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Country of origin: INDIA

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10 Units/pack

MRP 157

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Zifi CV Tablet 100mg
Uses and Benefits

Uses and Benefits

Zifi CV tablet 100mg is an antibiotic medicine. This tablet acts against certain bacterial infections of the ear, nose, lungs, sinus, skin and urinary tract by preventing or inhibiting the growth of bacteria. However, the uses mentioned here are not exhaustive. There may be other conditions for which this medication may be used upon doctors discretion.



The active ingredients of Zifi CV tablet 100mg are Cefixime 100mg and Clavulanic Acid 62.5mg.

Mechanism of Action of Drugs

Mechanism of Action of Drugs

With its bactericidal properties, Cefixime binds to penicillin-binding proteins located inside the bacterial cell wall and slows down the growth of bacterial cell wall synthesis. Thus resulting in bacterial cell death (bactericidal activity).

Clavulanic Acid inhibits cell wall mucopeptide synthesis. In addition to this, it also inhibits the beta-lactamases, which are the enzymes produced by bacteria that provide multi-resistance to beta-lactam antibiotics – thus showing its bacteriocidal property.

Contraindications and Cautions

Contraindications and Caution

Patients with the following conditions are suggested to seek advice from their health care professionals before taking Zifi CV tablet 100mg:

  • Hypersenstivity to any of the ingredients used in the Zifi CV tablet 100mg such as Cefixime or other Cephalosporins, and Clavulanic Acid
  • Anaphylactic reactions to beta-lactams
  • History of Cholestatic Jaundice/hepatic dysfunction associated with associated with Amoxicillin and Clavulanic acid therapy


  • Concurrent Nephrotoxic agent use
  • Seizure disorder
Side Effects

Side and Adverse Effects

The following side effects may or may not occur during the usage of Zifi CV tablet 100mg. It is generally well tolerated when taken in the prescribed dosage guidelines. More common ones are generally mild and may include:

  • Diarrhea
  • Nausea
  • Vomiting
  • Abdominal pain
  • Loose stools
  • Dyspepsia
  • Flatulence
  • Anorexia
  • Pruritus Ani
  • Dryness of Mouth
  • Rash
  • Urticaria
  • Epigastric discomfort
  • Glossitis
  • Stomatitis
  • Black hairy tongue
  • Candidiasis, oral or Vulvovaginal
  • LFTs Elevated

Rare but more serious adverse effects may include:

  • Dysuria
  • Pyuria
  • Anaphylaxis
  • Erythema multiforme
  • Steven-johnson syndrome
  • Toxic epidermal necrolysis
  • Acute renal failure
  • Anemia hemolytic
  • Blood dyscrasias
  • Superinfection
  • C. Difficile-associated diarrhea
  • Seizures
  • Serum sickness-like reaction
  • Exfoliative dermatitis
  • Superinfection
  • Agranulocytosis
  • Interstitial nephritis
  • Hepatitis
  • Cholestatic jaundice
  • Seizures
How to Use

How to Use

Do not exceed the dose prescribed by your doctor.
Consume the Zifi CV tablet 100mg whole with a glass of water immediately after opening the tablet from the strip. Do not break /chew/cut the tablet whole.
Avoid missing or forgetting a dose. If you do, take it as soon as you remember; but if it is time for your next dose, skip it and take it according to your normal schedule. Don’t consume two doses at the same time which is dangerous to your health.
This medicine may be taken with or without food, preferably with food to avoid GI disturbances.
Take the dosage as recommended by your doctor.


Avoid taking more than the prescribed dosage. In case of an accidental overdose, promptly seek medical advice. Depending on the dosage, symptoms may vary but you may experience one or more of the following signs or symptoms:

  • GI Disturbances
  • Fluid and Electrolyte Imbalance
  • Crystalluria and interstitial nephritis may lead to renal failure
Warnings and Precautions

Warnings and Precautions

Take the tablet only on the advice of a medical practitioner. Dosage adjustment or complete avoidance of the medication may be required in the following conditions:


Cefixime: This drug may be used during pregnancy – the risk of fetal harm is not seen. However, inform your doctor if you are pregnant or planning to become pregnant.
Clavulanic Acid: Do not use this drug until unless suggested by your doctor. Make sure you inform your doctor if you are pregnant or planning to become pregnant.


Cefixime: Do not breastfeed a baby if you are taking this medicine because it is not known whether this drug may pass into breast milk or not.
Clavulanic Acid: Caution advised during lactation, this drug may excrete into breast milk and make the infant sensitization, so inform your doctor if you are a nursing mother.

Food Interactions:

Delayed absorption of the drug (cefixime) in the presence of food.

Drug Interactions:

Caution always advised when used with other medicines especially cephalosporin antibiotics such as cefaclor, cefadroxil, Cefazolin, Cefdinir, Cefditoren, Cefpodoxime, Cefprozil, Ceftibuten, Cephalexin, Cephradine, Allopurinol, Probencide, and Warfarin etc.

  • Keep Zifi CV tablet 100mg out of sight and reach of children.
  • Store this medicine below 250C, away from heat, moisture, and light.
  • Do not use Zifi CV tablet 100mg beyond its expiry.
  • Use Zifi CV tablet to the full length of the prescribed course.
FDA Pregnancy Category

FDA Pregnancy Category

Category N: No information available.

Drug Composition information
What is Clavulanic acid for:

It is a beta-lactamase inhibitor combined with certain penicillin antibiotics to overcome antibiotic resistance

How does Clavulanic acid work:

Addition of clavulanic acid re-establishes the activity of amoxicillin against bacterias resistant to amoxicillin.

How should Clavulanic acid be used:

Take this drug as directed by the doctor

Common side effects of Clavulanic acid :

GI tolerance is poor specially in children. Other side effects are Candida stomatitisvaginitis and rashes. Some cases of hepatic injury have been reported with the combination.

What do I do if I miss a dose

Take a missed dose as soon as you think about it. - If it is close to the time for your next dose, skip the missed dose and go back to your normal time. - Do not take 2 doses at the same time or extra doses.

What precautions should I take when taking Clavulanic acid :

If you have an allergy to calcium polystyrene sulfonate or any other part of this drug. Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.

When do I need to seek medical help

If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Signs of low potassium. Very bad belly pain. Very hard stools (constipation). Any rash. Side effect or health problem is not better or you are feeling worse.

Can I take Clavulanic acid with other medicines:

Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.

Are there any food restrictions

Avoid Alcohol

How do I store Clavulanic acid :

Store in a cool, dry place away from the reach of children. - Medicines must not be used past the expiry date.

Pregnancy Category

Category B: Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester (and there is no evidence of a risk in later trimesters).

Therapeutic Classification


Seller Information
Manufactured By


at verna ind estate l 56-57,verna goa 403722

Packed By


at verna ind estate l 56-57,verna goa 403722

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