dose, take the missed dose as soon as u remember, if it is almost time for your next dose, take only the usual dose. Do not double your dose to make up for the missed dose.

      The dose of the tablet you are given will usually depend on your condition, blood sugar levels and other medicines you are taking.

      Overdosage

      Avoid taking Zavamet 50/500mg tablet more than the prescribed dosage. In case of accidental overdose, kindly consult your doctor. Based on the dosage, symptoms vary from individual to individual. It is possible that you may experience one or more of the following symptoms:

      • Rash
      • Itching
      • Heart palpitations
      • Shortness of breadth
      • Swelling of face lips tongue or throat
      Warnings and Precautions

      Warnings and Precautions

      Take Zavamet 500 Tablet only on the advice of medical practitioner. Adjustments of dosage or complete avoidance of the medicine may be required in the following conditions:

      Kidney:

      Among people with renal problems, caution is recommended. Dose adjustments may be needed. If you have any renal problems, it is highly recommended that you consult your doctor before the consumption of this medicine

      Liver:

      Caution is advised among people with hepatic problems. Dose adjustments may be needed. If you have any hepatic problems, it is highly recommended that you consult your doctor before the consumption of this medicine

      Pregnancy:

      Consult your doctor if you’re pregnant or planning to become pregnant. Zavamet 50/500mg tablet should only be used in pregnancy if clearly needed. It is important for women with type 2 diabetes to treat their condition even during pregnancy.

      Lactation:

      There is no information regarding the presence of this medicine in human milk, or the breastfed infant, or the effects on milk production. However, inform your doctor if you are a breast feeding as it is still unknown if it causes harm to the fetus or not.

      Alcohol:

      Alcohol can increase your risk of lactic acidosis from metformin. Alcohol may also raise or lower your blood sugar levels. Do not drink alcohol while taking this drug.

      Driving:

      Your ability to drive may be affected if your blood sugar is too low or too high. Since Zavamet 50/500mg tablet may decrease alertness, affect your vision or make you feel dizzy, do not drive, operate heavy machinery or involve in any works which may demand your attention or physical strength.

      Food:

      There are no known food interactions with Zavamet 50/500mg tablet.

      Drug Interactions:

      Alert your doctor if you are taking any of the below medications

      • Blood pressure drugs include: Furosemide, hydrochlorothiazide
      • Cholesterol drug: nicotinic acid
      • Glaucoma drugs: acetazolamide, brinzolamide
      • Topiramate
      • Phenytoin
      • Phenothiazines
      • Thyroid drugs: desiccated thyroid, levothyroxine, liothyronine

      Always inform your doctor or pharmacist if you are taking any other medicines which includes herbal tonics, supplements and medicines that you buy without a prescription.

      Precautions
      • Store at temperature between 15-30 degrees Celsius.
      • Keep the tablet out of reach of children away from moisture and light
      FDA Pregnancy Category

      FDA Pregnancy Category

      Category B: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.


      Drug Composition information
      What is Metformin for:

      This medication is an oral antidiabetic agent, prescribed for type 2 diabetes. It helps control blood sugar levels.

      How does Metformin work:

      Metformin lowers sugar and helps insulin work better.

      How should Metformin be used:

      Take Metformin exactly as directed by your doctor. Do not take more or less than instructed by your doctor. - Metformin must be taken regularly for it to work well. Do not stop taking it unless instructed by your doctor. - Metformin must be taken with food. - If you are taking an extended-release type of Metformin, swallow the tablet whole with food. Do not crush or chew the tablet.

      Common side effects of Metformin :

      Low blood sugar signs include, anger, shaking, a fast heartbeat, confusion, or sweating. Keep hard candies, glucose tablets, liquid glucose, or juice on hand for low blood sugar. - Belly pain. - Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. - Loose stools (diarrhea). - Not hungry. - Bad taste in your mouth. This most often goes back to normal. - Too much acid in the blood (lactic acidosis) may rarely happen.

      What do I do if I miss a dose

      Take a missed dose as soon as you think about it. - If it is close to the time for your next dose, skip the missed dose and go back to your normal time. - Do not take 2 doses at the same time or extra doses. - Do not change the dose or stop this drug. Talk with the doctor.

      What precautions should I take when taking Metformin :

      Metformin may not be suitable for you if you suffer from heart, liver, kidney, adrenal or pituitary disease. - Alert your doctor if you are pregnant or breastfeeding. - If you are going for an operation, dental work or any X-ray procedure in which a dye is injected, inform your doctor or dentist that you are taking Metformin. - You may need to stop taking Metformin before the procedure and wait 48 hours to restart your medicine.

      When do I need to seek medical help

      If you think there was an overdose, call your local poison control center or ER right away. - Signs of a very bad reaction to the drug. - These include wheezing, chest tightness, fever, itching, bad cough, blue or gray skin color, seizures, or swelling of face, lips, tongue, or throat. - Very low blood sugar or very high blood sugar. - Very bad dizziness. - Trouble breathing. - Feeling cold. - Very bad belly pain. - Very upset stomach or throwing up. - Very loose stools (diarrhea). - A big weight loss. - Very bad muscle pain or weakness. - Feeling very tired or weak. - Any rash. - Side effect or health problem is not better or you are feeling worse

      Can I take Metformin with other medicines:

      A type of heart medicine called beta-blockers may mask the symptoms of hypoglycaemia when taken with Metformin. Some examples of beta-blockers are metoprolol, atenolol and propranolol. - Inform your doctor if you are taking diuretics (medicines to remove excess water) such as hydrochlorothiazide; a group of heart medicine such as captopril or enalapril; a type of gastric medicine called cimetidine or birth control pills. - Always inform your doctor and pharmacist if you are taking any other medicines, including herbal tonics, supplements and medicines that you buy without a prescription.

      Are there any food restrictions

      It is important for you to maintain a healthy diet and weight in order to help keep your diabetes under control. - Avoid alcohol.

      How do I store Metformin :

      Store in a cool, dry place away from the reach of children. - Medicines must not be used past the expiry date.

      Pregnancy Category

      Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

      Therapeutic Classification

      Antidiabetic Agents


      Frequently Asked Questions

      Frequently Asked Questions

      What is the use of Zavamet 50/500mg tablet?

      Zavamet 50/500mg tablet is used in the treatment of Type 2 diabetes mellitus. It is used with proper healthy diet and exercise program to control high blood sugar in type 2 diabetic patients. Controlling high blood sugar level helps prevents kidney damage, blindness, nerve problems, loss of limbs and sexual function problems.

      What are the side effects of this medicine?

      Common side effects such as Nausea, dizziness, headache, tremors, chills, gastroesophageal reflux, arthralgia, diarrhea, fatigue, hypoglycemia, peripheral oedema, nasopharyngitis, backache.

      Does this medication make you sleepy?

      Since consuming this medicine effects blood glucose level, do not operate heavy machinery or involve in any works which may demand your attention or physical strength.

      When should I take the medicine?

      Take the medicine exactly as prescribed by your doctor for the dosage and duration.

      Can we take this on empty stomach or should take it with food?

      Take the tablet twice daily with food to reduce stomach discomfort.

      What are the precautions I need to follow while taking the Zavamet 50/500mg tablet?

      If you ever had kidney, liver or heart disease, let your doctor know before taking this medicine. Inform your doctor about all the medicines you take to ensure that you are healthy. Caution is advised for people with Vitamin B12 deficiency, liver impairment, pancreatitis and diabetic keto acidosis.

      Can I give this medicine to a child?

      This medicine is not recommended for patients below 18 years of age as safety and efficacy in children is not established.

      How long does the effect of medicine last?

      The amount of time for which this medicine remains active in the body is not clinically established.

      Can I take Zavamet 50/500mg tablet during pregnancy?

      Do not take this medicine if you are pregnant or planning to get pregnant because safety during pregnancy is not yet established. Consult your doctor about the best way to control your blood sugar.

      At what time can I take the medicine?

      To get the most benefits, take the medicine with food, preferably at the same time every day and you should not quit unless your doctor suggests.

      Can I take the Zavamet 50/500mg tablet without a doctor’s prescription?

      No, do not take this medicine without doctor’s prescription.

      Is it okay to drink alcohol while I am taking this medicine?

      Do not take this medicine along with alcohol beverages as it may cause severe hepatic problems.

      How to store the medicine? 

      Store the medicine at room temperature (15-30 degree Celsius)

      For how long should I take the medicine?

      Take the medicine as prescribed by your doctor. Do not stop taking the medicine before completion of the course or without consulting your doctor.

      By when should I start seeing results of the medicine?

      Within 1-3 hours of administration, the effect of the medicine can be observed.

      What are the alternate medicines to Zavamet 50/500mg tablet?

      Galvusmet 50/500mgTablet

      Intaglip M Tablet

      Vysov M 50/500mg Tablet

      Note: All the above information is for reference purpose only. It is always recommended that you consult a medical professional to be sure.

      Seller Information
      Manufactured By

      INTAS PHARMACEUTICALS LTD

      bhagey khola, rangpo, east sikkim - 737132, india

      Packed By

      INTAS PHARMACEUTICALS LTD

      bhagey khola, rangpo, east sikkim - 737132, india

      Applicable Offers

      • 20% Discount
        On prescription medicines, orders above Rs 1000 T & C

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